Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Terra Potocky"'
Autor:
Jessica R. Kirshner, Dangshe Ma, Gavin Thurston, William C. Olson, Adam Griesemer, Akiva Mintz, Jon Popke, Lynn E. Macdonald, Andrew Murphy, Hans Gartner, Naxin Tu, Cagan Gurer, Christos A. Kyratsous, Thomas Barry, Mikhail Doubrovin, Nikunj B. Bhatt, Drew Dudgeon, Terra Potocky, Kurt H. Edelmann, Erica Ullman, Aynur Hermann, Karina Bruestle, Fanny Fredriksson, Marcus P. Kelly, Tomas C. Arnold, Carlos Hickey, Sosina Makonnen, Jason T. Giurleo, Makenzie Danton, Richard Tavaré
Assessment of immune-cell subsets within the tumor immune microenvironment is a powerful approach to better understand cancer immunotherapy responses. However, the use of biopsies to assess the tumor immune microenvironment poses challenges, includin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a28c1ce088d993bb73c7f8fe1e2f64
https://doi.org/10.1158/2326-6066.c.6550910.v1
https://doi.org/10.1158/2326-6066.c.6550910.v1
Autor:
Jessica R. Kirshner, Dangshe Ma, Gavin Thurston, William C. Olson, Adam Griesemer, Akiva Mintz, Jon Popke, Lynn E. Macdonald, Andrew Murphy, Hans Gartner, Naxin Tu, Cagan Gurer, Christos A. Kyratsous, Thomas Barry, Mikhail Doubrovin, Nikunj B. Bhatt, Drew Dudgeon, Terra Potocky, Kurt H. Edelmann, Erica Ullman, Aynur Hermann, Karina Bruestle, Fanny Fredriksson, Marcus P. Kelly, Tomas C. Arnold, Carlos Hickey, Sosina Makonnen, Jason T. Giurleo, Makenzie Danton, Richard Tavaré
Supplementary Data from Immuno-PET Monitoring of Lymphocytes Using the CD8-Specific Antibody REGN5054
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc99ef8fb49a9843c409980f336132eb
https://doi.org/10.1158/2326-6066.22545326.v1
https://doi.org/10.1158/2326-6066.22545326.v1
Autor:
Gavin Thurston, Andrew Murphy, Israel Lowy, William Olson, Ella Ioffe, Douglas MacDonald, Markus Mohrs, Jon Popke, Joel Kantrowitz, Dimitris Skokos, Tammy Huang, Joel Martin, William Poueymirou, Ashique Rafique, Elena Garnova, Amanda D’Orvilliers, Qi Wu, Amy Woodruff, Omaira Allbritton, Matt Liu, Seongwon Hong, Venus Lai, Terra Potocky, Janelle Waite, Aynur Hermann, Elena Burova
Measuring binding kinetics of human and mouse PD-1/PD-L1 interactions using surface plasmon resonance.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abdc3e2aa5dabdab092517874e623442
https://doi.org/10.1158/1535-7163.22505004
https://doi.org/10.1158/1535-7163.22505004
Autor:
Gavin Thurston, Andrew Murphy, Israel Lowy, William Olson, Ella Ioffe, Douglas MacDonald, Markus Mohrs, Jon Popke, Joel Kantrowitz, Dimitris Skokos, Tammy Huang, Joel Martin, William Poueymirou, Ashique Rafique, Elena Garnova, Amanda D’Orvilliers, Qi Wu, Amy Woodruff, Omaira Allbritton, Matt Liu, Seongwon Hong, Venus Lai, Terra Potocky, Janelle Waite, Aynur Hermann, Elena Burova
The Programmed Death-1 (PD-1) receptor delivers inhibitory checkpoint signals to activated T cells upon binding to its ligands PD-L1 and PD-L2 expressed on antigen-presenting cells and cancer cells, resulting in suppression of T-cell effector functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17ecc85ae63f9c96791b596fe361f62c
https://doi.org/10.1158/1535-7163.c.6537927.v1
https://doi.org/10.1158/1535-7163.c.6537927.v1
Autor:
Markus Mohrs, Gavin Thurston, Ella Ioffe, Andrew Murphy, William C. Olson, Douglas MacDonald, Joel Martin, William Poueymirou, Ashique Rafique, Jerry Pei, Amy Woodruff, Omaira Allbritton, Matt Liu, Seongwon Hong, Terra Potocky, Gabor Halasz, Erica Ullman, Jie Dai, Aynur Hermann, Elena Burova
