Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Teresa L. Squire"'
Autor:
Hiroaki Matsunami, Nicholas W. Plummer, Douglas A. Marchuk, Sudha Srinivasan, Jon S. Zawistowski, Elizabeth Huang, Laura P. Hale, Teresa L. Squire
Publikováno v:
Mammalian Genome. 17:119-128
Cerebral cavernous malformations are vascular defects of the central nervous system consisting of clusters of dilated vessels that are subject to frequent hemorrhaging. The genes mutated in three forms of autosomal dominant cerebral cavernous malform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cbc40d2120b0d3aa82dcc509e308e9b
https://doi.org/10.1007/s00335-005-0098-8
https://doi.org/10.1007/s00335-005-0098-8
Autor:
Teresa L. Squire, Matthew T. Andrews
Publikováno v:
Physiological Genomics. 16:119-130
Pancreatic triacylglycerol lipase ( PTL) is expressed in novel locations during hibernation in the thirteen-lined ground squirrel ( Spermophilus tridecemlineatus). PTL cDNAs isolated from two of these locations, heart and white adipose tissue (WAT),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::569251038daef8aace91f524eddf2858
https://doi.org/10.1152/physiolgenomics.00167.2002
https://doi.org/10.1152/physiolgenomics.00167.2002
Publikováno v:
Proceedings of the National Academy of Sciences. 95:8392-8397
Hibernation is a physiological adaptation characterized by dramatic decreases in heart rate, body temperature, and metabolism, resulting in long-term dormancy. Hibernating mammals survive for periods up to 6 mo in the absence of food by minimizing ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d484ec919ad479dbbc3eea12620cd4a5
https://doi.org/10.1073/pnas.95.14.8392
https://doi.org/10.1073/pnas.95.14.8392
Publikováno v:
Physiological genomics. 16(1)
Thirteen-lined ground squirrels ( Spermophilus tridecemlineatus) exploit the low-temperature activity of pancreatic triacylglycerol lipase (PTL) during hibernation. Lipolytic activity at body temperatures associated with hibernation was examined usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c46fdb31b49625f3258dd7af85bdb02d
https://pubmed.ncbi.nlm.nih.gov/14583599
https://pubmed.ncbi.nlm.nih.gov/14583599
Publikováno v:
Human molecular genetics.
Advances in our understanding of fundamental biological processes can be made by the analysis of defects manifested in inherited diseases. The genes responsible for these genetic syndromes often encode proteins that act at critical points of the path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b80caf0cd66577742965ece09ae08624
https://pubmed.ncbi.nlm.nih.gov/12668602
https://pubmed.ncbi.nlm.nih.gov/12668602
Coordinate expression of the PDK4 gene: a means of regulating fuel selection in a hibernating mammal
Publikováno v:
Physiological genomics. 8(1)
Hibernation in mammals requires a metabolic shift away from the oxidation of carbohydrates and toward the combustion of stored fatty acids as the primary source of energy during torpor. A key element involved in this fuel selection is pyruvate dehydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acf4314828b30115396c5daf0ac91d34
https://pubmed.ncbi.nlm.nih.gov/11842125
https://pubmed.ncbi.nlm.nih.gov/11842125
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 281(4)
Hibernating mammals can survive several months without feeding by limiting their carbohydrate catabolism and using triacylglycerols stored in white adipose tissue (WAT) as their primary source of fuel. Here we show that a lipolytic enzyme normally fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7eae0b071cd0fb6876ccc38a49fc28b
https://pubmed.ncbi.nlm.nih.gov/11557627
https://pubmed.ncbi.nlm.nih.gov/11557627
Autor:
Teresa L. Squire, Matthew T. Andrews
Publikováno v:
Life in the Cold ISBN: 9783642086823
During hibernation, mammals rely heavily on lipid stores to provide the fuel necessary to survive the winter. Pyruvate dehydrogenase kinase isozyme 4 (PDK-4) plays a key role in gating carbohydrate catabolism and allowing the switch to lipid metaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4721a1cd405619ce66aacae3df623edd
https://doi.org/10.1007/978-3-662-04162-8_35
https://doi.org/10.1007/978-3-662-04162-8_35
