Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Teresa L. Tinder"'
Autor:
Pinku Mukherjee, Sandra J. Gendler, Yong Y. Lee, Sun-Il Hwang, Jorge Schettini, Mahnaz Sahraei, Teresa L. Tinder, Lopamudra D. Roy, Jennifer M. Curry, Dahlia M. Besmer
Supplementary Figure Legend from Pancreatic Ductal Adenocarcinoma Mice Lacking Mucin 1 Have a Profound Defect in Tumor Growth and Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d42fcce0f1fa83640baa62f8d9a885fd
https://doi.org/10.1158/0008-5472.22387577.v1
https://doi.org/10.1158/0008-5472.22387577.v1
Autor:
Pinku Mukherjee, Sandra J. Gendler, Yong Y. Lee, Sun-Il Hwang, Jorge Schettini, Mahnaz Sahraei, Teresa L. Tinder, Lopamudra D. Roy, Jennifer M. Curry, Dahlia M. Besmer
Supplementary Figure 1 from Pancreatic Ductal Adenocarcinoma Mice Lacking Mucin 1 Have a Profound Defect in Tumor Growth and Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e834d2aad0301e47ddc74b6955fe947
https://doi.org/10.1158/0008-5472.22387580
https://doi.org/10.1158/0008-5472.22387580
Autor:
Nicholas Helle, Stephanie F. Williams, Varun Maher, Michelle Kassner, Gerri Ortiz, Stephen C. Logie, Chao Sima, Mark Miglarese, Tassilo Hornung, Matthew Rosenow, Perrin Mok, David Spetzler, Heather A. O'Neill, Teresa L. Tinder
Publikováno v:
Cancer Research. 80:5165-5165
Identification of novel biomarkers and drug targets for colorectal cancer remains a critically unmet medical need. Target identification has historically been driven by preclinical models which poorly recapitulate the complex biology of human cancers
Autor:
Yong Y Lee, Lopamudra Das Roy, Dahlia M. Besmer, Sun-Il Hwang, Jorge Schettini, Jennifer M. Curry, Mahnaz Sahraei, Sandra J. Gendler, Pinku Mukherjee, Teresa L. Tinder
Publikováno v:
Cancer Research. 71:4432-4442
MUC1 is overexpressed and aberrantly glycosylated in more than 60% of pancreatic ductal adenocarcinomas. The functional role of MUC1 in pancreatic cancer has yet to be fully elucidated due to a dearth of appropriate models. In this study, we have gen
Autor:
Amanda Maree Walmsley, M. Lucrecia Alvarez, Sandra J. Gendler, Hugh S. Mason, Julia Pinkhasov, Pinku Mukherjee, Teresa L. Tinder, Latha B. Pathangey
Publikováno v:
Cancer Immunology, Immunotherapy. 59:1801-1811
Since epithelial mucin 1 (MUC1) is associated with several adenocarcinomas at the mucosal sites, it is pertinent to test the efficacy of a mucosally targeted vaccine formulation. The B subunit of the Vibrio cholerae cholera toxin (CTB) has great pote
Autor:
Durai B. Subramani, Giovanni De Petris, Million Arefayene, Todd C. Skaar, Pinku Mukherjee, Judy M. Bradley, Teresa L. Tinder, Gargi D. Basu
Publikováno v:
The Journal of Immunology. 182:216-224
With a 5-year survival rate of
Autor:
Arefayene Million, Jorge Schettini, Judy M. Bradley, Durai B. Subramani, Pinku Mukherjee, Todd C. Skaar, Teresa L. Tinder, Gargi D. Basu
Publikováno v:
The Journal of Immunology. 181:3116-3125
MUC1, a membrane tethered mucin glycoprotein, is overexpressed and aberrantly glycosylated in >80% of human ductal pancreatic adenocarcinoma. However, the role of MUC1 in pancreatic cancer has been elusive, partly due to the lack of an appropriate mo
Autor:
J.B. Bradley, Emmanuel T. Akporiaye, Pinku Mukherjee, Latha B. Pathangey, Gargi D. Basu, Sandra J. Gendler, Teresa L. Tinder
Publikováno v:
Vaccine. 25:1607-1618
A MUC1-based vaccine was used in a preclinical model of colon cancer. The trial was conducted in a MUC1-tolerant immune competent host injected with MC38 colon cancer cells expressing MUC1. The vaccine included: MHC class I-restricted MUC1 peptides,
Autor:
Barbara A. Pockaj, Gargi D. Basu, Christine L. Hattrup, Teresa L. Tinder, Tony Tu, Pinku Mukherjee, Judy M. Bradley
Publikováno v:
The Journal of Immunology. 177:2391-2402
We report that administration of celecoxib, a specific cyclooxygenase-2 (COX-2) inhibitor, in combination with a dendritic cell-based cancer vaccine significantly augments vaccine efficacy in reducing primary tumor burden, preventing metastasis, and
Autor:
Gargi D. Basu, Latha B. Pathangey, Teresa L. Tinder, Michelle LaGioia, Sandra J. Gendler, Pinku Mukherjee
Publikováno v:
Molecular Cancer Research. 2:632-642
Cyclooxygenase-2 (COX-2) inhibitors are rapidly emerging as a new generation of therapeutic drug in combination with chemotherapy or radiation therapy for the treatment of cancer. The mechanisms underlying its antitumor effects are not fully understo