Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Teresa L. Stackhouse"'
Autor:
Allison J. Schaser, Teresa L. Stackhouse, Leah J. Weston, Patrick C. Kerstein, Valerie R. Osterberg, Claudia S. López, Dennis W. Dickson, Kelvin C. Luk, Charles K. Meshul, Randall L. Woltjer, Vivek K. Unni
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-23 (2020)
Abstract It is necessary to develop an understanding of the specific mechanisms involved in alpha-synuclein aggregation and propagation to develop disease modifying therapies for age-related synucleinopathies, including Parkinson’s disease and Deme
Externí odkaz:
https://doaj.org/article/6b5adfc66b214f258b9f18ae019b793d
Autor:
Zhenzhou Li, Heather L. McConnell, Teresa L. Stackhouse, Martin M. Pike, Wenri Zhang, Anusha Mishra
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Neurovascular coupling, the process by which neuronal activity elicits increases in the local blood supply, is impaired in stroke patients in brain regions outside the infarct. Such impairment may contribute to neurological deterioration over time, b
Externí odkaz:
https://doaj.org/article/c7eaccd7ab43402384337a43bbf111d8
Autor:
Teresa L. Stackhouse, Anusha Mishra
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Neurovascular coupling is a crucial mechanism that matches the high energy demand of the brain with a supply of energy substrates from the blood. Signaling within the neurovascular unit is responsible for activity-dependent changes in cerebral blood
Externí odkaz:
https://doaj.org/article/9c12bdecb46146a98843d88955b137fb
Autor:
Leah J. Weston, Zoe T. Cook, Teresa L. Stackhouse, Mehtab K. Sal, Baergen I. Schultz, Zachary J.C. Tobias, Valerie R. Osterberg, Nicole L. Brockway, Saheli Pizano, Greta Glover, Tamily A. Weissman, Vivek K. Unni
Publikováno v:
Neurobiology of Disease, Vol 152, Iss , Pp 105291- (2021)
Abnormal aggregation of the α-synuclein protein is a key molecular feature of Parkinson's disease and other neurodegenerative diseases. The precise mechanisms that trigger α-synuclein aggregation are unclear, and it is not known what role aggregati
Externí odkaz:
https://doaj.org/article/fafe557367834afcb01b5d6e4c898ab3
Publikováno v:
Neurophotonics. 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d7b9f3210bee09bef4c6f28cf58e445
https://doi.org/10.1117/1.nph.9.3.031913
https://doi.org/10.1117/1.nph.9.3.031913
Autor:
Randall L. Woltjer, Claudia S. López, Charles K. Meshul, Allison J. Schaser, Teresa L. Stackhouse, Kelvin C. Luk, Valerie R. Osterberg, Leah J. Weston, Vivek K. Unni, Patrick C. Kerstein, Dennis W. Dickson
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-23 (2020)
Acta Neuropathologica Communications
Acta Neuropathologica Communications
It is necessary to develop an understanding of the specific mechanisms involved in alpha-synuclein aggregation and propagation to develop disease modifying therapies for age-related synucleinopathies, including Parkinson’s disease and Dementia with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c59abb172eb7bcb9458177067e51bb7
http://link.springer.com/article/10.1186/s40478-020-01026-0
http://link.springer.com/article/10.1186/s40478-020-01026-0
Autor:
Martin M. Pike, Heather L. McConnell, Zhen-Zhou Li, Anusha Mishra, Teresa L. Stackhouse, Wenri Zhang
Neurovascular coupling, the process by which neuronal activity elicits increases in the local blood supply, is impaired in stroke patients in brain regions outside the infarct. Such impairment may contribute to neurological deterioration over time, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a03c957615f8a43f02ceb75363b424a
https://doi.org/10.1101/2021.08.25.457547
https://doi.org/10.1101/2021.08.25.457547
Autor:
Amanda K. McCullough, Sydney Weber Boutros, Tamily A. Weissman, Randall L. Woltjer, Colin M. Wakeham, Sydney E. Dent, Valerie R. Osterberg, Jacob Raber, Esteban Luna, Nichole Owen, Leah J. Weston, Kelvin C. Luk, Vivek K. Unni, Allison J. Schaser, Teresa L. Stackhouse
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-19 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-19 (2019)
Alpha-synuclein is a presynaptic protein that forms abnormal cytoplasmic aggregates in Lewy body disorders. Although nuclear alpha-synuclein localization has been described, its function in the nucleus is not well understood. We demonstrate that alph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05c9023a05ee8cb512083e9305cb95a6
https://doi.org/10.1038/s41598-019-47227-z
https://doi.org/10.1038/s41598-019-47227-z
Autor:
Kateri J. Spinelli, Vivek K. Unni, Sydney Weber Boutros, Jacob Raber, Tamily A. Weissman, Elizabeth P. Rose, Valerie R. Osterberg, Leah J. Weston, Kelvin C. Luk, Teresa L. Stackhouse
Publikováno v:
The Journal of Biological Chemistry
Phosphorylation of alpha-synuclein at serine-129 is an important marker of pathologically relevant, aggregated forms of the protein in several important human diseases, including Parkinson's disease, Dementia with Lewy bodies, and Multiple system atr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b5a60d3f4eb0659cd36e5c38d770ac2
https://doi.org/10.1016/j.jbc.2021.100273
https://doi.org/10.1016/j.jbc.2021.100273