Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Teresa Puthussery"'
Autor:
Mean-Hwan Kim, Paulo Strazza, Jr., Teresa Puthussery, Owen P. Gross, W. Rowland Taylor, Henrique von Gersdorff
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113440- (2023)
Summary: Retinal ribbon synapses undergo functional changes after eye opening that remain uncharacterized. Using light-flash stimulation and paired patch-clamp recordings, we examined the maturation of the ribbon synapse between rod bipolar cells (RB
Externí odkaz:
https://doaj.org/article/24d6cb0e30c541619bdf22a4482c8e8e
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
Cell reports. 41(2)
Midget and parasol ganglion cells (GCs) represent the major output channels from the primate eye to the brain. On-type midget and parasol GCs exhibit a higher background spike rate and thus can respond more linearly to contrast changes than their Off
Autor:
Teresa Puthussery, Colin J Chu, David R. Williams, Peter J. Murphy, William H. Merigan, Tyler Godat, William S. Fischer, Zhengyang Xu, Brittany Bateman, Juliette E. McGregor, Karteek Kunala, Jennifer M. Strazzeri, Keith Parkins
Publikováno v:
McGregor, J E, Kunala, K, Xu, Z, Murphy, P J, Godat, T, Strazzeri, J M, Bateman, B A, Fischer, W S, Parkins, K, Chu, C J, Puthussery, T, Williams, D R & Merigan, W H 2021, ' Optogenetic therapy restores retinal activity in primate for at least a year following photoreceptor ablation ', Molecular Therapy . https://doi.org/10.1016/j.ymthe.2021.09.014
All retina-based vision restoration approaches rely on the assumption that photoreceptor loss does not preclude reactivation of the remaining retinal architecture. Whether extended periods of vision loss limit the efficacy of restorative therapies at
Adapting between scotopic and photopic illumination involves switching the routing of retinal signals between rod and cone-dominated circuits. In the daytime, cone signals pass through parallel On and Off cone bipolar cells, that are sensitive to inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3acf5b48b23efe70806c846fa9cfadba
https://doi.org/10.1101/2020.05.17.100982
https://doi.org/10.1101/2020.05.17.100982
Autor:
Sarah H. Gardner, Arlene V. Drack, Sajag Bhattarai, Nikolai O. Artemyev, Vasily Kerov, Rachel O.L. Wong, Wade R. Gutierrez, Sharmon Knecht, Daniel Soh, Jussara Hagen, Amy S. Lee, Mei Ling Joiner, Teresa Puthussery, Sheila A. Baker, Takeshi Yoshimatsu, Joseph G. Laird
Publikováno v:
The Journal of Neuroscience. 38:6145-6160
α2δ-4 is an auxiliary subunit of voltage-gated Cav1.4 L-type channels that regulate the development and mature exocytotic function of the photoreceptor ribbon synapse. In humans, mutations in the CACNA2D4 gene encoding α2δ-4 cause heterogeneous f
Publikováno v:
The Journal of Neuroscience. 38:3414-3427
Silent voltage-gated potassium channel subunits (KVS) interact selectively with members of the KV2 channel family to modify their functional properties. The localization and functional roles of these silent subunits remain poorly understood. Mutation
Autor:
Lauren Renner, Xiaojie Wang, Trevor J. McGill, Lois M. A. Colgin, Samuel M. Peterson, Brandy L. Dozier, Jacqueline Gayet, Cassandra Cullin, Jonathan Stoddard, Kamm Prongay, Martha Neuringer, Betsy Ferguson, Anne D. Lewis, Teresa Puthussery
Publikováno v:
Exp Eye Res
The development of therapies for retinal disorders is hampered by a lack of appropriate animal models. Higher nonhuman primates are the only animals with retinal structure similar to humans, including the presence of a macula and fovea. However, few
Publikováno v:
eNeuro
Adapting between scotopic and photopic illumination involves switching the routing of retinal signals between rod and cone-dominated circuits. In the daytime, cone signals pass through parallel On and Off cone bipolar cells (CBCs), that are sensitive
Autor:
Vasily, Kerov, Joseph G, Laird, Mei-Ling, Joiner, Sharmon, Knecht, Daniel, Soh, Jussara, Hagen, Sarah H, Gardner, Wade, Gutierrez, Takeshi, Yoshimatsu, Sajag, Bhattarai, Teresa, Puthussery, Nikolai O, Artemyev, Arlene V, Drack, Rachel O, Wong, Sheila A, Baker, Amy, Lee
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 38(27)
α2δ-4 is an auxiliary subunit of voltage-gated Cav1.4 L-type channels that regulate the development and mature exocytotic function of the photoreceptor ribbon synapse. In humans, mutations in the CACNA2D4 gene encoding α2δ-4 cause heterogeneous f