Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Teresa Olczak"'
Autor:
Michał Śmiga, Teresa Olczak
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
IntroductionPorphyromonas gingivalis and Porphyromonas endodontalis belong to the Bacteroidota phylum. Both species inhabit the oral cavity and can be associated with periodontal diseases. To survive, they must uptake heme from the host as an iron an
Externí odkaz:
https://doaj.org/article/a9ba7f6d81fb4b74bf98d7d491b5a94a
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 3 (2024)
ABSTRACTPorphyromonas gingivalis strains exhibit different phenotypes in vitro, different virulence potential in animal models, and different associations with human diseases, with strains classified as virulent/more virulent (e.g., A7436 and W83) or
Externí odkaz:
https://doaj.org/article/473cfd776aa84558899d3fa9e251c3a1
Autor:
Michał Śmiga, Klaudia Siemińska, Soraya C. Trindade, Isaac S. Gomes-Filho, Ellen K. Nobre dos Santos, Teresa Olczak
Publikováno v:
Journal of Oral Microbiology, Vol 15, Iss 1 (2023)
ABSTRACTAims Hemophore-like proteins sequester heme from host hemoproteins. We aimed to determine whether the host immune system can recognize not only Porphyromonas gingivalis HmuY but also its homologs expressed by other periodontopathogens, and ho
Externí odkaz:
https://doaj.org/article/f407d4834c1c4156996b698e107db899
Publikováno v:
BMC Microbiology, Vol 19, Iss 1, Pp 1-16 (2019)
Abstract Background Porphyromonas gingivalis is considered a keystone pathogen responsible for chronic periodontitis. Although several virulence factors produced by this bacterium are quite well characterized, very little is known about regulatory me
Externí odkaz:
https://doaj.org/article/75c18a6e2187411b9b919b8f03d50bcf
Autor:
Ellen Karla Nobre dos Santos-Lima, Kizzes Araújo Paiva Andrade Cardoso, Patrícia Mares de Miranda, Ana Carla Montino Pimentel, Paulo Cirino de Carvalho-Filho, Yuri Andrade de Oliveira, Lília Ferreira de Moura-Costa, Teresa Olczak, Isaac Suzart Gomes-Filho, Roberto José Meyer, Márcia Tosta Xavier, Soraya Castro Trindade
Publikováno v:
AMB Express, Vol 9, Iss 1, Pp 1-11 (2019)
Abstract Porphyromonas gingivalis (Pg) is one of the main pathogens in chronic periodontitis (CP). Studies on the immunogenicity of its virulence factors may contribute to understanding the host response to infection. The present study aimed to use i
Externí odkaz:
https://doaj.org/article/0693fab0780c45109768417d8fba081c
Publikováno v:
Molecules, Vol 27, Iss 5, p 1703 (2022)
To acquire heme, Porphyromonas gingivalis uses a hemophore-like protein (HmuY). HmuY sequesters heme from host hemoproteins or heme-binding proteins produced by cohabiting bacteria, and delivers it to the TonB-dependent outer-membrane receptor (HmuR)
Externí odkaz:
https://doaj.org/article/f1c8a172d9764e5ba2a31999996f8095
Autor:
Michał Śmiga, John W. Smalley, Paulina Ślęzak, Jason L. Brown, Klaudia Siemińska, Rosalind E. Jenkins, Edwin A. Yates, Teresa Olczak
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 12084 (2021)
The non-enzymatic addition of glucose (glycation) to circulatory and tissue proteins is a ubiquitous pathophysiological consequence of hyperglycemia in diabetes. Given the high incidence of periodontitis and diabetes and the emerging link between the
Externí odkaz:
https://doaj.org/article/d0c6fa6669a445a9babe3ca49a032b35
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
Porphyromonas gingivalis, a keystone pathogen of chronic periodontitis, uses ferric uptake regulator homolog (PgFur) to regulate production of virulence factors. This study aimed to characterize PgFur protein in regard to its structure-function relat
Externí odkaz:
https://doaj.org/article/b6c6edb995da4d0daaa10ac9acf00fff
Autor:
Paulo C. Carvalho-Filho, Lilia F. Moura-Costa, Ana C. M. Pimentel, Mabel P. P. Lopes, Sibelle A. Freitas, Patrícia M. Miranda, Ryan S. Costa, Camila A. V. Figueirêdo, Roberto Meyer, Isaac S. Gomes-Filho, Teresa Olczak, Márcia T. Xavier, Soraya C. Trindade
Publikováno v:
Mediators of Inflammation, Vol 2019 (2019)
This study aimed at evaluating the transcriptional profile of apoptosis-related genes after in vitro stimulation of peripheral blood mononuclear cells (PBMCs) derived from individuals with periodontitis (P) and healthy nonperiodontitis (NP) control s
Externí odkaz:
https://doaj.org/article/7a810b0c49ff41edabcd22f58beb5edc
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2237 (2021)
Human oral and gut microbiomes are crucial for maintenance of homeostasis in the human body. Porphyromonas gingivalis, the key etiologic agent of chronic periodontitis, can cause dysbiosis in the mouth and gut, which results in local and systemic inf
Externí odkaz:
https://doaj.org/article/c5a06bd9c42d43eb94b390e209c33d70