Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Teresa K. Aman"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Sea urchin hyperpolarization-activated cyclic nucleotide-gated (spHCN) ion channels channels are activated by membrane hyperpolarization instead of depolarization and undergo inactivation with hyperpolarization. Here authors apply transition metal io
Externí odkaz:
https://doaj.org/article/87335df92b7c4bdb83eb77f703536c2b
Pacemaker hyperpolarization-activated cyclic nucleotide-gated (HCN) ion channels exhibit a reversed voltage-dependent gating, activating by membrane hyperpolarization instead of depolarization. Sea urchin HCN (spHCN) channels also undergo an inactiva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abe34d3501b61b81c67a10c535ef0b18
https://doi.org/10.1101/2021.01.06.425635
https://doi.org/10.1101/2021.01.06.425635
Publikováno v:
The Journal of General Physiology
A novel method is presented to measure short distances in cell plasma membranes using transition metal ion FRET with metal ions bound to introduced sites in the membrane.
Biological membranes are complex assemblies of lipids and proteins that se
Biological membranes are complex assemblies of lipids and proteins that se
Publikováno v:
The Journal of Neuroscience. 33:4976-4987
Na channels that generate resurgent current express an intracellular endogenous open-channel blocking protein, whose rapid binding upon depolarization and unbinding upon repolarization minimizes fast and slow inactivation. Na channels also bind exoge
Publikováno v:
Biophysical Journal. 110(3)
We have previously shown that a histidine (H420) in the first intracellular helix (A’ helix) of cyclic nucleotide-gated (CNGA1) channels is involved in potentiation of CNGA1 currents by transition metal ions. The binding of transition metals stabil
Autor:
Teresa K. Aman, Indira M. Raman
Publikováno v:
The Journal of Neuroscience. 30:5629-5634
Voltage-gated Na channels of cerebellar Purkinje neurons express an endogenous open-channel blocking protein. This blocker binds channels at positive potentials and unbinds at negative potentials, generating a resurgent Na current and permitting rapi
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 320:376-385
The dorsal raphe (DR) receives a prominent dopamine (DA) input that has been suggested to play a key role in the regulation of central serotoninergic transmission. DA is known to directly depolarize DR serotonin neurons, but the underlying mechanisms
Autor:
William N. Zagotta, Teresa K. Aman
Publikováno v:
Biophysical Journal. 112:249a
Publikováno v:
The Journal of biological chemistry. 289(27)
Protein kinase A (PKA) enhances synaptic plasticity in the central nervous system by increasing NMDA receptor current amplitude and Ca(2+) flux in an isoform-dependent yet poorly understood manner. PKA phosphorylates multiple residues on GluN1, GluN2
Autor:
Kelly A. Aromolaran, R. Suzanne Zukin, C. Geoffrey Lau, Gabriela K. Popescu, Johannes W. Hell, Jessica A. Murphy, Bernardo L. Sabatini, Jessica L. Saulnier, Rui T. Peixoto, Ivar S. Stein, Teresa K. Aman, Naoki Kaneko
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 34, iss 3
The NMDA-type glutamate receptor (NMDAR) is essential for synaptogenesis, synaptic plasticity, and higher cognitive function. Emerging evidence indicates that NMDAR Ca2+permeability is under the control of cAMP/protein kinase A (PKA) signaling. Where
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d99114210c6bd8cb2e8677c6df4d220
https://escholarship.org/uc/item/5d35h2k9
https://escholarship.org/uc/item/5d35h2k9