Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Teresa, Michalkiewicz"'
Publikováno v:
Physiological Reports, Vol 8, Iss 18, Pp n/a-n/a (2020)
Abstract We investigated the hypothesis that exposure of lungs at the saccular stage of development to hyperoxia leads to persistent growth arrest and dysfunction of 5’AMP‐activated protein kinase (AMPK), a key energy sensor in the cell. We expos
Externí odkaz:
https://doaj.org/article/d30ced049973427c83866079895be877
Autor:
Devashis, Mukherjee, Ujala, Rana, Alison J, Kriegel, Pengyuan, Liu, Teresa, Michalkiewicz, Girija Ganesh, Konduri
Publikováno v:
Pediatric Research. 93:551-558
Persistent pulmonary hypertension of the newborn (PPHN) occurs when pulmonary vascular resistance (PVR) fails to decrease at birth. Decreased angiogenesis in the lung contributes to the persistence of high PVR at birth. MicroRNAs (miRNAs) regulate ge
Autor:
Ru-Jeng Teng, Girija G. Konduri, Ujala Rana, Adeleye J. Afolayan, Abdul K. Parchur, Megha Sharma, Chintamani Joshi, Amit Joshi, Teresa Michalkiewicz
Publikováno v:
Am J Respir Cell Mol Biol
Impaired angiogenesis function in pulmonary artery endothelial cells (PAEC) contributes to persistent pulmonary hypertension of the newborn (PPHN). Decreased nitric oxide (NO) amounts in PPHN lead to impaired mitochondrial biogenesis and angiogenesis
Autor:
Abdul K. Parchur, Brianna Entringer, Teresa Michalkiewicz, Girija G. Konduri, Ru-Jeng Teng, Amit Joshi, Ujala Rana, Emily Callan
Publikováno v:
Am J Respir Cell Mol Biol
Decreased angiogenesis contributes to persistent pulmonary hypertension of the newborn (PPHN); mechanisms remain unclear. AMPK (5′AMP activated protein kinase) is a key regulator of cell metabolism. We investigated the hypothesis that a decrease in
Autor:
Amber Majnik, Teresa Michalkiewicz, Brianna Entringer, Xigang Jing, Xingrao Ke, Robert H. Lane, Girija G. Konduri, Pengyuan Liu, Pui Y. Lai, Alison J. Kriegel
Publikováno v:
Physiol Genomics
Background: Fetal growth restriction (FGR) is a major risk factor for bronchopulmonary dysplasia (BPD). Maternal stress and poor diet are linked to FGR. Effect of perinatal stress on lung development remains unknown. Objective: Using a murine model o
Publikováno v:
Physiological Reports
Physiological Reports, Vol 8, Iss 18, Pp n/a-n/a (2020)
Physiological Reports, Vol 8, Iss 18, Pp n/a-n/a (2020)
We investigated the hypothesis that exposure of lungs at the saccular stage of development to hyperoxia leads to persistent growth arrest and dysfunction of 5’AMP‐activated protein kinase (AMPK), a key energy sensor in the cell. We exposed neonat
Autor:
Robert H. Lane, Xigang Jing, Girija G. Konduri, Xingrao Ke, Yi-Wen Huang, Hollis Johnson, Teresa Michalkiewicz
Publikováno v:
Physiological Genomics. 50:828-836
Decreased expression of endothelial nitric oxide synthase (eNOS), a key mediator of perinatal transition, characterizes persistent pulmonary hypertension of the newborn (PPHN) in neonates and a fetal lamb model; the mechanisms are unclear. We investi
Autor:
Adeleye J. Afolayan, Maxwell Alexander, Ru-Jeng Teng, Girija G. Konduri, Teresa Michalkiewicz, Sara Zemanovic, Rebecca L Holme, Ujala Rana, Kirkwood A. Pritchard, Daisy Sahoo
Publikováno v:
Journal of Biological Chemistry. 292:2369-2378
Stress-inducible heat shock protein 70 (hsp70) interacts with superoxide dismutase 2 (SOD2) in the cytosol after synthesis to transfer the enzyme to the mitochondria for subsequent activation. However, the structural basis for this interaction remain
Autor:
Emily Callan, Teresa Michalkiewicz, Ujala Rana, Girija G. Konduri, Ru-Jeng Teng, Brianna Entringer
Publikováno v:
D16. EVERY CELL YOU BREAK: HOW CELLULAR PHENOTYPES CONTRIBUTE TO PAH.
Autor:
Santiago Argote‐Alvarez, Margaret T.T. Wong-Riley, Gary Mouradian, Gabriel Thuku, Matthew R. Hodges, Girija G. Konduri, Teresa Michalkiewicz, Ryan Gorzek
Publikováno v:
The FASEB Journal. 33