Zobrazeno 1 - 10
of 275
pro vyhledávání: '"Teresa, Marafioti"'
Autor:
Robert E. Hynds, Ariana Huebner, David R. Pearce, Mark S. Hill, Ayse U. Akarca, David A. Moore, Sophia Ward, Kate H. C. Gowers, Takahiro Karasaki, Maise Al Bakir, Gareth A. Wilson, Oriol Pich, Carlos Martínez-Ruiz, A. S. Md Mukarram Hossain, Simon P. Pearce, Monica Sivakumar, Assma Ben Aissa, Eva Grönroos, Deepak Chandrasekharan, Krishna K. Kolluri, Rebecca Towns, Kaiwen Wang, Daniel E. Cook, Leticia Bosshard-Carter, Cristina Naceur-Lombardelli, Andrew J. Rowan, Selvaraju Veeriah, Kevin Litchfield, Philip A. J. Crosbie, Caroline Dive, Sergio A. Quezada, Sam M. Janes, Mariam Jamal-Hanjani, Teresa Marafioti, TRACERx consortium, Nicholas McGranahan, Charles Swanton
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Patient-derived xenograft (PDX) models are widely used in cancer research. To investigate the genomic fidelity of non-small cell lung cancer PDX models, we established 48 PDX models from 22 patients enrolled in the TRACERx study. Multi-regio
Externí odkaz:
https://doaj.org/article/15a9cb6171ca46d4a07fbfbe6bf74b76
Autor:
Christos Panayi, Ayse U. Akarca, Alan D. Ramsay, Ananth G. Shankar, Brunangelo Falini, Miguel A. Piris, David Linch, Teresa Marafioti
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundThe clinicopathological spectrum of nodular lymphocyte predominant Hodgkin lymphoma (NLPHL), also known as nodular lymphocyte predominant B-cell lymphoma, partially overlaps with T-cell/histiocyte-rich large B-cell lymphoma (THRLCBL). NLPHL
Externí odkaz:
https://doaj.org/article/a9583936f525471a8aa038037f2ce241
Autor:
Hanyun Zhang, Khalid AbdulJabbar, Tami Grunewald, Ayse U. Akarca, Yeman Hagos, Faranak Sobhani, Catherine S.Y. Lecat, Dominic Patel, Lydia Lee, Manuel Rodriguez-Justo, Kwee Yong, Jonathan A. Ledermann, John Le Quesne, E. Shelley Hwang, Teresa Marafioti, Yinyin Yuan
Publikováno v:
EBioMedicine, Vol 95, Iss , Pp 104769- (2023)
Summary: Background: Efficient biomarker discovery and clinical translation depend on the fast and accurate analytical output from crucial technologies such as multiplex imaging. However, reliable cell classification often requires extensive annotati
Externí odkaz:
https://doaj.org/article/247dba90151c4cdeb67c905958d7c6d9
Integrated phenotyping of the anti-cancer immune response in HIV-associated hepatocellular carcinoma
Autor:
David J. Pinato, Takahiro Kaneko, Antonio D’Alessio, Alejandro Forner, Petros Fessas, Beatriz Minguez, Edoardo G. Giannini, Federica Grillo, Alba Díaz, Francesco A. Mauri, Claudia A.M. Fulgenzi, Alessia Dalla Pria, Robert D. Goldin, Giulia Pieri, Pierluigi Toniutto, Claudio Avellini, Maria Corina Plaz Torres, Ayse U. Akarca, Teresa Marafioti, Sherrie Bhoori, Jose María Miró, Mark Bower, Norbert Bräu, Vincenzo Mazzaferro
Publikováno v:
JHEP Reports, Vol 5, Iss 7, Pp 100741- (2023)
Background & Aims: HIV-seropositivity shortens survival in patients with hepatocellular carcinoma (HCC). Although risk factors for HCC including HCV infection can influence T cell phenotype, it is unknown whether HIV can influence functional characte
Externí odkaz:
https://doaj.org/article/28357346c44e48efaa343ba7b862ee46
Autor:
Andrea Marra, Ayse U Akarca, Giovanni Martino, Alan Ramsay, Stefano Ascani, Vincenzo Maria Perriello, Jenny O’Nions, Andrew J Wilson, Rajeev Gupta, Anna Childerhouse, Ian Proctor, Manuel Rodriguez-Justo, Sabine Pomplun, Maria Paola Martelli, Cristina Lo Celso, Brunangelo Falini, Teresa Marafioti
Publikováno v:
Haematologica, Vol 108, Iss 12 (2023)
Externí odkaz:
https://doaj.org/article/a8dc04b736214618a5eb0413dac11dc1
Autor:
David R. Pearce, Ayse U. Akarca, Roel P. H. De Maeyer, Emily Kostina, Ariana Huebner, Monica Sivakumar, Takahiro Karasaki, Kavina Shah, Sam M. Janes, Nicholas McGranahan, Venkat Reddy, Arne N. Akbar, David A. Moore, Teresa Marafioti, Charles Swanton, Robert E. Hynds
