The MDM2-p53 pathway is involved in preconditioning-induced neuronal tolerance to ischemia

Autor: Rebeca Vecino, Maria C. Burguete, Teresa Jover-Mengual, Jesus Agulla, Verónica Bobo-Jiménez, Juan B. Salom, Angeles Almeida, Maria Delgado-Esteban

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)

Abstract Brain preconditioning (PC) refers to a state of transient tolerance against a lethal insult that can be evoked by a prior mild event. It is thought that PC may induce different pathways responsible for neuroprotection, which may involve the

Externí odkaz: https://doaj.org/article/7d5f510a33134e7a88cb679243ce66fa

Impacto de la metodología Flipped Classroom en prácticas de Nutrición y Dietética

Autor: Isabel Torres-Cuevas, Consuelo Burguete, Jose Centeno, Teresa Jover, Lourdes Chuliá

[EN] The educational model has developed new transformations, including the introduction of new pedagogical methodologies such as the Flipped Classroom (FC). FC is a tool that provides greater autonomy for the student, as well as greater assimilation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::882b9dc0be1db8a390c8c4797c897e97
https://hdl.handle.net/10251/190333

Gadd45b Acts as Neuroprotective Effector in Global Ischemia-Induced Neuronal Death

Autor: Ah Rhang Cho, Fabrizio Pontarelli, Teresa Jover-Mengual, Christopher Dejesus, Hyae Ran Byun, Jee Yeon Hwang, R. Suzanne Zukin, Chang Hoon Cho

Publikováno v: International Neurourology Journal
International Neurourology Journal, Vol 23, Iss Suppl 1, Pp S11-21 (2019)
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
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Purpose: Transient global ischemia arising in human due to cardiac arrest causes selective, delayed neuronal death in hippocampal CA1 and cognitive impairment. Growth arrest and DNA-damage-inducible protein 45 beta (Gadd45b) is a wellknown molecule i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bb28f53daacd817b69a7952e817df1c
http://europepmc.org/articles/PMC6433207

The selective oestrogen receptor modulator, bazedoxifene, mimics the neuroprotective effect of 17β-oestradiol in diabetic ischaemic stroke by modulating oestrogen receptor expression and the MAPK/ERK1/2 signalling pathway

Autor: María C, Burguete, Teresa, Jover-Mengual, Mikahela A, López-Morales, Alicia, Aliena-Valero, María, Jorques, Germán, Torregrosa, Enrique, Alborch, María, Castelló-Ruiz, Juan B, Salom

Publikováno v: Journal of neuroendocrinologyREFERENCES. 31(8)

Because neuroprotection in stroke should be revisited in the era of recanalisation, the present study analysed the potential neuroprotective effect of the selective oestrogen receptor modulator, bazedoxifene acetate (BZA), in an animal model of diabe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ad73cf6a5f7d1011278bbfa4e3fda4ab
https://pubmed.ncbi.nlm.nih.gov/31127971

Emergent Uric Acid Treatment is Synergistic with Mechanical Recanalization in Improving Stroke Outcomes in Male and Female Rats

Autor: Mikahela A. López-Morales, Ángel Chamorro, David Hervás, Teresa Jover-Mengual, Germán Torregrosa, Alicia Aliena-Valero, María C. Burguete, María Castelló-Ruiz, Juan B. Salom, Enrique C. Leira

Publikováno v: Neuroscience
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname

Preclinical and clinical studies support a promising, albeit not definitive, neuroprotective effect of emergent uric acid (UA) administration in ischemic stroke. We assessed the effects of UA in an ischemic stroke model relevant to the current treatm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b6653c058d359550c253898d47c07a
https://pubmed.ncbi.nlm.nih.gov/30077000