Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Teresa Greenwell"'
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100908- (2021)
Summary: Oral mucosal tissue is composed of several cell types that are difficult to dissociate while maintaining high cell viability. We describe a protocol for the preparation and dissociation of human buccal and gingival oral mucosal tissue to a h
Externí odkaz:
https://doaj.org/article/086aae39323a4cc8a5788ad84b7bec5b
Autor:
Niki M Moutsopoulos, Natalia I Chalmers, Jennifer J Barb, Loreto Abusleme, Teresa Greenwell-Wild, Nicolas Dutzan, Bruce J Paster, Peter J Munson, Daniel H Fine, Gulbu Uzel, Steven M Holland
Publikováno v:
PLoS Pathogens, Vol 11, Iss 3, p e1004698 (2015)
Leukocyte Adhesion Deficiency I (LAD-I) is a primary immunodeficiency caused by single gene mutations in the CD18 subunit of β2 integrins which result in defective transmigration of neutrophils into the tissues. Affected patients suffer from recurre
Externí odkaz:
https://doaj.org/article/addaa8ab8c734d1885454a19dd2a2995
Autor:
Lakmali M. Silva, Andrew D. Doyle, Teresa Greenwell-Wild, Nicolas Dutzan, Collin L. Tran, Loreto Abusleme, Lih Jiin Juang, Jerry Leung, Elizabeth M. Chun, Andrew G. Lum, Cary S. Agler, Carlos E. Zuazo, Megan Sibree, Priyam Jani, Vardit Kram, Daniel Martin, Kevin Moss, Michail S. Lionakis, Francis J. Castellino, Christian J. Kastrup, Matthew J. Flick, Kimon Divaris, Thomas H. Bugge, Niki M. Moutsopoulos
Publikováno v:
Science. 374
Fibrin gums up the works Plasmin is an abundant plasma protease that cleaves and deactivates the clot-associated protein fibrin. Human deficiencies in plasmin and its inactive proenzyme form, plasminogen (PLG), cause severe inflammation in mucosal ti
Publikováno v:
STAR Protocols
STAR Protocols, Vol 2, Iss 4, Pp 100908-(2021)
STAR Protocols, Vol 2, Iss 4, Pp 100908-(2021)
Summary Oral mucosal tissue is composed of several cell types that are difficult to dissociate while maintaining high cell viability. We describe a protocol for the preparation and dissociation of human buccal and gingival oral mucosal tissue to a hi
Autor:
Heather D. Hickman, Chyi-Chia Richard Lee, Peter Olbrich, Jean K. Lim, Daniel Chauss, Vasileios Oikonomou, Daniel L. Barber, Philip M. Murphy, Monica M. Schmitt, Tilo Freiwald, Marc Swidergall, Stefania Pittaluga, Steven M. Holland, Daniel Martin, Luigi D. Notarangelo, Oliver J. Harrison, Scott G. Filler, Lindsey B. Rosen, Ian A. Myles, Wint Lwin, Sergio M. Pontejo, Behdad Afzali, Timothy J. Break, Niki M. Moutsopoulos, Vincent M. Bruno, Julie Alejo, Jigar V. Desai, Nicolas Bouladoux, Elise M. N. Ferré, Norma V. Solis, Mitsuru Matsumoto, David V. Serreze, Yasmine Belkaid, Andy Renteria, John P. Shannon, Nicolas Dutzan, Teresa Greenwell-Wild, Michail S. Lionakis, Drake W. Williams, Kevin W. Hoffman, Muthulekha Swamydas, Mark S. Anderson
Publikováno v:
Science
Puel and Casanova and Kisand et al . challenge our conclusions that interferonopathy and not IL-17/IL-22 autoantibodies promote candidiasis in autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy. We acknowledge that conclusive evidence
Autor:
Nicolas Dutzan, Andrew P. Sawaya, Teresa Greenwell-Wild, Daniel Martin, Maria I. Morasso, Simone Webb, George Hajishengallis, Niki M. Moutsopoulos, Kimon Divaris, Muzlifah Haniffa, Drake W. Williams, Laurie Brenchley, A. Overmiller
Publikováno v:
Cell
The oral mucosa remains an understudied barrier tissue. This is a site of rich exposure to antigens and commensals, and a tissue susceptible to one of the most prevalent human inflammatory diseases, periodontitis. To aid in understanding tissue-speci
Autor:
Priyam Jani, Teresa Greenwell-Wild, Andrew Gary Lum, Collin Tran, Daniel Martin, Nicolas Dutzan, Kimon Divaris, Andrew D. Doyle, Vardit Kram, Thomas H. Bugge, Cary S. Agler, Francis J. Castellino, Megan M. Sibree, Matthew J. Flick, Lakmali Munasinghage Silva, Niki M. Moutsopoulos
Tissue-specific cues are critical for homeostasis at mucosal barriers. Here, we document that the clotting factor fibrin is a critical regulator of neutrophil function at mucosal barriers. We demonstrate that fibrin engages neutrophils through the α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6af2631d7460a51f7003107e35f84b49
https://doi.org/10.1101/2021.01.15.426743
https://doi.org/10.1101/2021.01.15.426743
Autor:
Julie Alejo, Jigar V. Desai, Ian A. Myles, Niki M. Moutsopoulos, Peter Olbrich, Michail S. Lionakis, Vasileios Oikonomou, Philip M. Murphy, Norma V. Solis, Tilo Freiwald, Scott G. Filler, Heather D. Hickman, Steven M. Holland, Stefania Pittaluga, Sergio M. Pontejo, Teresa Greenwell-Wild, Marc Swidergall, Lindsey B. Rosen, Kevin W. Hoffman, Mark S. Anderson, Timothy J. Break, Vincent M. Bruno, Daniel Chauss, Wint Lwin, Muthulekha Swamydas, Behdad Afzali, Chyi-Chia Richard Lee, David V. Serreze, Daniel Martin, Oliver J. Harrison, Yasmine Belkaid, Jean K. Lim, Andy Renteria, John P. Shannon, Nicolas Dutzan, Monica M. Schmitt, Daniel L. Barber, Luigi D. Notarangelo, Drake W. Williams, Elise M. N. Ferré, Mitsuru Matsumoto, Nicolas Bouladoux
Publikováno v:
Science
Science (New York, N.Y.), vol 371, iss 6526
Science (New York, N.Y.), vol 371, iss 6526
INTRODUCTION: Studies of monogenic diseases have uncovered the importance of immune pathways in human tissue-specific immunity and antimicrobial defense. In particular, human inborn errors of the interleukin-17 (IL-17) receptor signaling pathway and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9858aefc910c2c232d75d169c1c48067
https://hdl.handle.net/11391/1537575
https://hdl.handle.net/11391/1537575
Autor:
Ilias Alevizos, Shyh-Ing Jang, Niki M. Moutsopoulos, Juan Cortes-Troncoso, Paola Perez, Blake M. Warner, Teresa Greenwell-Wild, Tomoko Ikeuchi, Jorge Hidalgo
Publikováno v:
JCI Insight
Sjögren’s syndrome (SS) is a systemic autoimmune disease that mainly affects exocrine salivary and lacrimal glands. Local inflammation in the glands is thought to trigger glandular dysfunction and symptoms of dryness. However, the mechanisms under
Publikováno v:
J Dent Res
Commensal microbiomes exert critical functions at barrier sites. In particular, establishment of the commensal microbiome after birth dictates immune functionality and tissue homeostasis at mucosal surfaces. To investigate the establishment and stabi