Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Teresa Zulueta-Coarasa"'
Autor:
John Fadul, Teresa Zulueta-Coarasa, Gloria M. Slattum, Nadja M. Redd, Mauricio Franco Jin, Michael J. Redd, Stephan Daetwyler, Danielle Hedeen, Jan Huisken, Jody Rosenblatt
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
The ability to visualise stochastic invasion events is limited in murine models of metastatic cancers. Here the authors use a transparent zebrafish epidermis model to follow the invasion events of K-Ras transformed epithelial cells and show that thes
Externí odkaz:
https://doaj.org/article/61d4a58f438f4d42b3f1128793ae1242
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105330- (2022)
Summary: Metastasis is tightly linked with poor cancer prognosis, yet it is not clear how transformed cells become invasive carcinomas. We previously discovered that single KRasV12-transformed cells can invade directly from the epithelium by basal ce
Externí odkaz:
https://doaj.org/article/f7547226e5044eef84e5060ef88bcd7d
Autor:
Oindrila De, Clinton Rice, Teresa Zulueta-Coarasa, Rodrigo Fernandez-Gonzalez, Robert E. Ward
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Septate junctions (SJs) serve as occluding barriers in invertebrate epithelia. In Drosophila, at least 30 genes are required for the formation or maintenance of SJs. Interestingly, loss-of-function mutations in core SJ components are embryonic lethal
Externí odkaz:
https://doaj.org/article/ac26bb3059a149a3b13d483bd05a0eb8
Publikováno v:
Nature Physics. 14:750-758
Embryonic wounds heal rapidly, in a process driven by coordinated cell movements. Polarization of actin and the molecular motor non-muscle myosin II in the cells adjacent to the wound results in the formation of a supracellular cable around the wound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71efb3176b7a53fbb2ddeb3d53fca980
https://doi.org/10.1038/s41567-018-0111-2
https://doi.org/10.1038/s41567-018-0111-2
Autor:
Teresa Zulueta-Coarasa, Guy Tanentzapf, Emily Lostchuck, Kaitlyn M. L. Cramb, Katharine Goodwin, Rodrigo Fernandez-Gonzalez
Publikováno v:
Molecular Biology of the Cell
Cell–extracellular matrix (ECM) and cell–cell adhesion are interdependent during dorsal closure in the fly. Cell–ECM adhesion is required for normal myosin dynamics and organization of both cell–cell adhesions and actin networks during dorsal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fee806b793cc43d684831dca7a041242
https://doi.org/10.1091/mbc.e17-01-0033
https://doi.org/10.1091/mbc.e17-01-0033
Autor:
Laura Prochazka, Nika Shakiba, Teresa Zulueta-Coarasa, Rodrigo Fernandez-Gonzalez, Joel Ostblom, Mukul Tewary, Peter W. Zandstra
Publikováno v:
Development (Cambridge, England)
How position-dependent cell fate acquisition occurs during embryogenesis is a central question in developmental biology. To study this process, we developed a defined, high-throughput assay to induce peri-gastrulation-associated patterning in geometr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74a81225ee82e0880a9423c8c7f87c30
http://europepmc.org/articles/PMC5769627
http://europepmc.org/articles/PMC5769627
Autor:
Katharine Goodwin, Teresa Zulueta-Coarasa, Guy Tanentzapf, Rodrigo Fernandez-Gonzalez, Emily Lostchuck, Stephanie J. Ellis
Publikováno v:
Developmental Cell. 39:611-625
Tissue morphogenesis requires force-generating mechanisms to organize cells into complex structures. Although many such mechanisms have been characterized, we know little about how forces are integrated across developing tissues. We provide evidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc7b5ff9c2babd4745e2e70341982754
https://doi.org/10.1016/j.devcel.2016.11.003
https://doi.org/10.1016/j.devcel.2016.11.003
Autor:
Teresa Zulueta-Coarasa, Danielle Hedeen, Jan Huisken, Stephan Daetwyler, Jody Rosenblatt, John Fadul, Michael J. Redd, Nadja M Redd, Gloria Slattum
Metastasis is the predominant reason that patients succumb to cancer, yet the mechanisms that drive initial tumor cell invasion are poorly understood. We previously discovered that crowding-induced apical extrusion drives most epithelial cell death,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d38753ef6862012785229ff9623d3f
Autor:
Sahar Javaherian, Benjamin Slater, Teresa Zulueta-Coarasa, Rodrigo Fernandez-Gonzalez, Alison P. McGuigan, Elisa D'Arcangelo
Publikováno v:
Integrative Biology. 7:298-312
During development and in adult tissues separation of phenotypically distinct cell populations is necessary to ensure proper organization and function of tissues and organs. Various phenomena, such as differential adhesion, differential mechanical te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::290168dbc725f8bf244e426f466f2b54
https://doi.org/10.1039/c4ib00272e
https://doi.org/10.1039/c4ib00272e
Publikováno v:
Development. 141:2901-2911
The embryonic epidermis displays a remarkable ability to repair wounds rapidly. Embryonic wound repair is driven by the evolutionary conserved redistribution of cytoskeletal and junctional proteins around the wound. Drosophila has emerged as a model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a029cd7e46924fb610968757c10774f5
https://doi.org/10.1242/dev.106898
https://doi.org/10.1242/dev.106898