Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Tero Ahola"'
Publikováno v:
Viruses, Vol 16, Iss 10, p 1611 (2024)
The trans-replication system explores the concept of separating the viral RNA involved in the translation of the replicase protein from the replication of the viral genome and has been successfully used to study the replication mechanisms of alphavir
Externí odkaz:
https://doaj.org/article/72395861985746d0bc38bcb08299f844
Autor:
Xiaolei Li, Zhiqiang Wu, Xiaojing An, Qian Mei, Miaomiao Bai, Leena Hanski, Xiang Li, Tero Ahola, Weidong Han
Publikováno v:
eLife, Vol 9 (2020)
Externí odkaz:
https://doaj.org/article/0f779046a0084456b024ffab2bf6bea1
Autor:
Tero Ahola
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
Externí odkaz:
https://doaj.org/article/c9fa065a063e4b0c945a9e70909d403c
Autor:
Benjamin Götte, Marc D Panas, Kirsi Hellström, Lifeng Liu, Baila Samreen, Ola Larsson, Tero Ahola, Gerald M McInerney
Publikováno v:
PLoS Pathogens, Vol 15, Iss 6, p e1007842 (2019)
G3BP-1 and -2 (hereafter referred to as G3BP) are multifunctional RNA-binding proteins involved in stress granule (SG) assembly. Viruses from diverse families target G3BP for recruitment to replication or transcription complexes in order to block SG
Externí odkaz:
https://doaj.org/article/ceeb1136eb2d419ebe38ae687bd9de3e
Publikováno v:
Viruses, Vol 13, Iss 3, p 362 (2021)
Increasing sequence information indicates that RNA viruses constitute a major fraction of marine virus assemblages. However, only 12 RNA virus species have been described, infecting known host species of marine single-celled eukaryotes. Eight of thes
Externí odkaz:
https://doaj.org/article/a7693864a4e343c79cfb611a6db385c9
Autor:
Xiaolei Li, Zhiqiang Wu, Xiaojing An, Qian Mei, Miaomiao Bai, Leena Hanski, Xiang Li, Tero Ahola, Weidong Han
Publikováno v:
eLife, Vol 6 (2017)
Acquired therapeutic resistance by tumors is a substantial impediment to reducing the morbidity and mortality that are attributable to human malignancies. The mechanisms responsible for the dramatic shift between chemosensitivity and chemoresistance
Externí odkaz:
https://doaj.org/article/eefeb770a0e04c03bba5a8e32248396a
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151616 (2016)
Chikungunya virus (CHIKV; genus Alphavirus, family Togaviridae) has recently caused several major outbreaks affecting millions of people. There are no licensed vaccines or antivirals, and the knowledge of the molecular biology of CHIKV, crucial for d
Externí odkaz:
https://doaj.org/article/3148d0e18a55419294b9bc748444dcf0
Publikováno v:
Viruses, Vol 10, Iss 9, p 483 (2018)
The nodavirus flock house virus (FHV) and the alphavirus Semliki Forest virus (SFV) show evolutionarily intriguing similarities in their replication complexes and RNA capping enzymes. In this study, we first established an efficient FHV trans-replica
Externí odkaz:
https://doaj.org/article/3d5f7694d332483faefe0b027704e176
Publikováno v:
Viruses, Vol 9, Iss 10, p 292 (2017)
Semliki Forest virus (SFV) is an arthropod-borne alphavirus that induces membrane invaginations (spherules) in host cells. These harbor the viral replication complexes (RC) that synthesize viral RNA. Alphaviruses have four replicase or nonstructural
Externí odkaz:
https://doaj.org/article/a8011f77729d4f57ab89b2f20ec3bbe9
Autor:
Maarit Neuvonen, Arunas Kazlauskas, Miika Martikainen, Ari Hinkkanen, Tero Ahola, Kalle Saksela
Publikováno v:
PLoS Pathogens, Vol 7, Iss 11, p e1002383 (2011)
Among the four non-structural proteins of alphaviruses the function of nsP3 is the least well understood. NsP3 is a component of the viral replication complex, and composed of a conserved aminoterminal macro domain implicated in viral RNA synthesis,
Externí odkaz:
https://doaj.org/article/468852f140644a40a1029d116a2dba4d