Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Teresa Paíno"'
Autor:
Esperanza M Algarín, Andrea Díaz-Tejedor, Pedro Mogollón, Susana Hernández-García, Luis A. Corchete, Laura San-Segundo, Montserrat Martín-Sánchez, Lorena González-Méndez, Marie Schoumacher, Sebastien Banquet, Laurence Kraus-Berthier, Ioana Kloos, Alix Derreal, Ensar Halilovic, Heiko Maacke, Norma C. Gutiérrez, María-Victoria Mateos, Teresa Paíno, Mercedes Garayoa, Enrique M. Ocio
Publikováno v:
Haematologica, Vol 105, Iss 3 (2020)
Externí odkaz:
https://doaj.org/article/512f9175196b4277b36f9d7dcf905aba
Autor:
Ana-Alicia López-Iglesias, Ana B. Herrero, Marta Chesi, Laura San-Segundo, Lorena González-Méndez, Susana Hernández-García, Irena Misiewicz-Krzeminska, Dalia Quwaider, Montserrat Martín-Sánchez, Daniel Primo, Teresa Paíno, P. Leif Bergsagel, Thomas Mehrling, Marcos González-Díaz, Jesús F. San-Miguel, María-Victoria Mateos, Norma C. Gutiérrez, Mercedes Garayoa, Enrique M. Ocio
Publikováno v:
Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-14 (2017)
Abstract Background Despite recent advances in the treatment of multiple myeloma (MM), the prognosis of most patients remains poor, and resistance to traditional and new drugs frequently occurs. EDO-S101 is a novel therapeutic agent conceived as the
Externí odkaz:
https://doaj.org/article/bfebf6dd497c42b797a071d86cc0e1d4
Autor:
Esperanza M. Algarín, Dalia Quwaider, Francisco J. Campos-Laborie, Andrea Díaz-Tejedor, Pedro Mogollón, Elena Vuelta, Montserrat Martín-Sánchez, Laura San-Segundo, Lorena González-Méndez, Norma C. Gutiérrez, Ramón García-Sanz, Teresa Paíno, Javier De Las Rivas, Enrique M. Ocio, Mercedes Garayoa
Publikováno v:
Cells, Vol 10, Iss 3, p 559 (2021)
BH3-mimetics targeting anti-apoptotic proteins such as MCL-1 (S63845) or BCL-2 (venetoclax) are currently being evaluated as effective therapies for the treatment of multiple myeloma (MM). Interleukin 6, produced by mesenchymal stromal cells (MSCs),
Externí odkaz:
https://doaj.org/article/7bd7f27b907643eda8b4ac2b546d5f0a
Autor:
Susana Hernández-García, Laura San-Segundo, Lorena González-Méndez, Luis A. Corchete, Irena Misiewicz-Krzeminska, Montserrat Martín-Sánchez, Ana-Alicia López-Iglesias, Esperanza Macarena Algarín, Pedro Mogollón, Andrea Díaz-Tejedor, Teresa Paíno, Brian Tunquist, María-Victoria Mateos, Norma C Gutiérrez, Elena Díaz-Rodriguez, Mercedes Garayoa, Enrique M Ocio
Publikováno v:
Haematologica, Vol 102, Iss 12 (2017)
Kinesin spindle protein inhibition is known to be an effective therapeutic approach in several malignancies. Filanesib (ARRY-520), an inhibitor of this protein, has demonstrated activity in heavily pre-treated multiple myeloma patients. The aim of th
Externí odkaz:
https://doaj.org/article/e78ee3f2567c4e699594330a48ccd63b
Autor:
Ana-Alicia López-Iglesias, Lorena González-Méndez, Laura San-Segundo, Ana B. Herrero, Susana Hernández-García, Montserrat Martín-Sánchez, Norma C. Gutiérrez, Teresa Paíno, Pablo Avilés, María-Victoria Mateos, Jesús F. San-Miguel, Mercedes Garayoa, Enrique M. Ocio
Publikováno v:
Haematologica, Vol 102, Iss 1 (2017)
Despite new advances in multiple myeloma treatment and the consequent improvement in overall survival, most patients relapse or become refractory to treatment. This suggests that new molecules and combinations that may further inhibit important survi
Externí odkaz:
https://doaj.org/article/0431cc7d4e214155a1909b6f5466c684
Autor:
Teresa Paíno, María E Sarasquete, Bruno Paiva, Patryk Krzeminski, Laura San-Segundo, Luis A Corchete, Alba Redondo, Mercedes Garayoa, Ramón García-Sanz, Norma C Gutiérrez, Enrique M Ocio, Jesús F San-Miguel
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92378 (2014)
Despite recent advances in the treatment of multiple myeloma (MM), it remains an incurable disease potentially due to the presence of resistant myeloma cancer stem cells (MM-CSC). Although the presence of clonogenic cells in MM was described three de
Externí odkaz:
https://doaj.org/article/3ed73b7d077a49e0b8fcf3a00b27cc9c
Autor:
Irena Misiewicz-Krzeminska, María E. Sarasquete, Dalia Quwaider, Patryk Krzeminski, Fany V. Ticona, Teresa Paíno, Manuel Delgado, Andreia Aires, Enrique M. Ocio, Ramón García-Sanz, Jesús F. San Miguel, Norma C. Gutiérrez
Publikováno v:
Haematologica, Vol 98, Iss 4 (2013)
MicroRNA have been demonstrated to be deregulated in multiple myeloma. We have previously reported that miR-214 is down-regulated in multiple myeloma compared to in normal plasma cells. The functional role of miR-214 in myeloma pathogenesis was explo
Externí odkaz:
https://doaj.org/article/5307c07cef5d4d26b815bb433bff5a56
Publikováno v:
Haematologica, Vol 98, Iss 1 (2013)
Externí odkaz:
https://doaj.org/article/dca6c0abda5442dc8fa2c7778b1de4f4
Autor:
Teresa Paíno, Enrique M. Ocio, Bruno Paiva, Laura San-Segundo, Mercedes Garayoa, Norma C. Gutiérrez, M. Eugenia Sarasquete, Atanasio Pandiella, Alberto Orfao, Jesús F. San Miguel
Publikováno v:
Haematologica, Vol 97, Iss 7 (2012)
Although new therapies have doubled the survival of multiple myeloma patients, this remains an incurable disease. It has been postulated that the so-called myeloma cancer stem cells would be responsible for tumor initiation and relapse but their uneq
Externí odkaz:
https://doaj.org/article/8d9b9bce676c43d6a0187df5a4b84adc
Autor:
Enrique Colado, Teresa Paíno, Patricia Maiso, Enrique M. Ocio, Xi Chen, Stela Álvarez-Fernández, Norma C. Gutiérrez, Jesús Martín-Sánchez, Juan Flores-Montero, Laura San Segundo, Mercedes Garayoa, Diego Fernández-Lázaro, Maria-Belen Vidriales, Carlos M. Galmarini, Pablo Avilés, Carmen Cuevas, Atanasio Pandiella, Jesús F. San-Miguel
Publikováno v:
Haematologica, Vol 96, Iss 5 (2011)
Background Although the majority of patients with acute myeloid leukemia initially respond to conventional chemotherapy, relapse is still the leading cause of death, probably because of the presence of leukemic stem cells that are insensitive to curr
Externí odkaz:
https://doaj.org/article/86c04c8ca31e4c4e9ae165d0cff57a91