Acid stress signals are integrated into the σB-dependent general stress response pathway via the stressosome in the food-borne pathogen Listeria monocytogenes.

Autor: Duarte N Guerreiro, M Graciela Pucciarelli, Teresa Tiensuu, Diana Gudynaite, Aoife Boyd, Jörgen Johansson, Francisco García-Del Portillo, Conor P O'Byrne

Publikováno v: PLoS Pathogens, Vol 18, Iss 3, p e1010213 (2022)

The general stress response (GSR) in Listeria monocytogenes plays a critical role in the survival of this pathogen in the host gastrointestinal tract. The GSR is regulated by the alternative sigma factor B (σB), whose role in protection against acid

Externí odkaz: https://doaj.org/article/607ee03bb1d343feacf787f0e3836aad

Listeria monocytogenes requires the RsbX protein to prevent SigB-activation under non-stressed conditions

Autor: Hasan Tükenmez, Ana H. Oliveira, Duarte N. Guerreiro, Francisco García-del Portillo, Jörgen Johansson, Charlotte Dessaux, Teresa Tiensuu, Conor P. O'Byrne

Publikováno v: Journal of Bacteriology

The survival of microbial cells under changing environmental conditions requires an efficient reprogramming of transcription, often mediated by alternative sigma factors. The Gram-positive human pathogen Listeria monocytogenes senses and responds to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc13fd181373e6da5e8679ea407e575b
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-190844

Mild Stress Conditions during Laboratory Culture Promote the Proliferation of Mutations That Negatively Affect Sigma B Activity in Listeria monocytogenes

Autor: Teresa Tiensuu, Diana Gudynaite, Aoife Boyd, Francisco García-del Portillo, Duarte N. Guerreiro, Jialun Wu, Catarina M. Marinho, Jörgen Johansson, Ana H. Oliveira, Charlotte Dessaux, Conor P. O'Byrne

Publikováno v: Journal of Bacteriology
Journal of Bacteriology, American Society for Microbiology, 2020, 202 (9), ⟨10.1128/jb.00751-19⟩
J Bacteriol
Digital.CSIC. Repositorio Institucional del CSIC
instname

In Listeria monocytogenes, the full details of how stress signals are integrated into the σB regulatory pathway are not yet available. To help shed light on this question, we investigated a collection of transposon mutants that were predicted to hav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bffb864f7d03b39ddb7189260b4b2d0

Blue-Light Inhibition of Listeria monocytogenes Growth Is Mediated by Reactive Oxygen Species and Is Influenced by σ B and the Blue-Light Sensor Lmo0799

Autor: Claire Bennett, Jörgen Johansson, Kerrie NicAogáin, Teresa Tiensuu, Beth O'Donoghue, Conor P. O'Byrne, Alan J. Conneely

Publikováno v: Applied and Environmental Microbiology. 82:4017-4027

Listeria monocytogenes senses blue light via the flavin mononucleotide-containing sensory protein Lmo0799, leading to activation of the general stress response sigma factor SigB (σ B ). In this study, we investigated the physiological response of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508a60a896bea375651b1f0b4dd82f43
https://doi.org/10.1128/aem.00685-16

Caenorhabditis elegans lin-25: cellular focus, protein expression and requirement for sur-2 during induction of vulval fates

Autor: Teresa Tiensuu, Lars Nilsson, Iva Greenwald, Xiajun Li, Roy Auty, Simon Tuck

Publikováno v: Development. 125:4809-4819

Induction of vulval fates in the C. elegans hermaphrodite is mediated by a signal transduction pathway involving Ras and MAP kinase. Previous genetic analysis has suggested that two potential targets of this pathway in the vulva precursor cells are t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0f3d6f324f25093e4f83c29a566d22
https://doi.org/10.1242/dev.125.23.4809