Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Teresa Canedo"'
Autor:
Renato Socodato, Artur Rodrigues-Santos, Joana Tedim-Moreira, Tiago O. Almeida, Teresa Canedo, Camila C. Portugal, João B. Relvas
Publikováno v:
Cell Death and Disease, Vol 14, Iss 10, Pp 1-15 (2023)
Abstract Microglia are the largest myeloid cell population in the brain. During injury, disease, or inflammation, microglia adopt different functional states primarily involved in restoring brain homeostasis. However, sustained or exacerbated microgl
Externí odkaz:
https://doaj.org/article/3994b4d2fd7c4a6cbc6d01adeccdeaee
Autor:
Renato Socodato, Tiago O. Almeida, Camila C. Portugal, Evelyn C.S. Santos, Joana Tedim-Moreira, João Galvão-Ferreira, Teresa Canedo, Filipa I. Baptista, Ana Magalhães, António F. Ambrósio, Cord Brakebusch, Boris Rubinstein, Irina S. Moreira, Teresa Summavielle, Inês Mendes Pinto, João B. Relvas
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113447- (2023)
Summary: Microglia, the largest population of brain immune cells, continuously interact with synapses to maintain brain homeostasis. In this study, we use conditional cell-specific gene targeting in mice with multi-omics approaches and demonstrate th
Externí odkaz:
https://doaj.org/article/914f35ba494042d8aa265dd02cbdf0a4
Autor:
Renato Socodato, Artur Rodrigues-Santos, Joana Tedim-Moreira, Tiago O. Almeida, Teresa Canedo, Camila C. Portugal, João B. Relvas
Publikováno v:
Cell Death and Disease, Vol 14, Iss 12, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/cd49438762284808bc57043927df0d87
Autor:
Joana Bravo, Inês Ribeiro, Ana Filipa Terceiro, Elva B. Andrade, Camila Cabral Portugal, Igor M. Lopes, Maria M. Azevedo, Mafalda Sousa, Cátia D. F. Lopes, Andrea C. Lobo, Teresa Canedo, João Bettencourt Relvas, Teresa Summavielle
Publikováno v:
Cells, Vol 11, Iss 3, p 355 (2022)
Exposure to methamphetamine (Meth) has been classically associated with damage to neuronal terminals. However, it is now becoming clear that addiction may also result from the interplay between glial cells and neurons. Recently, we demonstrated that
Externí odkaz:
https://doaj.org/article/99f8fd3a7e914b0795b99e0aaca80aec
Autor:
Camila C. Portugal, Nuno Sousa, Ana Filipa Terceiro, João Duarte Magalhães, João B. Relvas, Teresa Summavielle, Tiago Almeida, Joana Bravo, Renato Socodato, Teresa Canedo, Ana Isabel Silva, João Filipe Oliveira, Ana Magalhães, Sónia Guerra-Gomes
Publikováno v:
Neuropsychopharmacology
Methamphetamine (Meth) is a powerful illicit psychostimulant, widely used for recreational purposes. Besides disrupting the monoaminergic system and promoting oxidative brain damage, Meth also causes neuroinflammation, contributing to synaptic dysfun
Autor:
I Pinto, Teresa Canedo, Filipa I. Baptista, Ana Magalhães, Boris Rubinstein, Camila C. Portugal, João B. Relvas, Teresa Summavielle, Tiago Almeida, Irina S. Moreira, Cord Brakebusch, Renato Socodato, António F. Ambrósio, Evelyn C. S. Santos, Joana Tedim-Moreira
Microglial homeostatic functions are fundamental to regulate the central nervous system microenvironment. We use conditional cell-specific gene targeting, RNA-seq profiling, high-throughput proteomics, phosphoproteomics, systems biology, and animal b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00e3831446a29b0cf936b59361b8b5a9
https://doi.org/10.1101/2021.10.18.464802
https://doi.org/10.1101/2021.10.18.464802
Autor:
Ana Magalhães, Tiago Almeida, João Filipe Oliveira, Teresa Canedo, João B. Relvas, Camila C. Portugal, João Duarte Magalhães, Renato Socodato, Sónia Guerra-Gomes, Joana Bravo, Nuno Sousa, Teresa Summavielle
