Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Teresa Rubio-Tomás"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2860 (2024)
Pancreatic ductal adenocarcinoma (PDAC) is one of the leading causes of cancer-related death worldwide. It is commonly diagnosed in advanced stages and therapeutic interventions are typically constrained to systemic chemotherapy, which yields only mo
Externí odkaz:
https://doaj.org/article/cb674f8474914a0c972b444f2887b503
Autor:
Aadil Javed, Gianluca Malagraba, Mahdieh Yarmohammadi, Catalina M. Perelló-Reus, Carles Barceló, Teresa Rubio-Tomás
Publikováno v:
Future Pharmacology, Vol 2, Iss 3, Pp 214-237 (2022)
Mitosis entails mechanistic changes required for maintaining the genomic integrity in all dividing cells. The process is intricate and temporally and spatially regulated by the ordered series of activation and de-activation of protein kinases. The mi
Externí odkaz:
https://doaj.org/article/ba5f4ba4ac7e4352be60509ebf8cb0c6
Autor:
Catalina M. Perelló-Reus, Teresa Rubio-Tomás, Eugenia Cisneros-Barroso, Lesly Ibargüen-González, Juan José Segura-Sampedro, Rafael Morales-Soriano, Carles Barceló
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Pancreatic cancer adenocarcinoma (PDAC) is a lethal disease, with the lowest 5-years survival rate of all cancers due to late diagnosis. Despite the advance and success of precision oncology in gastrointestinal cancers, the frequency of molecular-inf
Externí odkaz:
https://doaj.org/article/fa7bac7a314c4edc860a71341638e243
Autor:
Isabel Graupera, Laura Isus, Mar Coll, Elisa Pose, Alba Díaz, Julia Vallverdú, Teresa Rubio-Tomás, Celia Martínez-Sánchez, Patricia Huelin, Marta Llopis, Cristina Solé, Elsa Solà, Constantino Fondevila, Juan José Lozano, Pau Sancho-Bru, Pere Ginès, Patrick Aloy
Publikováno v:
JHEP Reports, Vol 4, Iss 6, Pp 100482- (2022)
Background & Aims: The molecular mechanisms driving the progression from early-chronic liver disease (CLD) to cirrhosis and, finally, acute-on-chronic liver failure (ACLF) are largely unknown. Our aim was to develop a protein network-based approach t
Externí odkaz:
https://doaj.org/article/4d279b50e65d4f14a2a246d30b4f3ba4
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2848 (2023)
Gastric cancer predominantly occurs in adenocarcinoma form and is characterized by uncontrolled growth and metastases of gastric epithelial cells. The growth of gastric cells is regulated by the action of several major cell cycle regulators including
Externí odkaz:
https://doaj.org/article/8240556d4466438398e40ce35901baaf
Oxidative Stress in Age-Related Neurodegenerative Diseases: An Overview of Recent Tools and Findings
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 131 (2023)
Reactive oxygen species (ROS) have been described to induce a broad range of redox-dependent signaling reactions in physiological conditions. Nevertheless, an excessive accumulation of ROS leads to oxidative stress, which was traditionally considered
Externí odkaz:
https://doaj.org/article/34f77faab4e347708924d61b8dbded49
Autor:
Teresa Rubio-Tomás
Publikováno v:
Heliyon, Vol 7, Iss 6, Pp e07387- (2021)
Epigenetics is an emerging field, due to its relevance in the regulation of a wide range of biological processes. The Su(Var)3–9, Enhancer-of-zeste and Trithorax (SET) and Myeloid, Nervy, and DEAF-1 (MYND) domain-containing (SMYD) proteins, named S
Externí odkaz:
https://doaj.org/article/3a22a1509279414c85760575a4a49d89
Publikováno v:
Biomolecules, Vol 12, Iss 3, p 462 (2022)
Epigenetic mechanisms are known to play a key role in cancer progression. Specifically, histone methylation involves reversible post-translational modification of histones that govern chromatin structure remodelling, genomic imprinting, gene expressi
Externí odkaz:
https://doaj.org/article/f504e329129946048cb43bafc9e2f0b1
Publikováno v:
Pathogens, Vol 10, Iss 7, p 875 (2021)
Helicobacter pylori (H. pylori) is a Gram-negative bacterium that colonizes the stomach and can induce gastric disease and intra-gastric lesions, including chronic gastritis, peptic ulcers, gastric adenocarcinoma, and mucosa-associated lymphoid tissu
Externí odkaz:
https://doaj.org/article/f034a582cce440b0bfe6ebd4e0f5a084
Publikováno v:
Clinical and Translational Oncology. 25:1594-1605
Hepatocellular carcinoma (HCC) is the prevalent form of liver cancer in adults and the fourth most common cause of cancer-related death worldwide. HCC predominantly arises in the context of cirrhosis as a result of chronic liver disease, injury and i