Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Tereza Nehybová"'
Autor:
Tereza Nehybová, Jan Šmarda, Lukáš Daniel, Marek Stiborek, Viktor Kanický, Ivan Spasojevič, Jan Preisler, Jiří Damborský, Petr Beneš
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 4, p 729 (2017)
Wedelolactone is a multi-target natural plant coumestan exhibiting cytotoxicity towards cancer cells. Although several molecular targets of wedelolactone have been recognized, the molecular mechanism of its cytotoxicity has not yet been elucidated. I
Externí odkaz:
https://doaj.org/article/fe7e603d4fa344d782c17c37ea952700
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 152:76-83
Wedelolactone, a plant coumestan, was shown to act as anti-cancer agent for breast and prostate carcinomas in vitro and in vivo targeting multiple cellular proteins including androgen receptors, 5-lipoxygenase and topoisomerase IIα. It is cytotoxic
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 14:1351-1362
Natural products are often used in drug development due to their ability to form unique and diverse chemical structures. Coumestans are polycyclic aromatic plant secondary metabolites containing a coumestan moiety, which consists of a benzoxole fused
Autor:
Jan Preisler, Petr Beneš, Tereza Nehybová, Lukas Daniel, Jan Šmarda, Jiří Damborský, Ivan Spasojevic, Viktor Kanický, Marek Stiborek
Publikováno v:
International Journal of Molecular Sciences; Volume 18; Issue 4; Pages: 729
International Journal of Molecular Sciences, Vol 18, Iss 4, p 729 (2017)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 18, Iss 4, p 729 (2017)
International Journal of Molecular Sciences
Wedelolactone is a multi-target natural plant coumestan exhibiting cytotoxicity towards cancer cells. Although several molecular targets of wedelolactone have been recognized, the molecular mechanism of its cytotoxicity has not yet been elucidated. I
Autor:
Lucia Knopfová, Eva Slabáková, Jan Bouchal, Ján Remšík, Gvantsa Kharaishvili, Petr Beneš, Lucia Binó, Tereza Nehybová, Radek Fedr, Šárka Šimečková, Karel Souček, Milan Král, Zuzana Kahounová
Publikováno v:
Cancer Research. 78:B084-B084
Dissemination of cancer cells to distant organs has fatal consequences to most of the patients with malignant tumors. Patients with prostate and breast cancer show apparent overlap of the most common sites of cancer metastasis, suggesting that breast
Autor:
Nehybová, Tereza1,2 322903@mail.muni.cz, Šmarda, Jan1 smarda@sci.muni.cz, Daniel, Lukáš2,3 211165@mail.muni.cz, Stiborek, Marek4 408516@mail.muni.cz, Kanický, Viktor4,5 viktor.kanicky@ceitec.muni.cz, Spasojevič, Ivan6 redoxsci@gmail.com, Preisler, Jan4,5 preisler@chemi.muni.cz, Damborský, Jiří2,3 jiridamborsky0@gmail.com, Beneš, Petr1,2 pbenes@sci.muni.cz
Publikováno v:
International Journal of Molecular Sciences. Apr2017, Vol. 18 Issue 4, p729. 18p. 1 Diagram, 1 Chart, 10 Graphs.