Výsledky vyhledávání - "Terence L. Parker"

Arsonoliposomes for the Potential Treatment of Medulloblastoma

Autor: Sophia G. Antimisiaris, Showan Marouf, Marco E. Favretto, Terence L. Parker, Paraskevi Kallinteri, Panagiotis Ioannou

Publikováno v: Pharmaceutical Research. 26:2237-2246

To investigate the arsonoliposome effect on medulloblastoma cells (VC312Rs) related to uptake, endocytotic mechanism and cell viability.VC312R viability in presence of either arsonoliposomes or stealth liposomes was studied using MTT assay for 1-4 da

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb58fbff2653844c466ebc207f1cea02
https://doi.org/10.1007/s11095-009-9940-0

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Retrovirus delivered neurotrophin-3 promotes survival, proliferation and neuronal differentiation of human fetal neural stem cells in vitro

Autor: Pengbo Zhang, Yi-Hua Qian, Xin-li Xiao, Tusheng Song, Xinshun Feng, Terence L. Parker, Haixia Lu, Minjie Li, Xinlin Chen, Yong Liu

Publikováno v: Brain Research Bulletin. 77:158-164

Poor survival and insufficient neuronal differentiation are the main obstacles to neural stem cell (NSC) transplantation therapy. Genetic modification of NSCs with neurotrophins is considered a promising approach to overcome these difficulties. In th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ded30751408f6a645785670a8a12dda9
https://doi.org/10.1016/j.brainresbull.2008.02.037

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Penetration and intracellular uptake of poly(glycerol-adipate) nanoparticles into three-dimensional brain tumour cell culture models

Autor: Martin C. Garnett, David Walker, Weina Meng, Terence L. Parker

Nanoparticle (NP) drug delivery systems may potentially enhance the efficacy of therapeutic agents. It is difficult to characterize many important properties of NPs in vivo and therefore attempts have been made to use realistic in vitro multicellular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98f452a375f185dab79c9682700a3c64
https://europepmc.org/articles/PMC4950476/

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Methoctramine analogues inhibit responses to capsaicin and protons in rat dorsal root ganglion neurons

Autor: Richard H. Clothier, Anna Minarini, Vincenzo Tumiatti, Ian R. Mellor, Terence L. Parker, Carlo Melchiorre, Michela Rosini, Jane Ogilvie, Florentina Pluteanu

Publikováno v: European Journal of Pharmacology. 505:37-50

We have investigated the possibility that vanilloid receptors have a binding site for polyamines and determined the consequences of binding to such a site. Whole-cell and single-channel patch-clamp recordings were used to investigate the effect of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4ad2169d871313efa4bd548b25f99be
https://doi.org/10.1016/j.ejphar.2004.10.005

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Hand pattern indicates prostate cancer risk

Autor: Amanda L. Hall, Jo-Fen Liu, Elizabeth Page, Douglas F. Easton, Terence L. Parker, David P. Dearnaley, Kenneth Muir, Richard Pocock, Rosemary A. Wilkinson, Michelle Guy, John Anderson, Lynne T. O'Brien, Aneela Atta Ur Rahman, Zsofia Kote-Jarai, D. Harriss, Artitaya Lophatananon, Rosalind A. Eeles, Sarah Stewart-Brown, Elinor Sawyer

Publikováno v: British Journal of Cancer

Background: The ratio of digit lengths is fixed in utero, and may be a proxy indicator for prenatal testosterone levels. Methods: We analysed the right-hand pattern and prostate cancer risk in 1524 prostate cancer cases and 3044 population-based cont

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e83f10f17cd0dccc1589007bf068784a
https://doi.org/10.1038/sj.bjc.6605986

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P2-250 Omega 3 polyunsaturated fatty acids (PUFAs) and risk of early onset prostate cancer

Autor: Terence L. Parker, Amanda L. Hall, Douglas F. Easton, J Lobaz, Michelle Guy, R A Wilkinson, David P. Dearnaley, Kenneth Muir, Elizabeth Page, Zsofia Kote-Jarai, S. S. Brown, Rosalind A. Eeles, A Atta Ur Rahman, Richard Pocock, J-F Liu, Fredie Robinson, Artitaya Lophatananon, Emma J. Sawyer

Publikováno v: Journal of Epidemiology & Community Health. 65:A290-A291

Introduction In the UK, approximately 11% of newly registered PrCa cases are under the age of 60 years. The unequal incidence across different countries suggests that modifiable factors, such as dietary intake of omega 3 polyunsaturated fatty acids (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dd24445e66e42637449d5881c90675a1
https://doi.org/10.1136/jech.2011.142976j.83

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Abstract 642: Body fat distribution and prostate cancer risk: A UK case-control study

Autor: Artitaya Lophatananon, David Walker, Rosalind A. Eeles, Amanda L. Hall, Richard Pocock, Zsofia Kote Jarai, Kenneth Muir, Douglas F. Easton, Emma S awyer, Jo-Fen Liu, Fredie Robinson, S. S. Brown, Rosemary A. Wilkinson, Michelle Guy, Terence L. Parker, Aneela Atta Ur Rahman, Elizabeth Page, David P. Dearnaley, Anna M. Grabowska

Publikováno v: Cancer Research. 72:642-642

Background: Prostate cancer is the most common cancer among males in the UK and in 2007 accounted for almost a quarter of all male cancers diagnosed. Previous studies have shown some associations between body size/obesity and prostate cancer risk. Ho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5c82f807dabb7d6e0d7b0a83477ae4cd
https://doi.org/10.1158/1538-7445.am2012-642

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Immobilized Clostridium perfringens neuraminidase. Substrate cleavage and enzyme release during incubation

Autor: Terence L. Parker, Roland Schauer, Anthony P. Corfield, Rüdiger W. Veh

Publikováno v: Hoppe-Seyler's Zeitschrift fur physiologische Chemie. 358(7)

Pure Clostridium perfringens neuraminidase was immobilized on Sepharose 4 B, azido-Sepharose 4 B and controlled pore glass (CPG)- glycophase using different coupling procedures. The immobilized enzyme showed increased stability under various conditio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c4ad9f050cd7ac815d3abd038ac557
https://pubmed.ncbi.nlm.nih.gov/196995

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