Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Teresa Zieniawa"'
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry. 20:115-121
A series of N-acyl peptides 1-9, containing an inhibitor of glucosamine-6-phosphate synthase have been synthesised and tested against Candida strains. N-Acylated peptides inhibit glucosamine-6-phosphate synthase in cell free extracts from Candida alb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff9ef627d2491df5dd4d9313e1856401
https://doi.org/10.1080/14756360400009317
https://doi.org/10.1080/14756360400009317
Publikováno v:
European Journal of Medicinal Chemistry. 29:61-67
A series of peptides with N 3 -( S )-bromosuccinamoyl-( S )-2,3-diaminopropanoic acid, a novel selective inhibitor of glucosamine-6-phosphate synthase were synthesized and evaluated in vitro for antimicrobial activity against selected bacterial and f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fc419aea19a8f7551b19a25b70af5d9
https://doi.org/10.1016/0223-5234(94)90127-9
https://doi.org/10.1016/0223-5234(94)90127-9
Publikováno v:
The Journal of Antibiotics. 47:715-723
Peptide analogues of Sch 37137 the antifungal antibiotic have been synthesized and evaluated in vitro against Candida sp. Di- and tripeptides containing methionine, leucine, norvaline, lysine, glutamic acid and N3-(trans-epoxysuccinamoyl)-L-2,3-diami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1333f9bbdf5f9c47f6d8735522a4a66a
https://doi.org/10.7164/antibiotics.47.715
https://doi.org/10.7164/antibiotics.47.715
Autor:
Sławomir Milewski, Teresa Zieniawa, Pawel Sowinski, Edward Borowski, Wilfried A. König, Andrzej Czerwinski, Volker Sinnwell
Publikováno v:
The Journal of Antibiotics. 44:979-984
The synthesis of new N-alkyl amphotericin B derivatives obtained in the Michael addition reaction of the antibiotic with N-substituted maleimides is described and in vitro biological data are presented.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da5e20dff0432f7a98bf20b4ddd1c9c0
https://doi.org/10.7164/antibiotics.44.979
https://doi.org/10.7164/antibiotics.44.979
Publikováno v:
Journal of Medicinal Chemistry. 33:132-135
Tri-, tetra-, and pentapeptides containing N3-(4-methoxyfumaroyl)-L-2,3-diaminopropanoic acid (FMDP), an inactivator of glucosamine 6-phosphate synthase of fungal origin (a key enzyme in the biosynthesis of macromolecular components of the fungal cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9408ef019015cad068bb7771aa17f5e
https://doi.org/10.1021/jm00163a022
https://doi.org/10.1021/jm00163a022
Publikováno v:
The Journal of Antibiotics. 50:709-711
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a70db84dbc1347e4f749ad93a41ed327
https://doi.org/10.7164/antibiotics.50.709
https://doi.org/10.7164/antibiotics.50.709
Autor:
Robert Jedrzejczak, Marek Wojciechowski, Teresa Zieniawa, Ryszard Andruszkiewicz, Edward Borowski
Publikováno v:
Journal of enzyme inhibition. 15(5)
Novel inhibitors 1–4 of glucosamine-6-phosphate synthase from Candida albicans have been designed based on acylation of the N3 amino group of L-2,3-diaminopropanoic acid with the corresponding ketoacids. These inhibitors have been shown to alkylate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12683c2dfa0fb8ea553a0d66b1ae7550
https://pubmed.ncbi.nlm.nih.gov/11030083
https://pubmed.ncbi.nlm.nih.gov/11030083
Publikováno v:
Journal of medicinal chemistry. 33(10)
Six peptide conjugates consisting of either norvaline, methionine, or lysine and N3-(iodoacetyl)-L-2,3-diaminopropanoic acid--a strong, irreversible inactivator of bacterial and fungal glucosamine-6-phosphate synthase--were synthesized and their anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7739bf559cd062b2381ebafc9dc66a48
https://pubmed.ncbi.nlm.nih.gov/2120441
https://pubmed.ncbi.nlm.nih.gov/2120441
Publikováno v:
The Journal of antibiotics. 43(6)
The synthesis of amphotericin B 2-morpholinoethylamide diaspartate, a new water soluble antibiotic derivative with improved selective toxicity is described and in vitro biological data are presented.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::106932c9b4044eb43fdd7def7f7c6608
https://pubmed.ncbi.nlm.nih.gov/2380114
https://pubmed.ncbi.nlm.nih.gov/2380114