Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Teresa M. Kubiak"'
Autor:
Alan R. Friedman, Teresa M. Kubiak, Ronald T. Borchardt, Cynthia L. Stevenson, Mary E. Donlan
Publikováno v:
International Journal of Peptide and Protein Research. 42:497-503
The objective of this study was to determine whether the rates of deamidation of Asn8 in selected growth hormone releasing factor (GRF) analogs were related to the peptide's secondary structures in solution. Bovine or human [Leu27]GRF(1-32)NH2 (both
Autor:
Jerry W. Bowman, Teresa M. Kubiak, Susan C. Nulf, Marjorie R. Zantello, Martha J. Larsen, David E. Lowery, Katherine J. Burton, Tomislav Modric
Publikováno v:
Journal of Biological Chemistry. 278:33724-33729
Natural variations of wild Caenorhabditis elegans isolates having either Phe-215 or Val-215 in NPR-1, a putative orphan neuropeptide Y-like G protein-coupled receptor, result in either “social” or “solitary” feeding behaviors (de Bono, M., an
Publikováno v:
Biochemical and Biophysical Research Communications. 301:456-459
KHEYLRF-NH 2 (AF2) is the most abundant FMRFamide-related peptide (FaRP) in Ascaris suum and also in many other parasitic and free-living nematodes. The AF2 abundance in the highly diverse nematodes and its potent and profound effects on the neuromus
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1164:252-260
The literature reported DPP-IV substrate specificity includes oligopeptides with a penultimate Pro, Hyp or Ala residue. Bovine GRF is a substrate for DPP-IV and is rapidly degraded by the enzyme via removal of its N-terminal Tyr-Ala. Incubation of se
Autor:
M. C. Goodwin, A. R. Friedman, R. M. Hillman, W. H. Claflin, A. K. Ichhpurani, G. R. Alaniz, Cleary Dl, Teresa M. Kubiak, C. R. Kelly, R. A. Martin
Publikováno v:
Journal of Medicinal Chemistry. 36:888-897
In order to prepare GRF analogs with high activity in vivo, a strategy was undertaken to stabilize the peptide to dipeptidylpeptidase IV (DPP-IV), a protease found in plasma which inactivates native human and bovine GRF by cleavage of the Ala2-Asp3 b
Autor:
Martha J. Larsen, Timothy G. Geary, Aaron G. Maule, Hanan Omar, Judith E. Humphries, Tim A. Day, Teresa M. Kubiak, Michael J. Kimber
Publikováno v:
International journal for parasitology. 37(7)
We report the characterisation of the first neuropeptide receptor from the phylum Platyhelminthes, an early-diverging phylum which includes a number of important human and veterinary parasites. The G protein-coupled receptor (GPCR) was identified fro
Autor:
Darrell R. Thomsen, Lisa A. Adams, Rolf F. Kletzien, John E. Bleasdale, Michael L. Swanson, Peter K. W. Harris, Roger F. Drong, Che-Shen C. Tomich, Teresa M. Kubiak
Publikováno v:
Peptides for the New Millennium ISBN: 0792364457
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bffea4a2e64ccd5168415540192b2e6
https://doi.org/10.1007/0-306-46881-6_213
https://doi.org/10.1007/0-306-46881-6_213
Autor:
Teresa M. Kubiak, Timothy G. Geary
Publikováno v:
Trends in pharmacological sciences. 26(2)
Despite a simple nervous system, the free-living nematode Caenorhabditis elegans exhibits complex behaviors. The identification of peptide ligands for a G-protein-coupled receptor (GPCR) has provided insight into the neuronal circuitry involved in th
Autor:
Martha J. Larsen, David E. Lowery, Susan C. Nulf, Marjorie R. Zantello, Teresa M. Kubiak, Jerry W. Bowman
Publikováno v:
The Journal of biological chemistry. 278(43)
This report describes the cloning and functional annotation of a Caenorhabditis elegans orphan G-protein-coupled receptor (GPCR) (C10C6.2) as a receptor for the FMRFamide-related peptides (FaRPs) encoded on the flp15 precursor gene, leading to the re
Autor:
Marjorie R. Zantello, Erich W. Zinser, Teresa M. Kubiak, Katherine J. Burton, Valdin G. Smith, Martha J. Larsen, David E. Lowery
Publikováno v:
Peptides: The Wave of the Future ISBN: 9789401039055
The type A allatostatins (ASTs) are a group of insect peptides with a common C-terminal motif F/YXFGL-NH2. ASTs control visceral muscle contractions and, indirectly, insect larval development, sexual maturation and reproduction by inhibiting juvenile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9b2764b7a1214afc0a29bb01fbea1ba
https://doi.org/10.1007/978-94-010-0464-0_423
https://doi.org/10.1007/978-94-010-0464-0_423