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundPatient-derived xenograft (PDX) models involve the engraftment of tumour tissue in immunocompromised mice and represent an important pre-clinical oncology research method. A limitation of non-small cell lung cancer (NSCLC) PDX model derivat
Externí odkaz:
https://doaj.org/article/cae9afdbf4674ceea00f1d3863b707db
Autor:
Strachan Mackenzie, Manar Shafat, Harriet Roddy, Harpreet Hyare, Lorna Neill, Maria A. V. Marzolini, Michael Gilhooley, Teresa Marafioti, Eleanna Kara, Emilie Sanchez, Jeremy Rees, David S. Lynch, Kirsty Thomson, Kirit M. Ardeshna, Arian Laurence, Karl S. Peggs, Maeve O'Reilly, Claire Roddie
Publikováno v:
eJHaem, Vol 2, Iss 4, Pp 848-853 (2021)
Abstract Progressive multifocal leukoencephalopathy (PML) is an opportunistic brain infection with few treatment options and poor survival when reversal of the underlying immune dysfunction is not achievable. JC polyomavirus reactivation resulting in
Externí odkaz:
https://doaj.org/article/c0d674bf81494667b74ab208dbb6c5eb
Autor:
Matt Lechner, Volker H. Schartinger, Christopher D. Steele, Wen Long Nei, Marc Lucas Ooft, Liesa-Marie Schreiber, Christodoulos P. Pipinikas, Grace Tin-Yun Chung, Yuk Yu Chan, Feng Wu, Ka-Fai To, Chi Man Tsang, Wayne Pearce, Daniele Morelli, Martin Philpott, Liam Masterson, Reshma Nibhani, Graham Wells, Christopher G. Bell, Julia Koller, Susanne Delecluse, Yim Ling Yip, Jacklyn Liu, Cillian T. Forde, Martin D. Forster, Amrita Jay, József Dudás, Annika Krapp, Simon Wan, Christian Uprimny, Susanne Sprung, Johannes Haybaeck, Tim R. Fenton, Kerry Chester, Christina Thirlwell, Gary Royle, Teresa Marafioti, Rajeev Gupta, Sagung Rai Indrasari, Camelia Herdini, Mohd Afiq Mohd Slim, I. Indrawati, Liam Sutton, Renske Fles, Bing Tan, Joe Yeong, Amit Jain, Shuting Han, Haitao Wang, Kelvin S. H. Loke, Wan He, Ruilian Xu, Hongtao Jin, Zhiqiang Cheng, David Howard, Peter H. Hwang, Quynh-Thu Le, Joshua K. Tay, Robert B. West, Sai Wah Tsao, Tim Meyer, Herbert Riechelmann, Udo Oppermann, Henri-Jacques Delecluse, Stefan M. Willems, Melvin L. K. Chua, Pierre Busson, Kwok Wai Lo, Guido Wollmann, Nischalan Pillay, Bart Vanhaesebroeck, Valerie J. Lund
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nasopharyngeal carcinoma (NPC) lacks effective diagnostic and therapeutic strategies, in particular at advanced stages. Here, the authors show that expression of the somatostatin receptor 2 is induced by Epstein-Barr virus in NPC and has a key role i
Externí odkaz:
https://doaj.org/article/ff5d4bfec0f74e349a04c2a36d9baae8
Autor:
Massimo Granai, Lucia Mundo, Ayse U. Akarca, Maria Chiara Siciliano, Hasan Rizvi, Virginia Mancini, Noel Onyango, Joshua Nyagol, Nicholas Othieno Abinya, Ibrahim Maha, Sandra Margielewska, Wenbin Wi, Michele Bibas, Pier Paolo Piccaluga, Leticia Quintanilla-Martinez, Falko Fend, Stefano Lazzi, Lorenzo Leoncini, Teresa Marafioti
Publikováno v:
Infectious Agents and Cancer, Vol 15, Iss 1, Pp 1-8 (2020)
Abstract Background The Tumor Microenviroment (TME) is a complex milieu that is increasingly recognized as a key factor in multiple stages of disease progression and responses to therapy as well as escape from immune surveillance. However, the precis
Externí odkaz:
https://doaj.org/article/4a1bf0e8a3fb480eacc9be50f2a8c94b
Autor:
Vincenzo Mazzaferro, Federica Grillo, Pierluigi Toniutto, Petros Fessas, Francesco A Mauri, Teresa Marafioti, Ayse U Akarca, Alejandro Forner, Robert D Goldin, Alba Díaz, David J. Pinato, Sam M Murray, Takahiro Kaneko, Beatriz Mínguez, Valentina Cacciato, Claudio Avellini, Rosemary J. Boyton, Daniel M. Altmann, Edoardo Casagrande, Edoardo Giannini, Sherrie Bhoori
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/a973066887174810bc7aff81b2ac8b76