Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Teresa Ward"'
Publikováno v:
Digital Health, Vol 9 (2023)
Objective Chronic diseases are the leading causes of death and disability in the U.S., and disease management largely falls onto patients’ family caregivers. The long-term burden and stress of caregiving negatively impact caregivers’ well-being a
Externí odkaz:
https://doaj.org/article/23bdf464093d48e5916a478923e0f30d
Autor:
Lorey K. Smith, Tiffany Parmenter, Margarete Kleinschmidt, Eric P. Kusnadi, Jian Kang, Claire A. Martin, Peter Lau, Riyaben Patel, Julie Lorent, David Papadopoli, Anna Trigos, Teresa Ward, Aparna D. Rao, Emily J. Lelliott, Karen E. Sheppard, David Goode, Rodney J. Hicks, Tony Tiganis, Kaylene J. Simpson, Ola Larsson, Benjamin Blythe, Carleen Cullinane, Vihandha O. Wickramasinghe, Richard B. Pearson, Grant A. McArthur
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Different adaptive mechanisms have been reported to reduce the efficacy of mutant BRAF inhibition in melanoma. Here, the authors show BRAF inhibition induces the translational regulation of metabolic genes leading to acquired therapy resistance.
Externí odkaz:
https://doaj.org/article/059612c027f74f17b5f4fdc038786683
Publikováno v:
BMJ Open, Vol 12, Iss 2 (2022)
Externí odkaz:
https://doaj.org/article/21f03f35e4de4230b51189ea5ac5132e
Autor:
Peter S. Linsley, Steven R. Bartz, Hongyue Dai, Matthew Biery, Teresa Ward, Sumire Kobayashi, Mao Mao, Aimee L. Jackson
Publikováno v:
Cancer Informatics, Vol 6, Pp 147-164 (2008)
We identified gene expression signatures predicting responsiveness to a Kinesin-5 (KIF11) inhibitor (Kinesin-5i) in cultured colon tumor cell lines. Genes predicting resistance to Kinesin-5i were enriched for those from chromosome 20q, a region of fr
Externí odkaz:
https://doaj.org/article/c4dbdba1f5c54bd0b005e9aefff4a564
Autor:
Aimee L. Jackson, Mao Mao, Sumire Kobayashi, Teresa Ward, Matthew Biery, Hongyue Dai, Steven R. Bartz, Peter S. Linsley
Publikováno v:
Cancer Informatics, Vol 6 (2008)
We identified gene expression signatures predicting responsiveness to a Kinesin-5 (KIF11) inhibitor (Kinesin-5i) in cultured colon tumor cell lines. Genes predicting resistance to Kinesin-5i were enriched for those from chromosome 20q, a region of fr
Externí odkaz:
https://doaj.org/article/db372962b62145a69b95174054182e34
Autor:
Shameka Phillips, Peng Li, Teresa Ward, Paula Chandler-Laney, Pamela Bowen, Olivia Affuso, Marti Rice
Publikováno v:
SLEEP. 46:A333-A333
Introduction Elevated blood pressure (BP) is an important modifiable risk factor for cardiovascular disease (CVD), the leading cause of death in the world. Elevated BP in adolescence increases the risk for CVD in adulthood. Unfortunately, 1.3 million
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbb1891e535a79d0f8e9dcea8edb7891
https://doi.org/10.1093/sleep/zsad077.0755
https://doi.org/10.1093/sleep/zsad077.0755
Autor:
Ygal Haupt, Prerana Ghosh, Carleen Cullinane, Natalie Brajanovski, Gretchen Poortinga, Ian P. Street, Emily J. Lelliott, Laura Kirby, Keefe T. Chan, Mark G. Devlin, Richard B. Pearson, Elaine Sanij, Shatha AbuHammad, Lorey K. Smith, Michael A. Davies, Anthony T. Papenfuss, Alison Slater, Kerry Ardley, Sue Haupt, Karen E. Sheppard, Peter Lau, David J. Curtis, Hendrik Falk, Stupple Paul Anthony, Huiqin Chen, Grant A. McArthur, Margarete Kleinschmidt, Zoe Bacolas, Teresa Ward, Claire Martin, Aparna D. Rao, Ismael A. Vergara
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Targeting CDK4/6 shows great promise in the treatment of many solid cancers, including melanoma. This study has uncovered a mechanism of action of CDK4/6 inhibitors in regulating the MDM4 oncogene and the tumor suppressor, p53. In melano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3c463a6eb580dc81263393215e3d7a1
https://doi.org/10.1073/pnas.1901323116
https://doi.org/10.1073/pnas.1901323116
Publikováno v:
Gastroenterology. 162:S-948
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4615fe2d02046731201f7d1a21875570
https://doi.org/10.1016/s0016-5085(22)62245-5
https://doi.org/10.1016/s0016-5085(22)62245-5
Publikováno v:
BMJ Open, Vol 12, Iss 2 (2022)
IntroductionAsthma is an incurable, lifelong condition that places children at increased risk for exacerbation, hospitalisation and school absences. Most paediatric asthma interventions target parents alone and are overly prescriptive. Improving Asth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::349d20897a28a2f324fe0b37df8a7c67
https://doi.org/10.1136/bmjopen-2021-059791
https://doi.org/10.1136/bmjopen-2021-059791
Autor:
Lorey K, Smith, Tiffany, Parmenter, Margarete, Kleinschmidt, Eric P, Kusnadi, Jian, Kang, Claire A, Martin, Peter, Lau, Riyaben, Patel, Julie, Lorent, David, Papadopoli, Anna, Trigos, Teresa, Ward, Aparna D, Rao, Emily J, Lelliott, Karen E, Sheppard, David, Goode, Rodney J, Hicks, Tony, Tiganis, Kaylene J, Simpson, Ola, Larsson, Benjamin, Blythe, Carleen, Cullinane, Vihandha O, Wickramasinghe, Richard B, Pearson, Grant A, McArthur
Publikováno v:
Nature communications. 13(1)
Despite the success of therapies targeting oncogenes in cancer, clinical outcomes are limited by residual disease that ultimately results in relapse. This residual disease is often characterized by non-genetic adaptive resistance, that in melanoma is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d52ce46f7023ed498ed0ad7d09b863db
https://pubmed.ncbi.nlm.nih.gov/35232962
https://pubmed.ncbi.nlm.nih.gov/35232962