The Role of NF-κB Triggered Inflammation in Cerebral Ischemia

Autor: Teresa Jover-Mengual, Jee-Yeon Hwang, Hyae-Ran Byun, Brenda L. Court-Vazquez, José M. Centeno, María C. Burguete, R. Suzanne Zukin

Publikováno v: Frontiers in Cellular Neuroscience, Vol 15 (2021)

Cerebral ischemia is a devastating disease that affects many people worldwide every year. The neurodegenerative damage as a consequence of oxygen and energy deprivation, to date, has no known effective treatment. The ischemic insult is followed by an

Externí odkaz: https://doaj.org/article/80b6336ba2af40218f4a0fbf5b4096d9

Gadd45b Acts as Neuroprotective Effector in Global Ischemia-Induced Neuronal Death

Autor: Chang Hoon Cho, Hyae-Ran Byun, Teresa Jover-Mengual, Fabrizio Pontarelli, Christopher Dejesus, Ah-Rhang Cho, R. Suzanne Zukin, Jee-Yeon Hwang

Publikováno v: International Neurourology Journal, Vol 23, Iss Suppl 1, Pp S11-21 (2019)

Purpose Transient global ischemia arising in human due to cardiac arrest causes selective, delayed neuronal death in hippocampal CA1 and cognitive impairment. Growth arrest and DNA-damage-inducible protein 45 beta (Gadd45b) is a wellknown molecule in

Externí odkaz: https://doaj.org/article/4c5bd2ebd2b042a9a0d8f5cb950a9fc9

Gadd45b Acts as Neuroprotective Effector in Global Ischemia-Induced Neuronal Death

Autor: Ah Rhang Cho, Fabrizio Pontarelli, Teresa Jover-Mengual, Christopher Dejesus, Hyae Ran Byun, Jee Yeon Hwang, R. Suzanne Zukin, Chang Hoon Cho

Publikováno v: International Neurourology Journal
International Neurourology Journal, Vol 23, Iss Suppl 1, Pp S11-21 (2019)
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname

Purpose: Transient global ischemia arising in human due to cardiac arrest causes selective, delayed neuronal death in hippocampal CA1 and cognitive impairment. Growth arrest and DNA-damage-inducible protein 45 beta (Gadd45b) is a wellknown molecule i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bb28f53daacd817b69a7952e817df1c
http://europepmc.org/articles/PMC6433207

The selective oestrogen receptor modulator, bazedoxifene, mimics the neuroprotective effect of 17β-oestradiol in diabetic ischaemic stroke by modulating oestrogen receptor expression and the MAPK/ERK1/2 signalling pathway

Autor: María C, Burguete, Teresa, Jover-Mengual, Mikahela A, López-Morales, Alicia, Aliena-Valero, María, Jorques, Germán, Torregrosa, Enrique, Alborch, María, Castelló-Ruiz, Juan B, Salom

Publikováno v: Journal of neuroendocrinologyREFERENCES. 31(8)

Because neuroprotection in stroke should be revisited in the era of recanalisation, the present study analysed the potential neuroprotective effect of the selective oestrogen receptor modulator, bazedoxifene acetate (BZA), in an animal model of diabe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ad73cf6a5f7d1011278bbfa4e3fda4ab
https://pubmed.ncbi.nlm.nih.gov/31127971

Emergent Uric Acid Treatment is Synergistic with Mechanical Recanalization in Improving Stroke Outcomes in Male and Female Rats

Autor: Mikahela A. López-Morales, Ángel Chamorro, David Hervás, Teresa Jover-Mengual, Germán Torregrosa, Alicia Aliena-Valero, María C. Burguete, María Castelló-Ruiz, Juan B. Salom, Enrique C. Leira

Publikováno v: Neuroscience
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname

Preclinical and clinical studies support a promising, albeit not definitive, neuroprotective effect of emergent uric acid (UA) administration in ischemic stroke. We assessed the effects of UA in an ischemic stroke model relevant to the current treatm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b6653c058d359550c253898d47c07a
https://pubmed.ncbi.nlm.nih.gov/30077000