Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Terence R. S. Ozolinš"'
Autor:
Bruce Campbell, Lisa M. Weber, Sandra J. Engle, Terence R. S. Ozolinš, Patricia Bourassa, Robert Aiello, Robert Liefke
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract SAM domain-containing protein 1 (SAMD1) has been implicated in atherosclerosis, as well as in chromatin and transcriptional regulation, suggesting a versatile and complex biological function. However, its role at an organismal level is curre
Externí odkaz:
https://doaj.org/article/927abc85cccb46cd9220c40619921c05
Autor:
Karina T Kasawara, Tiziana Cotechini, Shannyn K Macdonald-Goodfellow, Fernanda G Surita, João L Pinto E Silva, Chandrakant Tayade, Maha Othman, Terence R S Ozolinš, Charles H Graham
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0154405 (2016)
Fetal growth restriction (FGR) and coagulopathies are often associated with aberrant maternal inflammation. Moderate-intensity exercise during pregnancy has been shown to increase utero-placental blood flow and to enhance fetal nutrition as well as f
Externí odkaz:
https://doaj.org/article/3d2bb59e8f664b16aa997e5280b397ff
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1965
Congenital heart defects (CHD) are the most prevalent anomaly both clinically and in laboratory animal species. Historically, it was difficult to assess the longitudinal progression or repair of such anomalies because assessment methodologies were to
Autor:
Terence R S, Ozolinš
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1965
The electrophoretic mobility shift assay (EMSA) is a sensitive relatively straightforward methodology used to detect sequence-specific DNA-protein interactions. It is the fundamental procedure of several variants that allow qualitative and quantitati
Autor:
Terence R S, Ozolinš
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1965
The rabbit is a mainstay of regulatory developmental toxicity testing; however, due to the historic absence of experimental tools for this species, there is a dearth of information about its fundamental embryology and the mechanisms underlying develo
Publikováno v:
Biochemical Pharmacology. 57:1165-1175
Oxidative stress in the conceptus is characterized by an increased oxidized to reduced glutathione (GSSG:GSH) ratio and the induction of fos and jun mRNAs, transcripts for components of the activator protein-1 (AP-1) transcription factor. We investig
Publikováno v:
Teratology. 66(4)
Background Many teratogens induce oxidative stress, altering redox status and redox signaling; this has led to the suggestion that developmental toxicants act by disturbing redox status. The goal of these studies was to determine the consequences of
Post-translational regulation of AP-1 transcription factor DNA-binding activity in the rat conceptus
Publikováno v:
Molecular pharmacology. 56(3)
Activator protein-1 (AP-1) transcription factor DNA binding is induced during transient oxidative stress in the midorganogenesis rat conceptus in culture. l-2-Oxothiazolidine-4-carboxylate (OTC), a cysteine prodrug, prevented oxidative stress and the