Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Teri L Moffatt"'
Autor:
Christopher J. Oldfield, Teri L. Moffatt, Kimberley A. O'Hara, Bo Xiang, Vernon W. Dolinsky, Todd A. Duhamel
Publikováno v:
Physiological Reports, Vol 9, Iss 16, Pp n/a-n/a (2021)
Abstract Obesity, type 2 diabetes, and heart disease are linked to an unhealthy diet. Sarco(endo)plasmic reticulum calcium (Ca2+) ATPase 2a (SERCA2a) controls cardiac function by transporting Ca2+ in cardiomyocytes. SERCA2a is altered by diet and ace
Externí odkaz:
https://doaj.org/article/880616f7b546467d8cd271f29449ae6b
Autor:
Sikta Chattopadhyaya, Raghu S. Nagalingam, D. Allison Ledingham, Teri L. Moffatt, Danah S. Al-Hattab, Pavit Narhan, Matthew T. Stecy, Kimberley A. O’Hara, Michael P. Czubryt
Publikováno v:
Cells, Vol 11, Iss 9, p 1471 (2022)
Fibrosis is an energy-intensive process requiring the activation of fibroblasts to myofibroblasts, resulting in the increased synthesis of extracellular matrix proteins. Little is known about the transcriptional control of energy metabolism in cardia
Externí odkaz:
https://doaj.org/article/40bd5647e01a4fed9992742cd6ed6ebf
Autor:
Raghu S Nagalingam, Sikta Chattopadhyaya, Danah S Al-Hattab, David Y C Cheung, Leah Y Schwartz, Sayantan Jana, Nina Aroutiounova, D Allison Ledingham, Teri L Moffatt, Natalie M Landry, Rushita A Bagchi, Ian M C Dixon, Jeffrey T Wigle, Gavin Y Oudit, Zamaneh Kassiri, Davinder S Jassal, Michael P Czubryt
Publikováno v:
European Heart Journal. 43:4739-4750
Aims In response to pro-fibrotic signals, scleraxis regulates cardiac fibroblast activation in vitro via transcriptional control of key fibrosis genes such as collagen and fibronectin; however, its role in vivo is unknown. The present study assessed
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 100:361-370
Sarco(endo)plasmic reticulum calcium (Ca2+) ATPase (SERCA) transports Ca2+ in muscle. Impaired SERCA activity may contribute to diabetic myopathy. Sirtuin (SIRT) 3 regulates muscle metabolism and function; however, it is unknown if SIRT3 regulates mu
Autor:
Devin R. Blizzard LeBlanc, Brittany V. Rioux, Cody Pelech, Teri L. Moffatt, Dustin E. Kimber, Todd A. Duhamel, Vernon W. Dolinsky, Jonathan M. McGavock, Martin Sénéchal
Publikováno v:
Physiological Reports, Vol 5, Iss 23, Pp n/a-n/a (2017)
Abstract The mechanisms underlying the metabolic improvements following aerobic exercise training remain poorly understood. The primary aim of this study was to determine if an adipomyokine, irisin, responded to acute exercise was associated with the
Externí odkaz:
https://doaj.org/article/f1e2f552e1564beb9e5f774f586c1032
Autor:
Sikta Chattopadhyaya, Raghu S. Nagalingam, Pavit Narhan, Dayna A. Ledingham, Teri L. Moffatt, Michael P. Czubryt
Publikováno v:
The FASEB Journal. 36
Autor:
Vernon W. Dolinsky, Bo Xiang, Todd A. Duhamel, Kimberley A. O'Hara, Teri L. Moffatt, Christopher J. Oldfield
Publikováno v:
Physiological Reports
Physiological Reports, Vol 9, Iss 16, Pp n/a-n/a (2021)
Physiological Reports, Vol 9, Iss 16, Pp n/a-n/a (2021)
Obesity, type 2 diabetes, and heart disease are linked to an unhealthy diet. Sarco(endo)plasmic reticulum calcium (Ca2+) ATPase 2a (SERCA2a) controls cardiac function by transporting Ca2+ in cardiomyocytes. SERCA2a is altered by diet and acetylation,
Autor:
Theodore J. Wigle, Todd A. Duhamel, Kimberley A. O'Hara, Marc Morissette, Thomas Netticadan, Jeffrey T. Wigle, Andrew N. Stammers, Teri L. Moffatt, Shanel E. Susser, Sheena Premecz, Davinder S. Jassal
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 97:786-795
Exercise enhances cardiac sarcoplasmic reticulum Ca2+-ATPase 2a (SERCA2a) function through unknown mechanisms. The present study tested the hypothesis that the positive effects of exercise on SERCA2a expression and function in the left ventricle is d
Autor:
Teri L. Moffatt, Brett Hiebert, Dustin E. Kimber, D. Scott Kehler, Brittany N. Semenchuk, Shaelyn M. Strachan, Rakesh C. Arora, Denise E. Cornish, Todd A. Duhamel, Jacqueline L. Hay, Andrew N. Stammers, Eduardo Caldas Costa, David E. Kent, Naomi C. Hamm, Kevin F. Boreskie
Publikováno v:
Experimental Gerontology. 119:40-44
Standardizing the Fried criteria (S-FC) using cutoffs specific to the patient population improves adverse outcome prediction. However, there is limited evidence to determine if a S-FC assessment can improve discrimination of cardiovascular disease (C
Autor:
Liam A.Thompson, Todd A. Duhamel, Brett Hiebert, Kevin F. Boreskie, Christopher J. Oldfield, Teri L. Moffatt, Rakesh C. Arora
Publikováno v:
Advances in Geriatric Medicine and Research.
Background: Frailty and cardiovascular disease (CVD) share common pathophysiology in their progression. Declines in bone health often occur concomitantly with frailty and CVD. Therefore, analytes of bone metabolism may be useful biomarkers of pre-fra