Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Terence J. Scallen"'
Publikováno v:
Journal of Lipid Research, Vol 10, Iss 1, Pp 121-127 (1969)
Although indirect evidence has implicated Δ5,7,24-cholestatrien-3β-ol a possible intermediate in cholesterol biosynthesis, this sterol has not previously been isolated from tissues. Administration of two inhibitors of cholesterol biosynthesis to pi
Externí odkaz:
https://doaj.org/article/a10892e8140b484fbb74f742f9e5c239
Autor:
Terence J. Scallen, William Krueger
Publikováno v:
Journal of Lipid Research, Vol 9, Iss 1, Pp 120-128 (1968)
The infrared (IR) and nuclear magnetic resonance (NMR) spectra of eight Δ24-steroids and nine C-24 saturated steroids were examined. NMR spectra allow unambiguous assignment of the biologically important Δ24-bond; introduction of a Δ24-bond causes
Externí odkaz:
https://doaj.org/article/5ad5e3eb710e4d6ca33c194110198e96
Autor:
Terence J. Scallen, T.R. Vedamanda, John A. Brinkman, Lawerence B. Perez, Fell Jay Bradford, Robert E. Damon
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:2491-2494
Squalene synthase catalyzes the committed step of cholesterol biosynthesis. We report here the synthesis and in vivo activity of a series of squalene synthase inhibitors that contain isosteric replacements for the farnesyl chain of the known inhibito
Publikováno v:
Tissue and Cell. 27:483-490
In the present investigation, we have studied peroxisomes and sterol carrier protein-2 (SCP2) in control and luteinizing hormone stimulated rat luteal cells. Superovulated immature rats in mid-luteal phase (8 days after ovulation) were divided into t
Publikováno v:
Journal of Lipid Research, Vol 35, Iss 12, Pp 2241-2253 (1994)
The role of oxysterols as regulatory molecules in the suppression of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase activity was investigated in the intact rat in response to an acute dietary cholesterol challenge. When rats were fed highl
Publikováno v:
Journal of Biological Chemistry. 266:9885-9892
Sterol carrier protein-2 (SCP-2) is an intracellular protein of Mr 13,096. In vitro studies have shown that it is involved in the transport and metabolism of cholesterol. This protein is believed to participate in these activities by forming a stoich
Publikováno v:
Agricultural and Biological Chemistry. 54:2649-2653
Publikováno v:
Tissuecell. 30(1)
We investigated the chronic effects of luteinizing hormone (LH) treatment on adult rat Leydig cell structure and function. Two groups of sexually mature male Sprague-Dawley rats were used; controls and rats implanted subdermally with LH-filled Alzet
Publikováno v:
Intracellular Cholesterol Trafficking ISBN: 9781461373261
Intact, dispersed adrenal fasiculata cells were fused with liposomal entrapped anti-sterol carrier protein-2 IgG, washed and subsequently exposed to adrenocorticotropic hormone (ACTH). The steroidogenic response (measured as corticosterone production
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::114615227009ce9654cfdd46242df7a5
https://doi.org/10.1007/978-1-4615-5113-3_13
https://doi.org/10.1007/978-1-4615-5113-3_13
Publikováno v:
Biochemical Society transactions. 20(4)
818 Introduction Lipid transport between intracellular organelles is thought to involve carrier proteins. Several different lipid transfer proteins have been isolated which are involved in the transport of phosphatidylcholine, phosphatidylinositol, p