Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Teresa A. Cassel"'
Autor:
Rony Panarsky, Daniel R. Crooks, Andrew N. Lane, Youfeng Yang, Teresa A. Cassel, Teresa W.-M. Fan, W. Marston Linehan, Jeffrey A. Moscow
Publikováno v:
Cancer & Metabolism, Vol 8, Iss 1, Pp 1-15 (2020)
Abstract Background The loss-of-function mutation of fumarate hydratase (FH) is a driver of hereditary leiomyomatosis and renal cell carcinoma (HLRCC). Fumarate accumulation results in activation of stress-related mechanisms leading to upregulation o
Externí odkaz:
https://doaj.org/article/0dceb078fdad4b62bc2e715b95444bdb
Autor:
Timothy L. Scott, Juan Zhu, Teresa A. Cassel, Sara Vicente-Muñoz, Penghui Lin, Richard M. Higashi, Andrew N. Lane, Teresa W.-M. Fan
Publikováno v:
Metabolites, Vol 12, Iss 8, p 760 (2022)
Glycogen is a readily deployed intracellular energy storage macromolecule composed of branched chains of glucose anchored to the protein glycogenin. Although glycogen primarily occurs in the liver and muscle, it is found in most tissues, and its meta
Externí odkaz:
https://doaj.org/article/130af625bf0240b28d4779f4a79268fe
Autor:
Teresa W.-M. Fan, Saeed Daneshmandi, Teresa A. Cassel, Mohammad B. Uddin, James Sledziona, Patrick T. Thompson, Penghui Lin, Richard M. Higashi, Andrew N. Lane
Publikováno v:
The Journal of Immunology. 209:1674-1690
Immunomodulatory (IM) metabolic reprogramming in macrophages (Mϕs) is fundamental to immune function. However, limited information is available for human Mϕs, particularly in response plasticity, which is critical to understanding the variable effi
Autor:
JN Rashida Gnanaprakasam, Lingling Liu, Xuyong Chen, Siwen Kang, Tingting Wang, Teresa A. Cassel, Christopher M. Adams, Richard M Higashi, David A. Scott, Gang Xin, Jun Yang, Andrew N. Lane, Teresa W.-M. Fan, Ji Zhang, Ruoning Wang
Robust and effective T cell immune surveillance and cancer immunotherapy require properly allocating metabolic resources to sustain energetically costly processes, including growth and cytokine production. Amino acids are major cellular constituents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cd3813e670b87088d397923ce0cc13c
https://doi.org/10.1101/2022.07.18.500458
https://doi.org/10.1101/2022.07.18.500458
Autor:
Teresa W. M. Fan, Saeed Daneshmandi, Teresa A. Cassel, Mohammad B. Uddin, James Sledziona, Patrick T. Thompson, Penghui Lin, Richard M. Higashi, Andrew N. Lane
Publikováno v:
Cancer Research. 82:2537-2537
We combined multiplex Stable Isotope-Resolved Metabolomics (mSIRM) with Reverse Phase Protein Array (RPPA) to map the time course changes of IM metabolic network and key protein regulators in four human donors’ MΦ’s in response to differential p
Autor:
Andrew N. Lane, Timothy L. Scott, Juan Zhu, Teresa A. Cassel, Sara Vicente-Munoz, Penghui Lin, Richard M. Higashi, Teresa W-M Fan
Publikováno v:
Cancer Research. 82:2324-2324
Introduction: Glycogen is a readily deployed intracellular energy storage macromolecule composed of branched chains of glucose. Although glycogen primarily occurs in the liver and muscle, it can be found in most tissues throughout the body, and its m
Autor:
Gaojian Lian, JN Rashida Gnanaprakasam, Tingting Wang, Ruohan Wu, Xuyong Chen, Lingling Liu, Yuqing Shen, Mao Yang, Jun Yang, Ying Chen, Vasilis Vasiliou, Teresa A Cassel, Douglas R Green, Yusen Liu, Teresa WM Fan, Ruoning Wang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dab11644ce1400a4b5608e0ebfb3027b
https://doi.org/10.7554/elife.36158.029
https://doi.org/10.7554/elife.36158.029
Autor:
Gaojian Lian, JN Rashida Gnanaprakasam, Tingting Wang, Ruohan Wu, Xuyong Chen, Lingling Liu, Yuqing Shen, Mao Yang, Jun Yang, Ying Chen, Vasilis Vasiliou, Teresa A Cassel, Douglas R Green, Yusen Liu, Teresa WM Fan, Ruoning Wang
Publikováno v:
eLife, Vol 7 (2018)
Upon antigen stimulation, T lymphocytes undergo dramatic changes in metabolism to fulfill the bioenergetic, biosynthetic and redox demands of proliferation and differentiation. Glutathione (GSH) plays an essential role in controlling redox balance an
Externí odkaz:
https://doaj.org/article/e8819e6fdf194278bb450949aa945620