Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Teresa Gómez-Isla"'
Autor:
Raquel N. Taddei, Maria V. Sanchez-Mico, Orla Bonnar, Theresa Connors, Angelica Gaona, Dominique Denbow, Matthew P. Frosch, Teresa Gómez-Isla
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-20 (2022)
Abstract Clinico-pathological correlation studies show that some otherwise healthy elderly individuals who never developed cognitive impairment harbor a burden of Alzheimer’s disease lesions (plaques and tangles) that would be expected to result in
Externí odkaz:
https://doaj.org/article/1238c6cf62e84423870a4194a09ab6e9
Autor:
Marta Marquié, Cinthya Agüero, Ana C. Amaral, Alberto Villarejo-Galende, Prianca Ramanan, Michael Siao Tick Chong, Nil Sáez-Calveras, Rachel E. Bennett, Eline E. Verwer, Sally Ji Who Kim, Maeva Dhaynaut, Victor E. Alvarez, Keith A. Johnson, Ann C. McKee, Matthew P. Frosch, Teresa Gómez-Isla
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-12 (2019)
Abstract Introduction Chronic traumatic encephalopathy (CTE) is a tauopathy associated to repetitive head trauma. There are no validated in vivo biomarkers of CTE and a definite diagnosis can only be made at autopsy. Recent studies have shown that po
Externí odkaz:
https://doaj.org/article/9039b5f7fb4e47e382c4f828adc7d929
Autor:
Marta Marquié, Eline E. Verwer, Avery C. Meltzer, Sally Ji Who Kim, Cinthya Agüero, Jose Gonzalez, Sara J. Makaretz, Michael Siao Tick Chong, Prianca Ramanan, Ana C. Amaral, Marc D. Normandin, Charles R. Vanderburg, Stephen N. Gomperts, Keith A. Johnson, Matthew P. Frosch, Teresa Gómez-Isla
Publikováno v:
Acta Neuropathologica Communications, Vol 5, Iss 1, Pp 1-13 (2017)
Abstract [F-18]-AV-1451 is a novel positron emission tomography (PET) tracer with high affinity to neurofibrillary tau pathology in Alzheimer’s disease (AD). PET studies have shown increased tracer retention in patients clinically diagnosed with de
Externí odkaz:
https://doaj.org/article/34773be917864314bff60df6ef23259c
Autor:
Elena M. Ribé, Mar Pérez, Berta Puig, Ignasi Gich, Filip Lim, Mar Cuadrado, Teresa Sesma, Silvia Catena, Belén Sánchez, María Nieto, Pilar Gómez-Ramos, M.Asunción Morán, Felipe Cabodevilla, Lluis Samaranch, Lourdes Ortiz, Alberto Pérez, Isidro Ferrer, Jesús Avila, Teresa Gómez-Isla
Publikováno v:
Neurobiology of Disease, Vol 20, Iss 3, Pp 814-822 (2005)
Even though the idea that amyloid β peptide accumulation is the primary event in the pathogenesis of Alzheimer's disease has become the leading hypothesis, the causal link between aberrant amyloid precursor protein processing and tau alterations in
Externí odkaz:
https://doaj.org/article/a17b503872814265a8414ea2c3cf1612
Autor:
Olga Calero, María J Bullido, Jordi Clarimón, Ana Frank-García, Pablo Martínez-Martín, Alberto Lleó, María Jesús Rey, Alberto Rábano, Rafael Blesa, Teresa Gómez-Isla, Fernando Valdivieso, Jesús de Pedro-Cuesta, Isidro Ferrer, Miguel Calero
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22090 (2011)
Alzheimer's disease (AD) and Creutzfeldt-Jakob disease (CJD) represent two distinct clinical entities belonging to a wider group, generically named as conformational disorders that share common pathophysiologic mechanisms. It is well-established that
Externí odkaz:
https://doaj.org/article/9b7eb87b30b643018ebed046b1d22717
Autor:
Teresa Gómez-Isla, Matthew P. Frosch
Publikováno v:
Nature Reviews Neurology. 18:323-332
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc37c614e62c3eb8e643ab6509259591
https://doi.org/10.1038/s41582-022-00642-9
https://doi.org/10.1038/s41582-022-00642-9
Autor:
Sebastián Cervantes, Pablo Martinez-Lage, Teresa Gómez-Isla, Jose Antonio Cabranes, A. Lleo, Ana Barabash, Rafael Blesa, Jordi Clarimón, Alberto Marcos, Isabel Lamet, Alvaro Alonso, Daniel Alcolea, Elena Lorenzo, Pau Pastor, Lluis Samaranch, Inés Ancín
Publikováno v:
Journal of Alzheimer's Disease. 22:1065-1071
Microtubule-associated protein tau (MAPT) and apolipoprotein E (APOE) are involved in the pathogenic mechanisms of Alzheimer's disease (AD). We prospectively followed three longitudinal independent samples (total n=319) with amnestic mild cognitive i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74fe444baac763b6d84fd16f730e2e6d
https://doi.org/10.3233/jad-2010-101011
https://doi.org/10.3233/jad-2010-101011
Autor:
Alberto Lleó, Albert Lladó, Jordi Clarimón, Raquel Sánchez-Valle, Marta Pera, Isidre Ferrer, Rafael Blesa, Cristina Guardia-Laguarta, Teresa Gómez-Isla, Mireia Coma, José Luis Molinuevo
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 69:53-59
We report the clinical, pathologic, and biochemical characteristics of the recently described amyloid precursor protein (APP) I716F mutation. We present the clinical findings of individuals carrying the APP I716F mutation and the neuropathologic exam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2339aebecd0ce28c0eb235f3d41ceb3
https://doi.org/10.1097/nen.0b013e3181c6b84d
https://doi.org/10.1097/nen.0b013e3181c6b84d
Autor:
Teresa Gómez-Isla, Jordi Clarimón, Coro Paisán-Ruiz, AB Singleton, Alberto Lleó, John Hardy, Rita Guerreiro, José Luis Molinuevo, Ruth Djaldetti, Rafael Blesa
Publikováno v:
Neurobiol Aging
Early-onset Alzheimer’s disease (EOAD) is a clinically and genetically heterogeneous condition in which the typical features appear significantly earlier in life (before 65 years). Mutations in three genes (PSEN1, PSEN2, and APP) have been identifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d824e7568aa324de21e46494a786d00
https://doi.org/10.1016/j.neurobiolaging.2008.02.008
https://doi.org/10.1016/j.neurobiolaging.2008.02.008
Autor:
Pia Kivisäkk, Becky C. Carlyle, Thadryan Sweeney, Bianca A. Trombetta, Kathryn LaCasse, Leena El-Mufti, Idil Tuncali, Lori B. Chibnik, Sudeshna Das, Clemens R. Scherzer, Keith A. Johnson, Bradford C. Dickerson, Teresa Gomez-Isla, Deborah Blacker, Derek H. Oakley, Matthew P. Frosch, Bradley T. Hyman, Anahit Aghvanyan, Pradeepthi Bathala, Christopher Campbell, George Sigal, Martin Stengelin, Steven E. Arnold
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundThe last few years have seen major advances in blood biomarkers for Alzheimer's Disease (AD) with the development of ultrasensitive immunoassays, promising to transform how we diagnose, prognose, and track progression of neurodegenerative d
Externí odkaz:
https://doaj.org/article/6404f04c0c8f4fdea79ffcc9b0fb11c5