Zobrazeno 1 - 10
of 4 480
pro vyhledávání: '"Terminal Differentiation"'
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-10 (2024)
Abstract Background Epigenetic remodeling at effector gene loci has been reported to be critical in regulating T cell differentiation and function. However, efforts to investigate underlying epigenetic mechanisms that control T cell behaviors have be
Externí odkaz:
https://doaj.org/article/f0ae2805cce347a5a9762ff133689a25
Publikováno v:
Медицинская иммунология, Vol 25, Iss 3, Pp 495-500 (2023)
In recent years, research has revealed a wide variety of erythroid cell functions, including modulation of innate and adaptive immune responses. Anemic or hypoxic stress stimulates a physiological response in the form of stress erythropoiesis, aimed
Externí odkaz:
https://doaj.org/article/b5a783467a624e79a8f177bfe38c3ae6
Autor:
Lehte Türk, Igor Filippov, Christian Arnold, Judith Zaugg, Liina Tserel, Kai Kisand, Pärt Peterson
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
As humans age, their memory T cell compartment expands due to the lifelong exposure to antigens. This expansion is characterized by terminally differentiated CD8+ T cells (Temra), which possess NK cell-like phenotype and are associated with chronic i
Externí odkaz:
https://doaj.org/article/7c983ae33dc644d99c2f03c56307f8ec
Publikováno v:
Patologìâ, Vol 19, Iss 2, Pp 104-109 (2022)
Aim of the study is to determine the peculiarities of epidermal proliferation and terminal differentiation in various histological types of seborrheic keratosis (SK). Materials and methods. Pathomorphological and immunohistochemical analysis was p
Externí odkaz:
https://doaj.org/article/7907ac491dff4924823418b564f70d6a
Autor:
Rebeca Brocal-Ruiz, Ainara Esteve-Serrano, Carlos Mora-Martínez, Maria Luisa Franco-Rivadeneira, Peter Swoboda, Juan J Tena, Marçal Vilar, Nuria Flames
Publikováno v:
eLife, Vol 12 (2023)
Cilia, either motile or non-motile (a.k.a primary or sensory), are complex evolutionarily conserved eukaryotic structures composed of hundreds of proteins required for their assembly, structure and function that are collectively known as the ciliome.
Externí odkaz:
https://doaj.org/article/8039512a71ee4337bbb202560eef249b
Akademický článek
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Autor:
Aidan J. McLaughlin, Anthony I. Kaniski, Darena I. Matti, Nicodemus C. Monear, Jessica L. Tischler, Besa Xhabija
Publikováno v:
Current Research in Toxicology, Vol 5, Iss , Pp 100133- (2023)
Fluorene-9-bisphenol (BHPF) has recently attracted interest as it is increasingly used in industrial settings as a substitute for Bisphenol A (BPA). However, the effects of BHPF exposure on embryonic stem cell (ESC) self-renewal, pluripotency, and di
Externí odkaz:
https://doaj.org/article/4eacd36f3cb64990a11ab863327f1a34
Akademický článek
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Publikováno v:
Journal of Orthopaedic Translation, Vol 30, Iss , Pp 16-30 (2021)
Background: Cyclooxygenase-2 (COX-2) inhibitors are prescribed for the management of osteoarthritis (OA)-associated pain and inflammation. However, the role of COX-2 in normal and osteoarthritic articular chondrocytes has not been well investigated.
Externí odkaz:
https://doaj.org/article/0a314166e05e484580e580c1888654c6
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Corneal blindness is the fourth leading cause of blindness worldwide. The superficial position of cornea on the eye makes this tissue prone to environmental aggressions, which can have a strong impact on sight. While most corneal pathology studies ut
Externí odkaz:
https://doaj.org/article/90528d9a70674e5493ecbac174e4daac