Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tereza Ventura-Holman"'
Publikováno v:
Gene. 408:95-103
Retinoic acid (RA) exerts profound effects on multiple aspects of vertebrate development, homeostasis and cellular differentiation. Although the liver is a major target organ for RA, no data exist on global expression of RA-responsive genes in hepato
Publikováno v:
Gene. 396:332-337
Thyroid hormone (T3) plays an important role in gene regulation in the liver. Previous studies have been done in complex systems such as animal models, or in transformed malignant hepatic cell lines in which thyroid hormone receptor (TR) was over-exp
Autor:
Tereza Ventura-Holman, Deyin Lu, Jing Li, Joseph F. Maher, Jose S. Subauste, Robert W. McMurray
Publikováno v:
Molecular and Cellular Biology. 25:6570-6577
Type 2 diabetes mellitus is a disorder of glucose homeostasis involving complex gene and environmental interactions that are incompletely understood. Mammalian homologs of nematode sex determination genes have recently been implicated in glucose home
Publikováno v:
Tumor Biology. 26:294-299
Rhabdomyosarcoma (RMS) is the most common soft tissue neoplasm of children, and those metastatic at presentation have a poor prognosis. RMS development is related to defective skeletal muscle differentiation, involving a variety of cell signaling and
Publikováno v:
Gene. 314:133-139
The fem-1 gene of Caenorhabditis elegans functions in a signaling pathway that controls sex determination. Homologs of fem-1 in mammals have been characterized, consisting of two family members, Fem1a and Fem1b. We report here on Fem1c, a third membe
Autor:
Joseph F. Maher, Tereza Ventura-Holman
Publikováno v:
Biochemical and Biophysical Research Communications. 267:317-320
The FEM-1 protein of Caenorhabditis elegans functions within the nematode sex-determination pathway. Two mouse homologs, encoded by the Fem1a and Fem1b genes, have been reported. We report here the characterization of a novel human gene, designated F
Autor:
Owen J. Sansom, Deyin Lu, M. Cecilia Subauste, Liqin Du, Tereza Ventura-Holman, Joseph F. Maher
Publikováno v:
Cancer epidemiology. 35(1)
Background : Colorectal cancer is preventable by early detection and removal of precursor lesions. Central to early stages of colorectal neoplasia is activation of Wnt signaling, usually due to inactivation of the Apc tumor suppressor gene for which
Publikováno v:
Molecular biology reports. 38(2)
Mutant forms of thyroid hormone receptor (TR) with dominant negative activity are frequently found in human hepatocellular carcinoma (HCC). Interestingly, the v-erbA oncogene, known to exert a dominant-negative effect on the expression of thyroid hor
Publikováno v:
The American Journal of the Medical Sciences. 319:268-270
We have identified a novel human gene, FEM1B, that encodes a protein virtually identical to that encoded by the mouse gene Fem1b. These mammalian proteins are homologs of the FEM-1 protein of Caenorhabditis elegans, which acts as a signal-transductio