Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Terence S Crofts"'
Publikováno v:
Frontiers in Microbiology, Vol 5 (2014)
Cobamides are a family of enzyme cofactors that include vitamin B12 (cobalamin) and are produced solely by prokaryotes. Structural variability in the lower axial ligand has been observed in cobamides produced by diverse organisms. Of the three classe
Externí odkaz:
https://doaj.org/article/36187d8964f34b478c9b2fa11df8c349
Autor:
Michael W. Mullowney, Natalia I. Maltseva, Michael Endres, Youngchang Kim, Andrzej Joachimiak, Terence S. Crofts
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 2 (2022)
ABSTRACT Phylogenetically diverse bacteria can carry out chloramphenicol reduction, but only a single enzyme has been described that efficiently catalyzes this reaction, the NfsB nitroreductase from Haemophilus influenzae strain KW20. Here, we tested
Externí odkaz:
https://doaj.org/article/10083284a0c145cdad571bcd81c4d296
Publikováno v:
mSystems, Vol 6, Iss 3 (2021)
Medically and industrially important genes can be recovered from microbial communities by high-throughput sequencing, but precise annotation is often limited to characterized genes and their relatives. Cloning a metagenome en masse
Externí odkaz:
https://doaj.org/article/4783ac75e8874e768426eb7ac681cb7f
Functional metagenomic libraries, physical bacterial libraries which allow the high-throughput capture and expression of microbiome genes, have been instrumental in the sequence-naïve and cultivation-independent discovery of novel genes from microbi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c63670905249fed73ac42056c922f789
https://doi.org/10.1101/2021.02.01.429292
https://doi.org/10.1101/2021.02.01.429292
Publikováno v:
Clinical Chemistry. 64:1280-1283
In recent years, immune checkpoint inhibitors (ICIs)5, which block the ability of cancer cells to evade killing by CD8+ T cells, have begun to revolutionize cancer treatment. Since 2011, 6 different ICIs targeting T-cell (PD-1 or CTLA-4) or tumor (PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89131d3aca52cfed278c3a3065198cec
https://doi.org/10.1373/clinchem.2017.286229
https://doi.org/10.1373/clinchem.2017.286229
Autor:
Alaric W. D’Souza, Gautam Dantas, Brad W. Warner, Phillip I. Tarr, J Ning, N Shalon, K Wardenburg, Terence S. Crofts, John I. Robinson, Drew J. Schwartz, Jeffrey P. Henderson
Publikováno v:
Journal of the Pediatric Infectious Diseases Society. 10:S6-S7
Background Premature infants frequently receive antibiotics, which diminishes gut microbial diversity and increases susceptibility to infections by antibiotic resistant pathogens. Neonates with decreased gut microbiota diversity, termed dysbiotic, ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::031754345e7aa2f8309a37faecb28203
https://doi.org/10.1093/jpids/piab031.010
https://doi.org/10.1093/jpids/piab031.010
Publikováno v:
Nature Reviews Microbiology. 15:422-434
Antibiotic resistance is a natural feature of diverse microbial ecosystems. Although recent studies of the antibiotic resistome have highlighted barriers to the horizontal transfer of antibiotic resistance genes between habitats, the rapid global spr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6c732e9fab41ef002e5499680463370
https://doi.org/10.1038/nrmicro.2017.28
https://doi.org/10.1038/nrmicro.2017.28
Autor:
Gautam Dantas, Andrew J. Gasparrini, Molly K. Gibson, Barbara B. Warner, Phillip I. Tarr, Terence S. Crofts
Publikováno v:
Gut Microbes. 7:443-449
The gut microbiota plays important roles in nutrient absorption, immune system development, and pathogen colonization resistance. Perturbations early in life may be detrimental to host health in the short and the long-term. Antibiotics are among the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::835e11580afbeeff6dbbc12bd3101c9b
https://doi.org/10.1080/19490976.2016.1218584
https://doi.org/10.1080/19490976.2016.1218584
Autor:
C. Nicole Rosenzweig, Gautam Dantas, Molly K. Gibson, Morten Otto Alexander Sommer, Kevin J. Forsberg, Lauren A. Johnsky, Bin Wang, Tara A. Gianoulis, Evan W. Skowronski, Aaron Spivak, Terence S. Crofts, Henry S. Gibbons, S. M. Broomall
Publikováno v:
Nature chemical biology
The soil microbiome can produce, resist, or degrade antibiotics and even catabolize them. While resistance genes are widely distributed in the soil, there is a dearth of knowledge concerning antibiotic catabolism. Here we describe a pathway for penic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8122581ada13b53bcee08e24448b21d
https://pubmed.ncbi.nlm.nih.gov/29713061
https://pubmed.ncbi.nlm.nih.gov/29713061
Publikováno v:
Current Opinion in Microbiology. 27:51-56
The microbial communities colonizing the human gut are tremendously diverse and highly personal. The composition and function of the microbiota play important roles in human health and disease, and considerable research has focused on understanding t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::458f2e5b6c71390f8bf623ecc2a42da9
https://doi.org/10.1016/j.mib.2015.07.007
https://doi.org/10.1016/j.mib.2015.07.007