Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Terina, N."'
Autor:
Sarah Kim, Rebecca J. Willcocks, Michael J. Daniels, Juan Francisco Morales, Deok Yong Yoon, William T. Triplett, Alison M. Barnard, Daniela J. Conrado, Varun Aggarwal, Ramona Belfiore‐Oshan, Terina N. Martinez, Glenn A. Walter, William D. Rooney, Krista Vandenborne
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 10, Pp 1437-1449 (2023)
Abstract Although regulatory agencies encourage inclusion of imaging biomarkers in clinical trials for Duchenne muscular dystrophy (DMD), industry receives minimal guidance on how to use these biomarkers most beneficially in trials. This study aims t
Externí odkaz:
https://doaj.org/article/4d70ad360e114fe3be45ffb256d0e944
Akademický článek
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Autor:
Nicole K. Polinski, Terina N. Martinez, Sylvie Ramboz, Michael Sasner, Mark Herberth, Robert Switzer, Syed O. Ahmad, Lee J. Pelligrino, Sean W. Clark, Jacob N. Marcus, Sean M. Smith, Kuldip D. Dave, Mark A. Frasier
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 6 (2022)
Heterozygous mutations in the GBA1 gene – encoding lysosomal glucocerebrosidase (GCase) – are the most common genetic risk factors for Parkinson's disease (PD). Experimental evidence suggests a correlation between decreased GCase activity and acc
Externí odkaz:
https://doaj.org/article/2ff4a4f7438a460f8a91ec3fc7c58bc4
Autor:
Nicole K Polinski, Terina N Martinez, Alexander Gorodinsky, Ralph Gareus, Michael Sasner, Mark Herberth, Robert Switzer, Syed O Ahmad, Mali Cosden, Monika Kandebo, Robert E Drolet, Peter D Buckett, Weisong Shan, Yi Chen, Lee J Pellegrino, Gregory D Ellsworth, Leo B Dungan, Warren D Hirst, Sean W Clark, Kuldip D Dave
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0252325 (2021)
Multiple mutations have been described in the human GBA1 gene, which encodes the lysosomal enzyme beta-glucocerebrosidase (GCase) that degrades glucosylceramide and is pivotal in glycosphingolipid substrate metabolism. Depletion of GCase, typically b
Externí odkaz:
https://doaj.org/article/294b88f9cc54498d84ccf437a6bd2775
Akademický článek
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Autor:
Polinski, Nicole K.1 (AUTHOR) npolinski@michaeljfox.org, Martinez, Terina N.1 (AUTHOR), Gorodinsky, Alexander2 (AUTHOR), Gareus, Ralph2 (AUTHOR), Sasner, Michael3 (AUTHOR), Herberth, Mark4 (AUTHOR), Switzer, Robert5 (AUTHOR), Ahmad, Syed O.6 (AUTHOR), Cosden, Mali7 (AUTHOR), Kandebo, Monika7 (AUTHOR), Drolet, Robert E.7 (AUTHOR), Buckett, Peter D.8 (AUTHOR), Shan, Weisong8 (AUTHOR), Chen, Yi8 (AUTHOR), Pellegrino, Lee J.9 (AUTHOR), Ellsworth, Gregory D.9 (AUTHOR), Dungan, Leo B.9 (AUTHOR), Hirst, Warren D.8 (AUTHOR), Clark, Sean W.9 (AUTHOR), Dave, Kuldip D.1 (AUTHOR)
Publikováno v:
PLoS ONE. 6/9/2021, Vol. 16 Issue 6, p1-31. 31p.
Autor:
Martin Steger, Federico Diez, Herschel S Dhekne, Pawel Lis, Raja S Nirujogi, Ozge Karayel, Francesca Tonelli, Terina N Martinez, Esben Lorentzen, Suzanne R Pfeffer, Dario R Alessi, Matthias Mann
Publikováno v:
eLife, Vol 6 (2017)
We previously reported that Parkinson’s disease (PD) kinase LRRK2 phosphorylates a subset of Rab GTPases on a conserved residue in their switch-II domains (Steger et al., 2016) (PMID: 26824392). Here, we systematically analyzed the Rab protein fami
Externí odkaz:
https://doaj.org/article/b78ecda69482408fa0764d4064ae35bc
Akademický článek
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Autor:
Lee Pellegrino, Monika Kandebo, Nicole K. Polinski, Mark Herberth, Leo B. Dungan, Robert Switzer, Gregory D. Ellsworth, Sean W. Clark, Alexander Gorodinsky, Robert E. Drolet, Peter D. Buckett, Mali Cosden, Michael Sasner, Ralph Gareus, Syed Omar Ahmad, Weisong Shan, Terina N. Martinez, Kuldip D. Dave, Warren D. Hirst, Yi Chen
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 6, p e0252325 (2021)
PLoS ONE, Vol 16, Iss 6, p e0252325 (2021)
Multiple mutations have been described in the human GBA1 gene, which encodes the lysosomal enzyme beta-glucocerebrosidase (GCase) that degrades glucosylceramide and is pivotal in glycosphingolipid substrate metabolism. Depletion of GCase, typically b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5768efebed44f52b94d2247e7ec2bf9
http://europepmc.org/articles/PMC8189458
http://europepmc.org/articles/PMC8189458
Autor:
McCoy, Melissa K, Ruhn, Kelly A, Martinez, Terina N, McAlpine, Fiona E, Blesch, Armin, Tansey, Malú G
Publikováno v:
In Molecular Therapy September 2008 16(9):1572-1579