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Autor:
Shaun W. Lee, Teresa Brito-Robionson, Cunjia Qiu, Zhong Liang, Victoria A. Ploplis, Rashna D. Balsara, Jaroslav Zajicek, Yue Yuan, Francis J. Castellino
Publikováno v:
Journal of Structural Biology. 204:151-164
Group A Streptococcus pyogenes (GAS) is a causative agent of pharyngeal and dermal infections in humans. A major virulence determinant of GAS is its dimeric signature fibrillar M-protein (M-Prt), which is evolutionarily designed in modules, ranging f