Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Teresa Gerhardt"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2022)
Inflammation crucially drives atherosclerosis from disease initiation to the emergence of clinical complications. Targeting pivotal inflammatory pathways without compromising the host defense could compliment therapy with lipid-lowering agents, anti-
Externí odkaz:
https://doaj.org/article/17496053704a484eb86447770dcfb606
Autor:
Dennis Wolf, Nathaly Anto-Michel, Hermann Blankenbach, Ansgar Wiedemann, Konrad Buscher, Jan David Hohmann, Bock Lim, Marina Bäuml, Alex Marki, Maximilian Mauler, Daniel Duerschmied, Zhichao Fan, Holger Winkels, Daniel Sidler, Philipp Diehl, Dirk M Zajonc, Ingo Hilgendorf, Peter Stachon, Timoteo Marchini, Florian Willecke, Maximilian Schell, Björn Sommer, Constantin von zur Muhlen, Jochen Reinöhl, Teresa Gerhardt, Edward F. Plow, Valentin Yakubenko, Peter Libby, Christoph Bode, Klaus Ley, Karlheinz Peter, Andreas Zirlik
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Integrin-based therapeutics could block inflammatory processes but they also impair host defence, limiting their usefulness. Here the authors report an anti-Mac1 antibody that blocks its interaction with pro-inflammatory ligand CD40L but not other li
Externí odkaz:
https://doaj.org/article/ae4c48a947914a8f8492c31615ba0c38
Autor:
Teresa Gerhardt, Barbara E. Stähli, Tanja K. Rudolph, Matthias Lutz, Anne-Sophie Schatz, Lukas Zanders, Tino Schubert, Magnus Stueve, Nick E. J. West, Els Boone, Ulf Landmesser, David M. Leistner
Publikováno v:
Heart and Vessels.
Randomized trials suggest benefits for fractional flow reserve (FFR)-guided vs. angiography-guided treatment strategies in well-defined and selected patient cohorts with acute coronary syndromes (ACS). The long-term prognostic value of FFR measuremen
Publikováno v:
Frontiers in Cardiovascular Medicine
Inflammation crucially drives atherosclerosis from disease initiation to the emergence of clinical complications. Targeting pivotal inflammatory pathways without compromising the host defense could compliment therapy with lipid-lowering agents, anti-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063e8e5e202472c2910d55e4d6a7e0f7
https://refubium.fu-berlin.de/handle/fub188/34490
https://refubium.fu-berlin.de/handle/fub188/34490
Autor:
Xia Sheng, A Lindau, Nicolas Verheyen, C. Bode, I Klymiuk, Dennis Wolf, N Anto Michel, Timoteo Marchini, Teresa Gerhardt, Holger Winkels, W Oswald, T Conhert, Vascular Immunology lab, Sophie Hansen, H Horstmann, Andreas Zirlik
Publikováno v:
European Heart Journal. 42
Aims The distinct function of immune cells in human atherosclerosis has been mostly defined by preclinical mouse studies. Contrastingly, the immune cell composition of human atherosclerotic plaques and their contribution to disease progression is onl
Autor:
Livia Baas, Daniel Sidler, Nathaly Anto Michel, Sophie Hansen, Maximilian Schell, Holger Winkels, Peter Stachon, Kouji Kobiyama, Konrad Buscher, Catherine C. Hedrick, Takayuki Kimura, Andreas Zirlik, Ingo Hilgendorf, Jacqueline Miller, Sara McArdle, Klaus Ley, Amal J. Ali, Lucia Sol Mitre, Melanie Vassallo, Teresa Gerhardt, Xia Sheng, Hauke Horstmann, Dennis Wolf, Thamotharampillai Dileepan, Akula Bala Pramod, Dalia E. Gaddis, Simon Brunel, Zbigniew Mikulski, Yanal Ghosheh, Erik Ehinger, Bjoern Peters, Alessandro Sette, Chris A. Benedict
Publikováno v:
Circulation
Supplemental Digital Content is available in the text.
Background: Throughout the inflammatory response that accompanies atherosclerosis, autoreactive CD4+ T-helper cells accumulate in the atherosclerotic plaque. Apolipoprotein B100 (apoB), the
Background: Throughout the inflammatory response that accompanies atherosclerosis, autoreactive CD4+ T-helper cells accumulate in the atherosclerotic plaque. Apolipoprotein B100 (apoB), the
Autor:
Karlheinz Peter, Valentin P. Yakubenko, Bock Lim, Philipp Diehl, Alex Marki, Klaus Ley, Björn Sommer, Jochen Reinöhl, Jan David Hohmann, Constantin von zur Mühlen, Maximilian Mauler, Peter Stachon, Ansgar Wiedemann, Holger Winkels, Daniel Duerschmied, Peter Libby, Dirk M. Zajonc, Andreas Zirlik, Daniel Sidler, Florian Willecke, Zhichao Fan, Maximilian Schell, Marina Bäuml, Nathaly Anto-Michel, Ingo Hilgendorf, Christoph Bode, Teresa Gerhardt, Dennis Wolf, Timoteo Marchini, Konrad Buscher, Hermann Blankenbach, Edward F. Plow
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Nature Communications
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Integrin-based therapeutics have garnered considerable interest in the medical treatment of inflammation. Integrins mediate the fast recruitment of monocytes and neutrophils to the site of inflammation, but are also required for host defense, limitin
Autor:
Kevin Tse, Klaus Ley, Takayuki Kimura, Zbigniew Mikulski, Sara McArdle, Dennis Wolf, Jacqueline Miller, Alessandro Sette, John Sidney, Teresa Gerhardt
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 312:H781-H790
Although immunization with major histocompatibility complex (MHC) class II-restricted apolipoprotein B (ApoB) peptides has been shown to be atheroprotective, the mechanism is unclear. Here, we investigated CD4+ T cell populations in immunized atheros
Autor:
Dennis Wolf, Teresa Gerhardt, Nathaly Anto Michel, Bjarke Hansen, Alessandro Sette, Andreas Zirlik, Marc K Jenkins, Klaus Ley
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37
Background: In atherosclerosis, CD4 + T helper cells recognize auto-antigens including ApoB, the main protein in low-density lipoprotein (LDL). However, atherosclerosis-specific, auto-reactive CD4 + T cells have not been detected in vivo , and their
Publikováno v:
Cardiac and Vascular Biology ISBN: 9783319662237
Atherosclerosis and attendant cardiovascular disease account for most deaths worldwide. Despite considerable progress in understanding disease mechanisms, the only causal treatment strategy is lowering LDL cholesterol. Atherosclerosis is a complex di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd6fb9f8982c254d1b552270b611a4a9
https://doi.org/10.1007/978-3-319-66224-4_3
https://doi.org/10.1007/978-3-319-66224-4_3