Výsledky vyhledávání - "Tero Wennberg"

Natural Products in the Process of Finding New Drug Candidates

Autor: Tero Wennberg, Maija Leinonen, Pekka Saikku, Jussi-Pekka Rauha, Heikki Vuorela, Päivi Tammela, Pia Vuorela

Publikováno v: University of Helsinki
Scopus-Elsevier

Natural derived or originated compounds still play a major role as drugs, and as lead structures for the development of synthetic molecules. About 50% of the drugs introduced to the market during the last 20 years are derived directly or indirectly f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::442e9294643a7ec42a5ce1b7cf076588
https://doi.org/10.2174/0929867043365116

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Simultaneous Analysis of Alkamides and Caffeic Acid Derivatives for the Identification of Echinacea purpurea, Echinacea angustifolia, Echinacea pallida and Parthenium integrifolium Roots

Autor: Magali Laasonen, Tero Wennberg, Heikki Vuorela, Tuulikki Harmia-Pulkkinen

Publikováno v: Planta Medica. 68:572-574

A reversed-phase HPLC method was developed using a computer simulation program for the identification of dried roots of Echinacea purpurea, E. angustifolia, E. pallida and Parthenium integrifolium. Hydrophilic and lipophilic compounds were analysed s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac7510e9ddcef0c6fe72db000fcaada
https://doi.org/10.1055/s-2002-32561

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Polyketide derivatives active against Botrytis cinerea in Gerbera hybrida

Autor: Jari Yli-Kauhaluoma, Tero Wennberg, Irene Kylänlahti, Kalevi Pihlaja, Pia Vuorela, Teemu H. Teeri, Tiina Auerma, Karel D. Klika, Satu Koskela, P.P. Söderholm, Vladimir V. Ovcharenko, Miia Ainasoja

Publikováno v: Planta. 233(1)

A previously isolated cDNA molecule from Gerbera hybrida (Asteraceae) codes for a new chalcone synthase-like polyketide synthase, 2-pyrone synthase (2PS). 2PS is able to synthesise 4-hydroxy-6-methyl-2-pyrone (triacetolactone), a putative precursor f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::240dac1741d94896a37dd3c94d7809e9
https://pubmed.ncbi.nlm.nih.gov/20878179

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HPLC micro-fractionation coupled to a cell-based assay for automated on-line primary screening of calcium antagonistic components in plant extracts

Autor: Päivi Tammela, Tero Wennberg, Pia Vuorela, Heikki Vuorela

Publikováno v: Analytical and bioanalytical chemistry. 380(4)

High performance liquid chromatography (HPLC) micro-fractionation was successfully coupled to an automated 45Ca2+ uptake assay using GH4C1 cells for the separation of natural product extracts and for the primary detection of their calcium antagonisti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa125bfcbf78d73618aa2f62b0bb59b
https://pubmed.ncbi.nlm.nih.gov/15322796

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