Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Teresa M. Calonge"'
Autor:
Claudia Tapia-Alveal1 claudia.tapia-alveal@mssm.edu, Teresa M Calonge1,2 tematge@hotmail.com, O'Connell, Matthew J.1 matthew.oconnell@mssm.edu
Publikováno v:
Cell Division. 2009, Vol. 4, p1-7. 7p. 3 Diagrams, 1 Chart.
Publikováno v:
Genetics. 185:81-93
The G2 DNA damage checkpoint inhibits Cdc2 and mitotic entry through the dual regulation of Wee1 and Cdc25 by the Chk1 effector kinase. Upregulation of Chk1 by mutation or overexpression bypasses the requirement for upstream regulators or DNA damage
Publikováno v:
Journal of Biological Chemistry. 282:20388-20394
We describe two RING finger proteins in the fission yeast Schizosaccharomyces pombe, Rfp1 and Rfp2. We show that these proteins function redundantly in DNA repair. Rfp1 was isolated as a Chk1-interacting protein in a two-hybrid screen and has high am
Publikováno v:
Molecular Microbiology. 47:507-518
Schizosaccharomyces pombe Rho1p regulates (1,3)beta-d-glucan synthesis and is required for cell integrity maintenance and actin cytoskeleton organization, but nothing is known about the regulation of this protein. At least nine different S. pombe gen
Autor:
Satoshi Katayama, Manuel Arellano, Kentaro Nakano, Takashi Toda, Ritsuko Arai, Pilar Pérez, Teresa M. Calonge, Issei Mabuchi
Publikováno v:
Scopus-Elsevier
Schizosaccharomyces pombe rho1+andrho2+genes are involved in the control of cell morphogenesis, cell integrity, and polarization of the actin cytoskeleton. Although both GTPases interact with each of the twoS. pombe protein kinase C homologues, Pck1p
Autor:
Angeles Duran, Pilar Pérez, Pedro M. Coll, María Henar Valdivieso, Teresa M. Calonge, Manuel Arellano
Publikováno v:
Scopus-Elsevier
Digital.CSIC. Repositorio Institucional del CSIC
instname
Europe PubMed Central
Digital.CSIC. Repositorio Institucional del CSIC
instname
Europe PubMed Central
Schizosaccharomyces pombe rho1+ is required for maintenance of cell integrity and polarization of the actin cytoskeleton. However, no other effector besides the (1,3)β-D-glucan synthase enzyme has been identified in S. pombe. We have further inves
Publikováno v:
DNA repair. 7(2)
In response to DNA damage, cells activate checkpoints to delay cell cycle progression and allow time for completion of DNA repair before commitment to S-phase or mitosis. During G2, many proteins collaborate to activate Chk1, an effector protein kina
Activation of the Chk1 protein kinase by DNA damage enforces a checkpoint that maintains Cdc2 in its inactive, tyrosine-15 (Y15) phosphorylated state. Chk1 downregulates the Cdc25 phosphatases and concomitantly upregulates the Wee1 kinases that contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dddd0ab0e6f3f89d0e0da7e7769e94c6
https://europepmc.org/articles/PMC1569782/
https://europepmc.org/articles/PMC1569782/
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
The Rho family of GTPases is present in all eukaryotic cells from yeast to mammals; they are regulators in signaling pathways that control actin organization and morphogenetic processes. In yeast, Rho GTPases are implicated in cell polarity processes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1034fd4246e471bba87a2b1d29b38287
http://hdl.handle.net/10261/5159
http://hdl.handle.net/10261/5159
Autor:
Teresa M. Calonge, Pilar Pérez
Publikováno v:
Journal of biochemistry. 132(4)
The mammalian protein kinase C (PKC) superfamily plays regulatory roles in many different cellular processes. However, due to the many members that exist in cells, it is very complicated to present experimental evidence of the particular function of