Methamphetamine (Meth) is a powerful illicit psychostimulant, widely used for recreational purposes. Besides disrupting the monoaminergic system and promoting oxidative brain damage, Meth also causes neuroinflammation that contributes to synaptic dys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c04b2b0623c0981139853c1eb9e52cdb
https://doi.org/10.1101/2021.02.22.432170
https://doi.org/10.1101/2021.02.22.432170
Autor:
Joana F. Henriques, Renata L. Alves, Ana Magalhães, Teresa Summavielle, Teresa Canedo, Camila C. Portugal, Cátia M. Silva, João B. Relvas, Renato Socodato, Tiago Almeida, Joana Tedim-Moreira
Alcohol abuse adversely affects the lives of millions of people worldwide. Deficits in synaptic transmission and in microglial function are commonly found in human alcohol abusers and in animal models of alcohol intoxication. Here, we found that a pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5323d1d38dd85484e38fe3dc3daa066
https://hdl.handle.net/10216/140511
https://hdl.handle.net/10216/140511
Autor:
Ana Magalhães, Teresa Canedo, Renata L. Alves, Ana M. F. P. Silva, Sandra H. Vaz, Tiago Almeida, Renato Socodato, Cátia M. Silva, Ana M. Sebastião, João B. Relvas, António F. Ambrósio, Cord Brakebusch, Joana F. Henriques, Roberto Paes-de-Carvalho, Teresa Summavielle, Filipa I. Baptista, João P. Magalhães, Artur Rodrigues, Camila C. Portugal, Vanessa Coelho-Santos
Publikováno v:
Socodato, R, Portugal, C C, Canedo, T, Rodrigues, A, Almeida, T O, Henriques, J F, Vaz, S H, Magalhães, J, Silva, C M, Baptista, F I, Alves, R L, Coelho-Santos, V, Silva, A P, Paes-de-Carvalho, R, Magalhães, A, Brakebusch, C, Sebastião, A M, Summavielle, T, Ambrósio, A F & Relvas, J B 2020, ' Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration ', Cell Reports, vol. 31, no. 12, 107796, pp. 1-29 . https://doi.org/10.1016/j.celrep.2020.107796
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Cell Reports
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Cell Reports
© 2020 The Author(s). Creative Commons Attribution (CC BY 4.0)
Nervous tissue homeostasis requires the regulation of microglia activity. Using conditional gene targeting in mice, we demonstrate that genetic ablation of the small GTPase Rhoa in
Nervous tissue homeostasis requires the regulation of microglia activity. Using conditional gene targeting in mice, we demonstrate that genetic ablation of the small GTPase Rhoa in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb571fceba1952acaecbe0bcbe6bc791
https://curis.ku.dk/portal/da/publications/microglia-dysfunction-caused-by-the-loss-of-rhoa-disrupts-neuronal-physiology-and-leads-to-neurodegeneration(af46c589-efa7-462d-8150-2a9c7d52e48a).html
https://curis.ku.dk/portal/da/publications/microglia-dysfunction-caused-by-the-loss-of-rhoa-disrupts-neuronal-physiology-and-leads-to-neurodegeneration(af46c589-efa7-462d-8150-2a9c7d52e48a).html
Autor:
Renato Socodato, Teresa Summavielle, Joana Tedim-Moreira, Renata L. Alves, Cátia M. Silva, João B. Relvas, Tiago Almeida, Teresa Canedo, Camila C. Portugal, Ana Magalhães, Joana F. Henriques
Alcohol use adversely impacts the life of millions of people worldwide. Deficits in synaptic transmission and in microglial function are common findings in human alcohol users and in animal models of alcohol intoxication. Here, we show that alcohol i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::536b583126b47cbd32b71611f0fc683d
https://doi.org/10.1101/870279
https://doi.org/10.1101/870279