Zobrazeno 1 - 10
of 192
pro vyhledávání: '"Tereza, Martinu"'
Autor:
Mitsuaki Kawashima, Jillian D. Oliver, Tatsuaki Watanabe, Hisashi Oishi, Ning Huang, Chihiro Konoeda, Shin Hirayama, David M. Hwang, Qixuan Li, Ella Huszti, Mingyao Liu, Shaf Keshavjee, Stephen Juvet, Tereza Martinu
Publikováno v:
JHLT Open, Vol 4, Iss , Pp 100050- (2024)
Background: The mouse orthotopic single lung transplant (LTx) model is an important scientific tool to explore LTx immunology. C57BL/10J (B10, H-2b) to C57BL/6J (B6, H-2b) minor alloantigen-mismatched LTx exhibits mild acute rejection and chronic fib
Externí odkaz:
https://doaj.org/article/b52e6c937e4f4294a06ab4161bffb28a
Autor:
Natalia Belousova, Albert Cheng, John Matelski, Anastasiia Vasileva, Joyce K. Y. Wu, Rasheed Ghany, Tereza Martinu, Clodagh M. Ryan, Chung-Wai Chow
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
IntroductionPrior studies assessing outcomes of lung transplants from cigarette-smoking donors found mixed results. Oscillometry, a non-invasive test of respiratory impedance, detects changes in lung function of smokers prior to diagnosis of COPD, an
Externí odkaz:
https://doaj.org/article/aade92dba3d9403b90c8c93b88110b1c
Autor:
Andrew T. Sage, Laura L. Donahoe, Alaa A. Shamandy, S. Hossein Mousavi, Bonnie T. Chao, Xuanzi Zhou, Jerome Valero, Sharaniyaa Balachandran, Aadil Ali, Tereza Martinu, George Tomlinson, Lorenzo Del Sorbo, Jonathan C. Yeung, Mingyao Liu, Marcelo Cypel, Bo Wang, Shaf Keshavjee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)
Abstract Ex vivo lung perfusion (EVLP) is a data-intensive platform used for the assessment of isolated lungs outside the body for transplantation; however, the integration of artificial intelligence to rapidly interpret the large constellation of cl
Externí odkaz:
https://doaj.org/article/af760de30b88434f8af5439b2c782944
Autor:
Rafaela V.P. Ribeiro, MD, PhD, Anas Samman, BSc, Aizhou Wang, PhD, Stella Wang, BSc, MSc, Tereza Martinu, MD, MHS, Shaf Keshavjee, MSc, MD, Lianne G. Singer, MD, Deepali Kumar, MSc, MD, Atul Humar, MSc, MD, Marcelo Cypel, MSc, MD
Publikováno v:
JTCVS Open, Vol 14, Iss , Pp 590-601 (2023)
Objectives: Cytomegalovirus infection after lung transplant is associated with increased morbidity and mortality. Inflammation, infection, and longer ischemic times are important risk factors for cytomegalovirus infection. Ex vivo lung perfusion has
Externí odkaz:
https://doaj.org/article/4940f9312e764aaf86890a469fd91be2
Autor:
Antti I. Nykänen, Andrea Mariscal, Allen Duong, Aadil Ali, Akihiro Takahagi, Xiaohui Bai, Guan Zehong, Betty Joe, Mamoru Takahashi, Manyin Chen, Hemant Gokhale, Hongchao Shan, David M. Hwang, Catalina Estrada, Jonathan Yeung, Tom Waddell, Tereza Martinu, Stephen Juvet, Marcelo Cypel, Mingyao Liu, John E. Davies, Shaf Keshavjee
Publikováno v:
Cells, Vol 13, Iss 10, p 859 (2024)
Lung transplantation results are compromised by ischemia–reperfusion injury and alloimmune responses. Ex vivo lung perfusion (EVLP) is used to assess marginal donor lungs before transplantation but is also an excellent platform to apply novel thera
Externí odkaz:
https://doaj.org/article/d7513c66d54a448fb8dd71f93efea334
Autor:
Tatsuaki Watanabe, Stephen C. Juvet, Gregory Berra, Jan Havlin, Wenshan Zhong, Kristen Boonstra, Tina Daigneault, Miho Horie, Chihiro Konoeda, Grace Teskey, Zehong Guan, David M. Hwang, Mingyao Liu, Shaf Keshavjee, Tereza Martinu
Publikováno v:
JCI Insight, Vol 8, Iss 21 (2023)
Chronic lung allograft dysfunction (CLAD) is a major complication after lung transplantation that results from a complex interplay of innate inflammatory and alloimmune factors, culminating in parenchymal and/or obliterative airway fibrosis. Excessiv
Externí odkaz:
https://doaj.org/article/828d5f42c5fc450bafa748ee71199fb8
Autor:
Rayoun Ramendra, Juan C. Fernández-Castillo, Ella Huszti, Rasheed Ghany, Meghan Aversa, Jan Havlin, Peter Riddell, Cecilia M. Chaparro, Lianne G. Singer, Louis Liu, Shaf Keshavjee, Jonathan C. Yeung, Tereza Martinu
Publikováno v:
ERJ Open Research, Vol 9, Iss 5 (2023)
Background Morbidity and mortality in lung transplant recipients are often triggered by recurrent aspiration events, potentiated by oesophageal and gastric disorders. Previous small studies have shown conflicting associations between oesophageal func
Externí odkaz:
https://doaj.org/article/4bcc86e5fb554d09aaf500856ddf59c8
Autor:
Gavin W. Wilson, Allen Duong, Sajad Moshkelgosha, Gary Bader, Shaf Keshavjee, Tereza Martinu, Stephen C. Juvet, Jonathan C. Yeung
Publikováno v:
Frontiers in Transplantation, Vol 2 (2023)
BackgroundSingle-cell RNA-sequencing (scRNA-seq) technology has revealed novel cell populations in organs, uncovered regulatory relationships between genes, and allowed for tracking of cell lineage trajectory during development. It demonstrates promi
Externí odkaz:
https://doaj.org/article/6fbb4fba39644a7597b3210636605cb1
Autor:
Chen Yang Kevin Zhang, Musawir Ahmed, Ella Huszti, Liran Levy, Sarah E. Hunter, Kristen M. Boonstra, Sajad Moshkelgosha, Andrew T. Sage, Sassan Azad, Rasheed Ghany, Jonathan C. Yeung, Oscar M. Crespin, Lianne G. Singer, Shaf Keshavjee, Tereza Martinu
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-12 (2022)
Abstract Background Bronchoalveolar lavage (BAL) is a key tool in respiratory medicine for sampling the distal airways. BAL bile acids are putative biomarkers of pulmonary microaspiration, which is associated with poor outcomes after lung transplanta
Externí odkaz:
https://doaj.org/article/3805e876b2e04c56bd17d1a606b8aa57
Autor:
Anastasiia Vasileva, Nour Hanafi, Ella Huszti, John Matelski, Natalia Belousova, Joyce K. Y. Wu, Tereza Martinu, Rasheed Ghany, Shaf Keshavjee, Jussi Tikkanen, Marcelo Cypel, Jonathan C. Yeung, Clodagh M. Ryan, Chung-Wai Chow
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundChronic lung allograft dysfunction (CLAD) is the major cause of death post-lung transplantation, with acute cellular rejection (ACR) being the biggest contributing risk factor. Although patients are routinely monitored with spirometry, FEV1
Externí odkaz:
https://doaj.org/article/2defbe50f0bb477fa163a2215297232e