Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Teresa R, Wagner"'
Autor:
Desiree I. Frecot, Simone Blaess, Teresa R. Wagner, Philipp D. Kaiser, Bjoern Traenkle, Madeleine Fandrich, Meike Jakobi, Armin M. Scholz, Stefan Nueske, Nicole Schneiderhan-Marra, Cécile Gouttefangeas, Manfred Kneilling, Bernd J. Pichler, Dominik Sonanini, Ulrich Rothbauer
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
PurposeHuman OX40 (hOX40/CD134), a member of the TNF receptor superfamily, is mainly expressed on activated T lymphocytes. Triggered by its ligand OX40L (CD252), it provides costimulatory signals that support the differentiation, proliferation and lo
Externí odkaz:
https://doaj.org/article/ce3a8aa1d9c443469359f03d31106fa0
Autor:
Teresa R. Wagner, Simone Blaess, Inga B. Leske, Desiree I. Frecot, Marius Gramlich, Bjoern Traenkle, Philipp D. Kaiser, Dominik Seyfried, Sandra Maier, Amélie Rezza, Fabiane Sônego, Kader Thiam, Stefania Pezzana, Anne Zeck, Cécile Gouttefangeas, Armin M. Scholz, Stefan Nueske, Andreas Maurer, Manfred Kneilling, Bernd J. Pichler, Dominik Sonanini, Ulrich Rothbauer
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Signal-regulatory protein α (SIRPα) expressed by myeloid cells is of particular interest for therapeutic strategies targeting the interaction between SIRPα and the “don’t eat me” ligand CD47 and as a marker to monitor macrophage infiltration
Externí odkaz:
https://doaj.org/article/29efe43cd84c4093b9130cdff8fcf447
Autor:
Daniel Junker, Alex Dulovic, Matthias Becker, Teresa R. Wagner, Philipp D. Kaiser, Bjoern Traenkle, Katharina Kienzle, Stefanie Bunk, Carlotta Struemper, Helene Haeberle, Kristina Schmauder, Natalia Ruetalo, Nisar Malek, Karina Althaus, Michael Koeppen, Ulrich Rothbauer, Juliane S. Walz, Michael Schindler, Michael Bitzer, Siri Göpel, Nicole Schneiderhan-Marra
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract As global vaccination campaigns against SARS-CoV-2 proceed, there is particular interest in the longevity of immune protection, especially with regard to increasingly infectious virus variants. Neutralizing antibodies (Nabs) targeting the re
Externí odkaz:
https://doaj.org/article/65541620e8964ed78cf2db87bc1b9e1e
Autor:
Sandra Burgstaller, Teresa R. Wagner, Helmut Bischof, Sarah Bueckle, Aman Padamsey, Desiree Frecot, Philipp D. Kaiser, David Skrabak, Roland Malli, Robert Lukowski, Ulrich Rothbauer
Publikováno v:
iScience, Vol 25, Iss 9, Pp 104907- (2022)
Summary: Ion and analyte changes in the tumor microenvironment (TME) alter the metabolic activity of cancer cells, promote tumor cell growth, and impair anti-tumor immunity. Consequently, accurate determination and visualization of extracellular chan
Externí odkaz:
https://doaj.org/article/c93a87783219431f8eb4f7cb90e33442
Autor:
Matthias Becker, Alex Dulovic, Daniel Junker, Natalia Ruetalo, Philipp D. Kaiser, Yudi T. Pinilla, Constanze Heinzel, Julia Haering, Bjoern Traenkle, Teresa R. Wagner, Mirjam Layer, Martin Mehrlaender, Valbona Mirakaj, Jana Held, Hannes Planatscher, Katja Schenke-Layland, Gérard Krause, Monika Strengert, Tamam Bakchoul, Karina Althaus, Rolf Fendel, Andrea Kreidenweiss, Michael Koeppen, Ulrich Rothbauer, Michael Schindler, Nicole Schneiderhan-Marra
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Here, the authors characterize the antibody response from vaccinated (Pfizer BNT-162b2), infected and uninfected individuals against emerging variants of concern of SARS-CoV-2, finding reduced neutralization of a South African isolate. High IgG titer
Externí odkaz:
https://doaj.org/article/b1f0cfb4a3c942a594406b501e462f7e
Autor:
Funmilayo O. Fagbadebo, Philipp D. Kaiser, Katharina Zittlau, Natascha Bartlick, Teresa R. Wagner, Theresa Froehlich, Grace Jarjour, Stefan Nueske, Armin Scholz, Bjoern Traenkle, Boris Macek, Ulrich Rothbauer
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
The mitochondrial outer membrane (MOM)-anchored GTPase Miro1, is a central player in mitochondrial transport and homeostasis. The dysregulation of Miro1 in amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD) suggests that Miro1 may be
Externí odkaz:
https://doaj.org/article/5f8441813ca64fc2a5f92ee373c20e9f
Autor:
Bjoern Traenkle, Philipp D. Kaiser, Stefania Pezzana, Jennifer Richardson, Marius Gramlich, Teresa R. Wagner, Dominik Seyfried, Melissa Weldle, Stefanie Holz, Yana Parfyonova, Stefan Nueske, Armin M. Scholz, Anne Zeck, Meike Jakobi, Nicole Schneiderhan-Marra, Martin Schaller, Andreas Maurer, Cécile Gouttefangeas, Manfred Kneilling, Bernd J. Pichler, Dominik Sonanini, Ulrich Rothbauer
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The advancement of new immunotherapies necessitates appropriate probes to monitor the presence and distribution of distinct immune cell populations. Considering the key role of CD4+ cells in regulating immunological processes, we generated novel sing
Externí odkaz:
https://doaj.org/article/843af024f10946eba486517b59dfb1c6
Publikováno v:
BIOspektrum. 29:145-149
2023 marks the 30th anniversary of the discovery of single-domain antibody fragments in camelids, better known as nanobodies. This was the starting point for their tremendous success story in biomedicine. Here we highlight recent advances in the deve
Autor:
Teresa R. Wagner, Ulrich Rothbauer
Publikováno v:
Biomolecules, Vol 10, Iss 12, p 1701 (2020)
In biomedical research, there is an ongoing demand for new technologies to elucidate disease mechanisms and develop novel therapeutics. This requires comprehensive understanding of cellular processes and their pathophysiology based on reliable inform
Externí odkaz:
https://doaj.org/article/fbaf0859d4774250a4c0567309c6c25f
Autor:
Ulrich Rothbauer, Teresa R Wagner
Publikováno v:
Free Radical Biology and Medicine. 176:46-61
The identification of diagnostic and therapeutic targets requires a comprehensive understanding of cellular processes, for which advanced technologies in biomedical research are needed. The emergence of nanobodies (Nbs) derived from antibody fragment