Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Teresa G, Granda"'
Autor:
Elisabeth Filipski, Rune Smaaland, Paolo Sassone-Corsi, Teresa G. Granda, Nicolas Cermakian, Francis Lévi, Xu-Hui Liu
Publikováno v:
FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2005, 19 (2), pp.304-6. ⟨10.1096/fj.04-2665fje⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2005, 19 (2), pp.304-6. ⟨10.1096/fj.04-2665fje⟩
International audience; Proapoptotic drugs such as docetaxel displayed least toxicity and highest antitumor efficacy following dosing during the circadian rest phase in mice, suggesting that cell cycle and apoptotic processes could be regulated by th
Publikováno v:
Pathologie Biologie. 51:212-215
To study time-scheduled regimens in the treatment of tumours by cytotoxic drugs delivered by IV injection, we propose a mathematical model of the action of a chemotherapy on the population of tumoral cells on the one hand, on a population of fast ren
Autor:
Bruno Claustrat, Marie-Christine Mormont, Xiao-Mei Li, Francis Lévi, Michael H. Hastings, Teresa G. Granda, Elisabeth Filipski, Verdun M. King
Publikováno v:
Pathologie Biologie. 51:216-219
An animal model (mice B6D2F1) was developed to study the consequence of suprachiasmatic nuclei (SCN) destruction on tumor growth. SCN destruction abolished the rest-activity and body temperature rhythms and markedly altered the rhythms in serum corti
Autor:
Verdun M. King, Francis Lévi, Marie-Christine Mormont, Xu-Hui Liu, Teresa G. Granda, Elisabeth Filipski, Bruno Claustrat, Xiao-Mei Li, Michael H. Hastings
Publikováno v:
CancerSpectrum Knowledge Environment. 94:690-697
Background: The circadian timing system controlled by the suprachiasmatic nuclei (SCN) of the hypothalamus regulates daily rhythms of motor activity and adrenocortical secretion. An alteration in these rhythms is associated with poor survival of pati
Autor:
Elisabeth Filipski, R M D'Attino, Vrignaud P, Francis Lévi, E. Terzoli, Bissery Mc, Teresa G. Granda, Carlo Garufi
Publikováno v:
British Journal of Cancer
The relevance of circadian rhythms in irinotecan and oxaliplatin tolerability was investigated with regard to antitumour activity. Mice bearing Glasgow osteosarcoma (GOS) received single agent irinotecan (50 or 60 mg kg−1 per day) or oxaliplatin (4
Autor:
Idoia Ortega-Martínez, María Dolores Boyano, Bruno Blaya, Teresa G Granda, Erika Alonso Tejerina
Publikováno v:
Journal of Clinical & Experimental Dermatology Research.
Multiferon® (HuIFN-alpha-Le) (MF) is a natural interferon alpha used in several countries for the treatment of selected viral infections and as an adjuvant treatment in different types of cancer, including melanoma. We have examined the influence of
Autor:
Paolo Pevarello, Milagros Lorenzo, Teresa G. Granda, David Soilan, Sandra Peregrina, María Isabel Albarrán, Obdulia Rabal, Amancio Carnero, Beatriz G. Serelde, Patricia Alfonso, Antonio Cebriá, Plácido A. Ceballos, Julen Oyarzabal, Jesús Fominaya, Ana-Isabel Hernández, James R. Bischoff, Wolfgang Link, Guido Kurz, Oliver Renner
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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9 páginas, 4 figuras, 1 tabla.
Activation of the phosphoinositide 3-kinase (PI3K)/Akt signaling pathway is one the most frequent genetic events in human cancer. A cell-based imaging assay that monitored the translocation of the Akt effector pro
Activation of the phosphoinositide 3-kinase (PI3K)/Akt signaling pathway is one the most frequent genetic events in human cancer. A cell-based imaging assay that monitored the translocation of the Akt effector pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0dc98bcd67fa063d8869121bed1dd17
http://hdl.handle.net/10261/38823
http://hdl.handle.net/10261/38823
Autor:
Xiao-Mei Li, Elisabeth Filipski, Marie-Christine Etienne, Bruno Claustrat, Gérard Milano, Teresa G. Granda, Michael H. Hastings, Francis Lévi, Verdun M. King
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 287(4)
Rest-activity or cortisol rhythms can be altered in cancer patients, a condition that may impair the benefits from a timed delivery of anticancer treatments. In rodents, the circadian pattern in rest-activity is suppressed by the destruction of the s
Publikováno v:
Pathologie-biologie. 51(4)
We previously demonstrated a circadian rhythm in response to docetaxel chemotherapy in C3H/HeN mice bearing MA13/C mammary adenocarcinoma. We investigated the relation between this rhythm and the expression of BCL-2 in bone marrow and in tumor tissue
Autor:
Teresa G. Granda, Francis Lévi
Publikováno v:
Chronobiology international. 19(1)
Experimental tumor models constitute a prerequisite toward chronotherapy testing in cancer patients. Studies in experimental models are required to understand the relation between tumor rhythms and antitumor treatments efficacy. In healthy tissues, c