Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Teri L. Aldrich"'
Autor:
Teri L. Aldrich, Frederick W. Jacobsen, Rupa Padaki, Taruna Arora, Martin J. Allen, Jennifer C. Lavallee, Richard J. Armitage, Arvia E. Morris
Publikováno v:
The Journal of Immunology. 186:341-349
Studies for vaccine and human therapeutic Ab development in cynomolgus monkeys (cynos) are influenced by immune responses, with Ab responses playing a significant role in efficacy and immunogenicity. Understanding the nature of cyno humoral immune re
Publikováno v:
Biotechnology Progress. 19:1433-1438
Over the past 10 years, monoclonal antibodies and antibody fragments have become an increasingly important source of therapeutic molecules in the biotechnology industry. Drug development strategies rely on screening large numbers of candidate molecul
Publikováno v:
Cytotechnology. 28:9-17
We have recently reported on the isolation of a 5.7 kb segment of Chinese hamster ovary cell genomic DNA, Expression Augmenting Sequence Element (EASE), which when used in bicistronic expression vectors allows the development of stable Chinese hamste
Publikováno v:
Molecular and Cellular Biology. 13:3424-3433
We developed a genetic selection system based on nonsense suppression in Saccharomyces cerevisiae to identify mutations in proteins involved in transcription initiation by RNA polymerase III. A SUP4 tRNA(Tyr) internal promoter mutation (A53T61) that
Publikováno v:
Molecular and Cellular Biology. 13:3434-3444
Sequence data are presented for the Saccharomyces cerevisiae TAP1 gene and for a mutant allele, tap1-1, that activates transcription of the promoter-defective yeast SUP4 tRNA(Tyr) allele SUP4A53T61. The degree of in vivo activation of this allele by
Publikováno v:
Current Genetics. 23:33-41
A long open reading frame (ORF) closely linked to the Cephalosporium acremonium gene cefEF was identified by DNA sequencing. The cefEF gene encodes the enzyme involved in cephalosporin C (CPC) biosynthesis known as expandase/hydroxylase. Complementat
Publikováno v:
Journal of Bacteriology. 173:4717-4724
CatR, a LysR family protein, positively regulates the Pseudomonas putida catBC operon, which is required for growth on benzoate as a sole carbon source. Transcriptional studies show that the catR and catBC promoters are divergent and overlapping by 2
Autor:
Teri L. Aldrich, R K Rothmel, J. E. Houghton, L. N. Ornston, Wayne Coco, Ananda M. Chakrabarty
Publikováno v:
Journal of Bacteriology. 172:922-931
Pseudomonas putida utilizes the catBC operon for growth on benzoate as a sole carbon source. This operon is positively regulated by the CatR protein, which is encoded from a gene divergently oriented from the catBC operon. The catR gene encodes a 32.
Publikováno v:
Animal Cell Technology: From Target to Market ISBN: 9789401038973
As more genes are being identified through genomic techniques,the need to rapidly express recombinant proteins for functionalstudies has become increasingly acute. Transient expression ofrecombinant protein using COS-1, CV-1 and 293 cells is widelyus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c813144094e51a14a6e1a80b38d1a1f7
https://doi.org/10.1007/978-94-010-0369-8_9
https://doi.org/10.1007/978-94-010-0369-8_9
Autor:
Claudia Roach, Lee E. Hendrickson, C Ray Davis, Phyllis C Mcada, Teri L. Aldrich, Di Kim Nguyen, Christopher D. Reeves
Publikováno v:
Chemistrybiology. 6(7)
Background Lovastatin, an HMG-CoA reductase inhibitor produced by the fungus Aspergillus terreus , is composed of two polyketide chains. One is a nonaketide that undergoes cyclization to a hexahydronaphthalene ring system and the other is a simple di