Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Teri M. Plona"'
Autor:
Yurong Song, Travis D. Kerr, Chelsea Sanders, Lisheng Dai, Shaneen S. Baxter, Brandon Somerville, Ryan N. Baugher, Stephanie D. Mellott, Todd B. Young, Heidi E. Lawhorn, Teri M. Plona, Bingfang Xu, Lei Wei, Qiang Hu, Song Liu, Alan Hutson, Baktiar Karim, Sandra Burkett, Simone Difilippantonio, Ligia Pinto, Johannes Gebert, Matthias Kloor, Steven M. Lipkin, Shizuko Sei, Robert H. Shoemaker
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundGenome integrity is essential for the survival of an organism. DNA mismatch repair (MMR) genes (e.g., MLH1, MSH2, MSH6, and PMS2) play a critical role in the DNA damage response pathway for genome integrity maintenance. Germline mutations o
Externí odkaz:
https://doaj.org/article/0d2e5d6b71eb4b909e5643961c4ff61e
Autor:
Kajal Biswas, Martin Couillard, Luca Cavallone, Sandra Burkett, Stacey Stauffer, Betty K. Martin, Eileen Southon, Susan Reid, Teri M. Plona, Ryan N. Baugher, Stephanie D. Mellott, Kristen M. Pike, Mary E. Albaugh, Chelsea Maedler-Kron, Nancy Hamel, Lino Tessarollo, Victoria Marcus, William D. Foulkes, Shyam K. Sharan
Publikováno v:
Cell Death and Disease, Vol 12, Iss 9, Pp 1-11 (2021)
Abstract Hereditary non-polyposis colorectal cancer, now known as Lynch syndrome (LS) is one of the most common cancer predisposition syndromes and is caused by germline pathogenic variants (GPVs) in DNA mismatch repair (MMR) genes. A common founder
Externí odkaz:
https://doaj.org/article/60a05c57c3c54a0ab1c477a7c5faeeec
Autor:
Tristan M. Sissung, Roberto H. Barbier, Douglas K. Price, Teri M. Plona, Kristen M. Pike, Stephanie D. Mellott, Ryan N. Baugher, Gordon R. Whiteley, Daniel R. Soppet, David Venzon, Arlene Berman, Arun Rajan, Giuseppe Giaccone, Paul Meltzer, William D. Figg
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 896 (2020)
To ensure accuracy of UGT1A1 (TA)n (rs3064744) genotyping for use in pharmacogenomics-based irinotecan dosing, we tested the concordance of several commonly used genotyping technologies. Heuristic genotype groupings and principal component analysis d
Externí odkaz:
https://doaj.org/article/45f9e85e047e4f279e0370e081533f30
Autor:
Susan W. Reid, William D. Foulkes, Martin Couillard, Kristen M. Pike, Sandra Burkett, Eileen Southon, Nancy Hamel, Mary E. Albaugh, Stacey Stauffer, Chelsea Maedler-Kron, Lino Tessarollo, Kajal Biswas, Luca Cavallone, Victoria Marcus, Shyam K. Sharan, Betty K. Martin, Stephanie D. Mellott, Teri M. Plona, Ryan N. Baugher
Publikováno v:
Cell Death and Disease, Vol 12, Iss 9, Pp 1-11 (2021)
Cell Death & Disease
Cell Death & Disease
Hereditary non-polyposis colorectal cancer, now known as Lynch syndrome (LS) is one of the most common cancer predisposition syndromes and is caused by germline pathogenic variants (GPVs) in DNA mismatch repair (MMR) genes. A common founder GPV in PM
Autor:
Yurong Song, Shaneen Baxter, Lisheng Dai, Chelsea Sanders, Holli Loomans-Kropp, Brandon Somerville, Ryan N. Baugher, Stephanie D. Mellott, Todd B. Young, Heidi E. Lawhorn, Teri M. Plona, Bingfang Xu, Lei Wei, Qiang Hu, Song Liu, Alan Hutson, Baktiar Karim, Simone Difilippantonio, Ligia Pinto, Matthias Kloor, Steven M. Lipkin, Shizuko Sei, Robert H. Shoemaker
Publikováno v:
Cancer Research. 83:6518-6518
DNA mismatch repair (MMR) genes (e.g., MLH1, MSH2, MSH6, PMS2, and EPCAM) play an important role in maintaining genomic stability during DNA replication and recombination. Deficiency in MMR resulting from mutations in these genes leads to mutations i
Autor:
Daniel R. Soppet, Gordon R. Whiteley, Stephanie D. Mellott, Tristan M. Sissung, Paul S. Meltzer, Teri M. Plona, Douglas K. Price, Arlene Berman, William D. Figg, Giuseppe Giaccone, Kristen M. Pike, Arun Rajan, David Venzon, Ryan N. Baugher, Roberto H. Barbier
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 3, p 896 (2020)
Volume 21
Issue 3
International Journal of Molecular Sciences, Vol 21, Iss 3, p 896 (2020)
Volume 21
Issue 3
To ensure accuracy of UGT1A1 (TA)n (rs3064744) genotyping for use in pharmacogenomics-based irinotecan dosing, we tested the concordance of several commonly used genotyping technologies. Heuristic genotype groupings and principal component analysis d
Autor:
Daniel R. Soppet, William D. Figg, Kristen M. Pike, Vivekananda Datta, Mary Barcus, Sharon Adams, Tristan M. Sissung, Jon W. McKeeby, Ellen J. Eckes, Jharana Tina Patel, Gary DiPatrizio, Willy A. Flegel, Frank Mickey, Xiaolin Wu, Barry R. Goldspiel, Stephanie D. Mellott, Parag Kumar, Juan J.L. Lertora, Ryan N. Baugher, Teri M. Plona
Publikováno v:
The Journal of Clinical Pharmacology. 57:S67-S77
The National Institutes of Health Clinical Center (NIH CC) is the largest hospital in the United States devoted entirely to clinical research, with a highly diverse spectrum of patients. Patient safety and clinical quality is a major goal of the hosp
Autor:
Stephan J. Sanders, Edwin C. Oh, Aravinda Chakravarti, Michael E. Talkowski, Michael W. Smith, Vasyl Pihur, Yangfan P. Liu, Edwin H. Cook, Christa Lese Martin, Kristen M. Pike, Maria X. Sosa, Daniel Moreno-De-Luca, Daniel R. Soppet, Sau Wai Cheung, Kamal Sharma, Harrison Brand, Richard L. Huganir, Dallas R. Auer, Ryan L. Collins, Teri M. Plona, Tychele N. Turner, Matthew W. State, Nicholas Katsanis
Publikováno v:
Nature
Autism is a multifactorial neurodevelopmental disorder affecting more males than females; consequently, under a multifactorial genetic hypothesis, females are affected only when they cross a higher biological threshold. We hypothesize that deleteriou