Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Teresa M Holm"'
Autor:
Richard W Naylor, Charles N J McGhee, Chad A Cowan, Alan J Davidson, Teresa M Holm, Trevor Sherwin
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165464 (2016)
Corneal diseases such as keratoconus represent a relatively common disorder in the human population. However, treatment is restricted to corneal transplantation, which only occurs in the most advanced cases. Cell based therapies may offer an alternat
Externí odkaz:
https://doaj.org/article/70979c0d66714540a41233eeb30982c9
Autor:
Veronika Sander, Aneta Przepiorski, Amanda E. Crunk, Neil A. Hukriede, Teresa M. Holm, Alan J. Davidson
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100150- (2020)
Summary: Kidney organoids represent a physiologically advanced model for studying the mechanisms of kidney development and disease. Here, we describe a simple two-step protocol for the differentiation of human pluripotent stem cells into kidney organ
Externí odkaz:
https://doaj.org/article/2781ad0fc39e463ebce730d990f53b97
Autor:
Aneta Przepiorski, Veronika Sander, Tracy Tran, Jennifer A. Hollywood, Brie Sorrenson, Jen-Hsing Shih, Ernst J. Wolvetang, Andrew P. McMahon, Teresa M. Holm, Alan J. Davidson
Publikováno v:
Stem Cell Reports, Vol 11, Iss 2, Pp 470-484 (2018)
Summary: Kidney organoids made from pluripotent stem cells have the potential to revolutionize how kidney development, disease, and injury are studied. Current protocols are technically complex, suffer from poor reproducibility, and have high reagent
Externí odkaz:
https://doaj.org/article/a65d691acdd94428962d7b33206bdeee
Publikováno v:
New Zealand Medical Student Journal.
Autor:
Aneta Przepiorski, Hao-Han Chang, Jen-Hsing Shih, Peter R. Shepherd, Jin Kyo Oh, Rachel C. Dodd, Veronika Sander, Teresa M. Holm, Janak de Zoysa, Jennifer A. Hollywood, Alan J. Davidson, Brie Sorrenson
Publikováno v:
Journal of the Royal Society of New Zealand. 52:54-67
We aimed to generate human induced pluripotent stem cell (iPSC) lines from New Zealand donors. These lines are the first to be generated in New Zealand. Human dermal fibroblasts were collected from two individual donors and reprogrammed with the huma
Autor:
Aneta Przepiorski, Veronika Sander, Alan J. Davidson, Neil A. Hukriede, Teresa M. Holm, Amanda E. Crunk
Publikováno v:
J Vis Exp
Kidney organoids generated from hPSCs have provided an unlimited source of renal tissue. Human kidney organoids are an invaluable tool for studying kidney disease and injury, developing cell-based therapies, and testing new therapeutics. For such app
Autor:
Amanda E. Crunk, Alan J. Davidson, Aneta Przepiorski, Veronika Sander, Teresa M. Holm, Neil A. Hukriede
Publikováno v:
STAR Protocols
STAR Protocols, Vol 1, Iss 3, Pp 100150-(2020)
STAR Protocols, Vol 1, Iss 3, Pp 100150-(2020)
Summary Kidney organoids represent a physiologically advanced model for studying the mechanisms of kidney development and disease. Here, we describe a simple two-step protocol for the differentiation of human pluripotent stem cells into kidney organo
Autor:
Randall F. D'Souza, Sreevalsan Sreebhavan, Ernst J. Wolvetang, Aneta Przepiorski, Jennifer A. Hollywood, Alan J. Davidson, Patrick T. Harrison, Teresa M. Holm
Publikováno v:
J Am Soc Nephrol
BACKGROUND: Mutations in CTNS-a gene encoding the cystine transporter cystinosin-cause the rare, autosomal, recessive, lysosomal-storage disease cystinosis. Research has also implicated cystinosin in modulating the mTORC1 pathway, which serves as a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fe3fc47788de8618014506d0c923981
https://europepmc.org/articles/PMC7217405/
https://europepmc.org/articles/PMC7217405/
Autor:
Tracy S. Tran, Ernst J. Wolvetang, Aneta Przepiorski, Veronika Sander, Brie Sorrenson, Andrew P. McMahon, Jen-Hsing Shih, Teresa M. Holm, Jennifer A. Hollywood, Alan J. Davidson
Publikováno v:
Stem Cell Reports, Vol 11, Iss 2, Pp 470-484 (2018)
Stem Cell Reports
Stem Cell Reports
Summary Kidney organoids made from pluripotent stem cells have the potential to revolutionize how kidney development, disease, and injury are studied. Current protocols are technically complex, suffer from poor reproducibility, and have high reagent
Autor:
Jennifer A. Hollywood, Alan J. Davidson, Patrick T. Harrison, Aneta Przepiorski, Ernst J. Wolvetang, Teresa M. Holm
Cystinosis is a lysosomal storage disease caused by mutations inCTNS, encoding a cystine transporter, and in its severest form is characterized by cystine accumulation, renal proximal tubule dysfunction and kidney failure. Cystinosis is treated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcd1cf607d5a06ab82abff785b661005