Zobrazeno 1 - 10 of 522 pro vyhledávání: '"Teresa, Lozano"'
1
Report
On generic singularities of intersections of ellipsoids: the octahedron
Autor: Bartolo, Enrique Artal, de Medrano, Santiago López, Imìzcoz, María Teresa Lozano
The goal of this work is to study the smoothings of singular coaxial intersections of ellipsoids (where coaxial includes concentric) with generic singularities, with special attention to the 3-dimensional case.
Externí odkaz: http://arxiv.org/abs/2403.20286
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2
Akademický článek
Tethered IL15-IL15Rα augments antitumor activity of CD19 CAR-T cells but displays long-term toxicity in an immunocompetent lymphoma mouse model
Autor: Felipe Prosper, Sandra Hervás-Stubbs, Juan Jose Lasarte, Noelia Casares, Teresa Lozano, Celia Martín-Otal, Aritz Lasarte-Cia, Flor Navarro, Inés Sánchez-Moreno, Marta Gorraiz, Patricia Sarrión, Juan Roberto Rodriguez-Madoz, Jesús San Miguel, Lorea Jordana
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 12, Iss 7 (2024)
Background Adoptive cell therapy using genetically modified T cells to express chimeric antigen receptors (CAR-T) has shown encouraging results, particularly in certain blood cancers. Nevertheless, over 40% of B cell malignancy patients experience a
Externí odkaz: https://doaj.org/article/9476ec368d284e2c9962de6926e355ea
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4
Akademický článek
Intratumoral electroporation of a self-amplifying RNA expressing IL-12 induces antitumor effects in mouse models of cancer
Autor: Noelia Silva-Pilipich, Aritz Lasarte-Cía, Teresa Lozano, Celia Martín-Otal, Juan José Lasarte, Cristian Smerdou
Publikováno v: Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 387-399 (2022)
Alphavirus vectors based on self-amplifying RNA (saRNA) generate high and transient levels of transgene expression and induce innate immune responses, making them an interesting tool for antitumor therapy. These vectors are usually delivered as viral
Externí odkaz: https://doaj.org/article/b1f921f31651413ab141c0f1f87c97c4
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5
Akademický článek
Heart Rate Variability to Automatically Identify Hyperbaric States Considering Respiratory Component
Autor: María Dolores Peláez-Coca, Alberto Hernando, María Teresa Lozano, Juan Bolea, David Izquierdo, Carlos Sánchez
Publikováno v: Sensors, Vol 24, Iss 2, p 447 (2024)
This study’s primary objective was to identify individuals whose physiological responses deviated from the rest of the study population by automatically monitoring atmospheric pressure levels to which they are exposed and using parameters derived f
Externí odkaz: https://doaj.org/article/cc1c3e7b42774f35bc9dbb538b212465
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6
Akademický článek
Overcoming T cell dysfunction in acidic pH to enhance adoptive T cell transfer immunotherapy
Autor: Flor Navarro, Noelia Casares, Celia Martín-Otal, Aritz Lasarte-Cía, Marta Gorraiz, Patricia Sarrión, Diana Llopiz, David Reparaz, Nerea Varo, Juan Roberto Rodriguez-Madoz, Felipe Prosper, Sandra Hervás-Stubbs, Teresa Lozano, Juan José Lasarte
Publikováno v: OncoImmunology, Vol 11, Iss 1 (2022)
The high metabolic activity and insufficient perfusion of tumors leads to the acidification of the tumor microenvironment (TME) that may inhibit the antitumor T cell activity. We found that pharmacological inhibition of the acid loader chloride/bicar
Externí odkaz: https://doaj.org/article/dfa52afd638448c3b908195abc57de8d
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7
Akademický článek
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8
Akademický článek
Enhancing Safety in Hyperbaric Environments through Analysis of Autonomic Nervous System Responses: A Comparison of Dry and Humid Conditions
Autor: Carlos Sánchez, Alberto Hernando, Juan Bolea, David Izquierdo, Germán Rodríguez, Agustín Olea, María Teresa Lozano, María Dolores Peláez-Coca
Publikováno v: Sensors, Vol 23, Iss 11, p 5289 (2023)
Diving can have significant cardiovascular effects on the human body and increase the risk of developing cardiac health issues. This study aimed to investigate the autonomic nervous system (ANS) responses of healthy individuals during simulated dives
Externí odkaz: https://doaj.org/article/cec5ac61bafa442e9c6b9f79bb967bc5
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9
Akademický článek
Targeting the extra domain A of fibronectin for cancer therapy with CAR-T cells
Autor: Felipe Prosper, Sandra Hervás-Stubbs, Juan Jose Lasarte, Noelia Casares, Teresa Lozano, Diego Serrano, Carlos E De Andrea, Alfonso Calvo, Enrique Conde, Celia Martín-Otal, Aritz Lasarte-Cia, Flor Navarro, Inés Sánchez-Moreno, Marta Gorraiz, Patricia Sarrión, José Echeveste, Amaia Vilas, Juan Roberto Rodriguez-Madoz, Jesús San Miguel
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 10, Iss 8 (2022)
Background One of the main difficulties of adoptive cell therapies with chimeric antigen receptor (CAR)-T cells in solid tumors is the identification of specific target antigens. The tumor microenvironment can present suitable antigens for CAR design
Externí odkaz: https://doaj.org/article/c301abd4787842b988871048df0364f6
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10
Akademický článek
Dual activity of PD-L1 targeted Doxorubicin immunoliposomes promoted an enhanced efficacy of the antitumor immune response in melanoma murine model
Autor: María Merino, Teresa Lozano, Noelia Casares, Hugo Lana, Iñaki F. Troconiz, Timo L. M. ten Hagen, Grazyna Kochan, Pedro Berraondo, Sara Zalba, María J. Garrido
Publikováno v: Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Background The immunomodulation of the antitumor response driven by immunocheckpoint inhibitors (ICIs) such as PD-L1 (Programmed Death Ligand-1) monoclonal antibody (α-PD-L1) have shown relevant clinical outcomes in a subset of patients. Th
Externí odkaz: https://doaj.org/article/6d5ca0ef8beb4eb08b6042e8a9bcd005
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