Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Terence James Ward"'
Autor:
Norman Lattimer, Neil T. Brammer, Vicki C. Middlefell, Keith F. Rhodes, Valerie L. Saville, James Coleman, Anne P. Taylor, Terence James Ward
Publikováno v:
Drug Development Research. 28:128-140
WAY 100289, endo-N-[8-methyl-8-azabicyclo [3.2.1.] octan-3-yl) aminocarbonyl]-2-cyclopropylmethoxybenzamide, was an antagonist of 5-HT evoked depolarization (5-HT3 receptor-mediated) of the rat isolated cervical vagus nerve (pA2 value 8.9). Schild-pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::675f1d2897bc2815b6904e355fb5504d
https://doi.org/10.1002/ddr.430280203
https://doi.org/10.1002/ddr.430280203
Publikováno v:
Cardiovascular Drug Reviews. 8:117-131
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::456719694f09b099592174cbce12691b
https://doi.org/10.1111/j.1527-3466.1990.tb00434.x
https://doi.org/10.1111/j.1527-3466.1990.tb00434.x
Publikováno v:
ChemInform. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07154ea189d8e17cdfc962204432d05f
https://doi.org/10.1002/chin.199516277
https://doi.org/10.1002/chin.199516277
Autor:
Terence James Ward, Gerald Bradley, Ann Taylor, Keith F. Rhodes, Janet Christine White, James Coleman
Publikováno v:
Journal of medicinal chemistry. 35(9)
A series of benzoylureas derived from bicycle amines were prepared and evaluated for 5-HT3 antagonist activity on the rat isolated vagus nerve. From among these compounds, those analogues which were ortho substituted by an alkoxy group on the benzoyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98e4a56e1fdfacb7ba5c04e6d36b5bd2
https://pubmed.ncbi.nlm.nih.gov/1578478
https://pubmed.ncbi.nlm.nih.gov/1578478
Autor:
C. Ennis, G. Bradley, J. L. Archibald, A. Opalko, Terence James Ward, J. C. White, N. B. Shepperson
Publikováno v:
ChemInform. 21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2666e0b2e8db4863b26d29390f669823
https://doi.org/10.1002/chin.199024169
https://doi.org/10.1002/chin.199024169
Autor:
Terence James Ward, Nicholas B. Shepperson, John L. Archibald, Gerald Bradley, Janet Christine White, Christine Ennis, Albert Opalko
Publikováno v:
Journal of medicinal chemistry. 33(2)
An approach to the design of potential combined antithrombotic-antihypertensive agents is described. A series of 1,4-dihydropyridines bearing a 1H-imidazol-1-yl or pyrid-3-yl substituted side chain in the 2-position were synthesized and tested for an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0834f368583426a598568babe475e13
https://pubmed.ncbi.nlm.nih.gov/2299629
https://pubmed.ncbi.nlm.nih.gov/2299629
Autor:
Shobna Sharma, Norman Lattimer, Keith F. Rhodes, John F. Waterfall, Terence James Ward, John F. White
Publikováno v:
Journal of Medicinal Chemistry. 31:1421-1426
A series of 2-sulfonamido-1,3,4,6,7,11b alpha-hexahydro-2H-benzo[a]quinolizines were synthesized and examined for alpha 2- and alpha 1-adrenoceptor antagonist activity on the rat vas deferens and anococcygeus muscle, respectively. A number of compoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c441aa0bc53c2b49f05c7253905355c8
https://doi.org/10.1021/jm00402a029
https://doi.org/10.1021/jm00402a029
Publikováno v:
Journal of medicinal chemistry. 28(11)
A series of N-(aminoiminomethyl)-1H-pyrrole-1-acetamides, related to guanfacine, were prepared and tested for antidiarrheal activity in castor oil dosed rats. trans-N-(Aminoiminomethyl)-2,5-dihydro-2,5-dimethyl-1H-pyrrole-1-acetami de (2), in which t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b242c6756cc64f83ae4a5c0adb846ec7
https://pubmed.ncbi.nlm.nih.gov/3906127
https://pubmed.ncbi.nlm.nih.gov/3906127
Publikováno v:
Chemischer Informationsdienst. 17
A series of N-(aminoiminomethyl)-1H-pyrrole-1-acetamides, related to guanfacine, were prepared and tested for antidiarrheal activity in castor oil dosed rats. trans-N-(Aminoiminomethyl)-2,5-dihydro-2,5-dimethyl-1H-pyrrole-1-acetami de (2), in which t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f94684c42374bc5d42f0e90c6ca8dc9e
https://doi.org/10.1002/chin.198609156
https://doi.org/10.1002/chin.198609156
Publikováno v:
Journal of medicinal chemistry. 32(1)
A series of disulfonamidobenzo[a]quinolizines were synthesized and evaluated for their alpha 2- and alpha 1-adrenoceptor antagonist activity on the rat vas deferens and anococcygeus muscle, respectively. N-((2 beta,11b alpha)-1,3,4,6,7,11b-Hexahydro-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42596d56e2cc16ee25fd9769896bf2a9
https://pubmed.ncbi.nlm.nih.gov/2562854
https://pubmed.ncbi.nlm.nih.gov/2562854