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TERRA R-loops connect and protect sister telomeres in mitosis

Autor: Samantha Sze, Amit Bhardwaj, Priyanka Fnu, Kameron Azarm, Rachel Mund, Katherine Ring, Susan Smith

Publikováno v: Cell Reports, Vol 42, Iss 10, Pp 113235- (2023)

Summary: Resolution of cohesion between sister telomeres in human cells depends on TRF1-mediated recruitment of the polyADP-ribosyltransferase tankyrase to telomeres. In human aged cells, due to insufficient recruitment of TRF1/tankyrase to shortened

Externí odkaz: https://doaj.org/article/5a8b71ed3130479da34414558f5aaff8

FANCM suppresses DNA replication stress at ALT telomeres by disrupting TERRA R-loops.

Autor: Pan, Xiaolei¹, Chen, Yun², Biju, Beena¹, Ahmed, Naveed¹, Kong, Joyce¹, Goldenberg, Marti¹, Huang, Judy¹, Mohan, Nandakumar¹, Klosek, Stephanie¹, Parsa, Kian¹, Guh, Chia-Yu², Lu, Robert³, Pickett, Hilda A.³, Chu, Hsueh-Ping² cchu2017@ntu.edu.tw, Zhang, Dong¹ dzhang12@nyit.edu

Publikováno v: Scientific Reports. 12/13/2019, Vol. 9 Issue 1, p1-14. 14p.

Baryon junction effects on charmonium production in pp and pPb collisions

Autor: Terra, R.

In this work we study the effects of the proton and $Pb$ internal structure on charmonium production at high multiplicities. To do this, we assume that the nucleon has an Y shape, which means that the effective quarks (quarks + antiquarks + gluons) a

Externí odkaz: http://arxiv.org/abs/2404.07743

Detection of TERRA R-Loops at Human Telomeres.

Autor: Glousker G; Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Fernandes RV; Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Feretzaki M; Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Lingner J; Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland. joachim.lingner@epfl.ch.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2022; Vol. 2528, pp. 159-171.