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pro vyhledávání: '"Teresa Monteith"'
Autor:
William C. Hahn, Rosalie C. Sears, Christopher M. Counter, Joseph R. Nevins, Shirish Shenolikar, Takafumi Uchida, Giovanni Ivaldi, Anthony R. Means, Melissa Cunningham, Elizabeth S. Yeh, Dawn Chasse, Teresa Monteith, P. Todd Stukenberg, Hugh Arnold
Publikováno v:
Nature Cell Biology. 6:308-318
The stability of c-Myc is regulated by multiple Ras effector pathways. Phosphorylation at Ser 62 stabilizes c-Myc, whereas subsequent phosphorylation at Thr 58 is required for its degradation. Here we show that Ser 62 is dephosphorylated by protein p