Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Teresa Eichenlaub"'
Autor:
Casper Groth, Pooja Vaid, Aditi Khatpe, Nelchi Prashali, Avantika Ahiya, Diana Andrejeva, Madhumita Chakladar, Sanket Nagarkar, Rachel Paul, Devaki Kelkar, Teresa Eichenlaub, Hector Herranz, TS Sridhar, Stephen M. Cohen, LS Shashidhara
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 9, Pp 2999-3008 (2020)
Genetic approaches in Drosophila have successfully identified many genes involved in regulation of growth control as well as genetic interactions relevant to the initiation and progression of cancer in vivo. Here, we report on large-scale RNAi-based
Externí odkaz:
https://doaj.org/article/e1fb7176b05c46169a5d8e011d094d80
Publikováno v:
Cell Reports, Vol 23, Iss 5, Pp 1491-1503 (2018)
Summary: Cytokinesis failure may result in the formation of polyploid cells, and subsequent mitosis can lead to aneuploidy and tumor formation. Tumor suppressor mechanisms limiting the oncogenic potential of these cells have been described. However,
Externí odkaz:
https://doaj.org/article/d6f7c94b15ff4e1594830401f7d23523
Autor:
T.S. Sridhar, Rachel Paul, Devaki A. Kelkar, Aditi Khatpe, Pooja M. Vaid, Avantika Ahiya, Casper Groth, Teresa Eichenlaub, Sanket Nagarkar, Nelchi Prashali, Madhumita Chakladar, Héctor Herranz, Diana Andrejeva, Stephen M. Cohen, L. S. Shashidhara
Publikováno v:
G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 10, Iss 9, Pp 2999-3008 (2020)
Groth, C, Vaid, P, Khatpe, A, Prashali, N, Ahiya, A, Andrejeva, D, Chakladar, M, Nagarkar, S, Paul, R, Kelkar, D, Eichenlaub, T, Herranz, H, Sridhar, T S, Cohen, S M & Shashidhara, L S 2020, ' Genome-wide screen for context-dependent tumor suppressors identified using in vivo models for neoplasia in Drosophila ', G3: Genes, Genomes, Genetics, vol. 10, no. 9, pp. 2999-3008 . https://doi.org/10.1534/g3.120.401545
G3: Genes, Genomes, Genetics, Vol 10, Iss 9, Pp 2999-3008 (2020)
Groth, C, Vaid, P, Khatpe, A, Prashali, N, Ahiya, A, Andrejeva, D, Chakladar, M, Nagarkar, S, Paul, R, Kelkar, D, Eichenlaub, T, Herranz, H, Sridhar, T S, Cohen, S M & Shashidhara, L S 2020, ' Genome-wide screen for context-dependent tumor suppressors identified using in vivo models for neoplasia in Drosophila ', G3: Genes, Genomes, Genetics, vol. 10, no. 9, pp. 2999-3008 . https://doi.org/10.1534/g3.120.401545
Genetic approaches in Drosophila have successfully identified many genes involved in regulation of growth control as well as genetic interactions relevant to the initiation and progression of cancer in vivo. Here, we report on large-scale RNAi-based
Autor:
Teresa Eichenlaub, Stephen M. Cohen, Diana Andrejeva, Casper Groth, L. S. Shashidhara, Rachel Paul, Madhumita Chakladar, Sanket Nagarkar, TS Sridhar, Aditi Khatpe, Héctor Herranz, Pooja M. Vaid, Avantika Ahiya, Nelchi Prashali
Genetic approaches in Drosophila have successfully identified many genes involved in regulation of growth control as well as genetic interactions relevant to the initiation and progression of cancer in vivo. Here, we report on large-scale RNAi-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2674314ad9cc2f994946960af2f3212
https://doi.org/10.1101/643221
https://doi.org/10.1101/643221
Publikováno v:
Current Biology. 26:419-427
Cell competition is a homeostatic process in which proliferating cells compete for survival. Elimination of otherwise normal healthy cells through competition is important during development and has recently been shown to contribute to maintaining ti
Publikováno v:
Development.
Tissue growth has to be carefully controlled to generate well-functioning organs. MicroRNAs are small non-coding RNAs that modulate the activity of target genes and play a pivotal role in animal development. Understanding the functions of microRNAs i
Autor:
Blanca I. Aldana, Stephen M. Cohen, Jan Gorodkin, Flávia Cristina de Paula Freitas, Ole W. Petersen, Teresa Eichenlaub, Diana Andrejeva, Hung Than Nguyen, Héctor Herranz, René Villadsen
Publikováno v:
Eichenlaub, T, Villadsen, R, Freitas, F C P, Andrejeva, D, Aldana, B I, Nguyen, H T, Petersen, O W, Gorodkin, J, Herranz, H & Cohen, S M 2018, ' Warburg Effect Metabolism Drives Neoplasia in a Drosophila Genetic Model of Epithelial Cancer ', Current Biology, vol. 28, no. 20, pp. 3220-3228.e6 . https://doi.org/10.1016/j.cub.2018.08.035
Cancers develop in a complex mutational landscape. Genetic models of tumor formation have been used to explore how combinations of mutations cooperate to promote tumor formation in vivo. Here, we identify lactate dehydrogenase (LDH), a key enzyme in
Publikováno v:
Development (Cambridge, England). 145(13)
Tissue growth has to be carefully controlled to generate well-functioning organs. MicroRNAs are small non-coding RNAs that modulate the activity of target genes and play a pivotal role in animal development. Understanding the functions of microRNAs i
Publikováno v:
Current topics in developmental biology. 116
Cancer genomics has greatly increased our understanding of the complexity of the genetic and epigenetic changes found in human tumors. Understanding the functional relationships among these elements calls for the use of flexible genetic models. We di
Cancer genomics has greatly increased our understanding of the complexity of the genetic and epigenetic changes found in human tumors. Understanding the functional relationships among these elements calls for the use of flexible genetic models. We di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d7a3de2616321f2c687ca30ddea02ca
https://doi.org/10.1016/bs.ctdb.2015.11.037
https://doi.org/10.1016/bs.ctdb.2015.11.037