Zobrazeno 1 - 10
of 232
pro vyhledávání: '"Terker A"'
Autor:
Yahua Zhang, Fabian Bock, Mohammed Ferdaus, Juan Pablo Arroyo, Kristie L Rose, Purvi Patel, Jerod S. Denton, Eric Delpire, Alan M. Weinstein, Ming-Zhi Zhang, Raymond C. Harris, Andrew S. Terker
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The renal epithelium is sensitive to changes in blood potassium (K+). We identify the basolateral K+ channel, Kir4.2, as a mediator of the proximal tubule response to K+ deficiency. Mice lacking Kir4.2 have a compensated baseline phenotype w
Externí odkaz:
https://doaj.org/article/466eefddbfcf433986c90e461a6b9ab4
The healthcare domain is one of the most exciting application areas for machine learning, but a lack of model transparency contributes to a lag in adoption within the industry. In this work, we explore the current art of explainability and interpreta
Externí odkaz:
http://arxiv.org/abs/2107.05693
Autor:
Shirong Cao, Yu Pan, Andrew S. Terker, Juan Pablo Arroyo Ornelas, Yinqiu Wang, Jiaqi Tang, Aolei Niu, Sarah Abu Kar, Mengdi Jiang, Wentian Luo, Xinyu Dong, Xiaofeng Fan, Suwan Wang, Matthew H. Wilson, Agnes Fogo, Ming-Zhi Zhang, Raymond C. Harris
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Fibrosis is the progressive accumulation of excess extracellular matrix and can cause organ failure. Fibrosis can affect nearly every organ including kidney and there is no specific treatment currently. Although Epidermal Growth Factor Recep
Externí odkaz:
https://doaj.org/article/843328f669494d6c8eae8c245245903f
Autor:
Wu, Aihua, Wolley, Martin J., Mayr, Hannah L., Cheng, Lei, Cowley, Diane, Li, Bo, Campbell, Katrina L., Terker, Andrew S., Ellison, David H., Welling, Paul A., Fenton, Robert A., Stowasser, Michael
Publikováno v:
In Kidney International Reports June 2023 8(6):1201-1212
Akademický článek
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Autor:
Shirong Cao, Yu Pan, Jiaqi Tang, Andrew S. Terker, Juan Pablo Arroyo Ornelas, Guan-nan Jin, Yinqiu Wang, Aolei Niu, Xiaofeng Fan, Suwan Wang, Raymond C. Harris, Ming-Zhi Zhang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
In obesity, adipose tissue is chronically inflamed, leading to insulin resistance, and adipose tissue macrophages (ATMs) are a major source of cytokines that aggravate adipocyte dysfunction. Here, the authors show that selective deletion of the epide
Externí odkaz:
https://doaj.org/article/ac85aa9123a84c29b4a497e827a2724b
Autor:
Yahua Zhang, Juan Pablo Arroyo, Fabian Bock, Ming‐Zhi Zhang, Raymond C. Harris, Andrew S. Terker
Publikováno v:
Physiological Reports, Vol 11, Iss 8, Pp n/a-n/a (2023)
Abstract High sodium and low potassium intake have both been linked to poor cardiovascular health outcomes and increased mortality rates. A combination of the two is thought to be particularly detrimental. While mechanisms are multiple, the kidney is
Externí odkaz:
https://doaj.org/article/9c5dac886ca04f86a93abb6a93238809
Autor:
Ferdaus, Mohammed Z., Terker, Andrew S., Koumangoye, Rainelli B., Al-Qusairi, Lama, Welling, Paul A., Delpire, Eric
Publikováno v:
American Journal of Physiology: Renal Physiology; Sep2024, Vol. 327 Issue 3, pF373-F385, 13p
Autor:
Pan, Yu, Cao, Shirong, Terker, Andrew S., Tang, Jiaqi, Sasaki, Kensuke, Wang, Yinqiu, Niu, Aolei, Luo, Wentian, Daassi, Dhouha, Fan, Xiaofeng, Wang, Suwan, Wilson, Matthew H., Zhang, Ming-Zhi, Harris, Raymond C.
Publikováno v:
In Kidney International January 2022 101(1):79-91
Autor:
Juan Pablo Arroyo, Andrew S. Terker, Yvonne Zuchowski, Jason A. Watts, Fabian Bock, Cameron Meyer, Wentian Luo, Meghan E. Kapp, Edward R. Gould, Adam X. Miranda, Joshua Carty, Ming Jiang, Roberto M. Vanacore, Elizabeth Hammock, Matthew H. Wilson, Roy Zent, Mingzhi Zhang, Gautam Bhave, Raymond C. Harris
Publikováno v:
JCI Insight, Vol 7, Iss 24 (2022)
Vasopressin has traditionally been thought to be produced by the neurohypophyseal system and then released into the circulation where it regulates water homeostasis. The questions of whether vasopressin could be produced outside of the brain and if t
Externí odkaz:
https://doaj.org/article/f8605fcd021d471dad0702e94a5d9ab1