Supplementary Figure S2 shows binding of REGN3767 to T cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::118077e089280637142497ec1c10c9a0
https://doi.org/10.1158/1535-7163.22506967
https://doi.org/10.1158/1535-7163.22506967
Autor:
Gavin Thurston, Andrew Murphy, Israel Lowy, William Olson, Ella Ioffe, Douglas MacDonald, Markus Mohrs, Jon Popke, Joel Kantrowitz, Dimitris Skokos, Tammy Huang, Joel Martin, William Poueymirou, Ashique Rafique, Elena Garnova, Amanda D’Orvilliers, Qi Wu, Amy Woodruff, Omaira Allbritton, Matt Liu, Seongwon Hong, Venus Lai, Terra Potocky, Janelle Waite, Aynur Hermann, Elena Burova
SUPPLEMENTARY MATERIALS AND METHODS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30658290e0e4210a655325aea8a9523f
https://doi.org/10.1158/1535-7163.22505010
https://doi.org/10.1158/1535-7163.22505010
Autor:
Gavin Thurston, Andrew Murphy, Israel Lowy, William Olson, Ella Ioffe, Douglas MacDonald, Markus Mohrs, Jon Popke, Joel Kantrowitz, Dimitris Skokos, Tammy Huang, Joel Martin, William Poueymirou, Ashique Rafique, Elena Garnova, Amanda D’Orvilliers, Qi Wu, Amy Woodruff, Omaira Allbritton, Matt Liu, Seongwon Hong, Venus Lai, Terra Potocky, Janelle Waite, Aynur Hermann, Elena Burova
REGN2810 binds to PD-1 on engineered Jurkat cells and on activated human and cynomolgus monkey T cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162c878068951f7d8ad03ab83177d173
https://doi.org/10.1158/1535-7163.22505013
https://doi.org/10.1158/1535-7163.22505013
Autor:
Gavin Thurston, Andrew Murphy, Israel Lowy, William Olson, Ella Ioffe, Douglas MacDonald, Markus Mohrs, Jon Popke, Joel Kantrowitz, Dimitris Skokos, Tammy Huang, Joel Martin, William Poueymirou, Ashique Rafique, Elena Garnova, Amanda D’Orvilliers, Qi Wu, Amy Woodruff, Omaira Allbritton, Matt Liu, Seongwon Hong, Venus Lai, Terra Potocky, Janelle Waite, Aynur Hermann, Elena Burova
Expression of human PD-1 on activated T cells from human PD-1 knock-in mice and expression of PD-L1 on MC38.Ova cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09645018d25dc46a1b76d9d51cf880a2
https://doi.org/10.1158/1535-7163.22505028.v1
https://doi.org/10.1158/1535-7163.22505028.v1
Autor:
Markus Mohrs, Gavin Thurston, Ella Ioffe, Andrew Murphy, William C. Olson, Douglas MacDonald, Joel Martin, William Poueymirou, Ashique Rafique, Jerry Pei, Amy Woodruff, Omaira Allbritton, Matt Liu, Seongwon Hong, Terra Potocky, Gabor Halasz, Erica Ullman, Jie Dai, Aynur Hermann, Elena Burova
In the tumor microenvironment, multiple inhibitory checkpoint receptors can suppress T-cell function, thereby enabling tumor immune evasion. Blockade of one of these checkpoint receptors, PD-1, with therapeutic antibodies has produced positive clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::794b54b1ce635ecec2b0a7d94f0a4214
https://doi.org/10.1158/1535-7163.c.6538528.v1
https://doi.org/10.1158/1535-7163.c.6538528.v1
Autor:
Markus Mohrs, Gavin Thurston, Ella Ioffe, Andrew Murphy, William C. Olson, Douglas MacDonald, Joel Martin, William Poueymirou, Ashique Rafique, Jerry Pei, Amy Woodruff, Omaira Allbritton, Matt Liu, Seongwon Hong, Terra Potocky, Gabor Halasz, Erica Ullman, Jie Dai, Aynur Hermann, Elena Burova
Supplementary Table S2 shows PK data for REGN3767 in monkeys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74d73c9f210d6b41575f2fa53815298a
https://doi.org/10.1158/1535-7163.22506949
https://doi.org/10.1158/1535-7163.22506949