Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Terence Hwa"'
Autor:
Jacob M. Robertson, Erin A. Garza, Astrid K. M. Stubbusch, Christopher L. Dupont, Terence Hwa, Noelle A. Held
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT The physiology and ecology of particle-associated marine bacteria are of growing interest, but our knowledge of their aggregation behavior and mechanisms controlling their association with particles remains limited. We have found that a part
Externí odkaz:
https://doaj.org/article/f235580710e44e92b1b6c6bd6a14e0b6
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Quantifying the contribution of individual molecular components to complex cellular processes is a grand challenge in systems biology. Here we establish a general theoretical framework (Functional Decomposition of Metabolism, FDM) to quantif
Externí odkaz:
https://doaj.org/article/b4dc6275337448f4af01f13cbc5a41b6
Autor:
Kapil Amarnath, Avaneesh V. Narla, Sammy Pontrelli, Jiajia Dong, Jack Reddan, Brian R. Taylor, Tolga Caglar, Julia Schwartzman, Uwe Sauer, Otto X. Cordero, Terence Hwa
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Metabolic cross-feeding plays vital roles in promoting ecological diversity. While some microbes depend on exchanges of essential nutrients for growth, the forces driving the extensive cross-feeding needed to support the coexistence of free-
Externí odkaz:
https://doaj.org/article/9dbaa8d64d9f4f34a6612b1d1d63eb8c
Autor:
Arion Iffland-Stettner, Hiroyuki Okano, Matti Gralka, Ghita Guessous, Kapil Amarnath, Otto X. Cordero, Terence Hwa, Sebastian Bonhoeffer
Publikováno v:
mSystems, Vol 8, Iss 2 (2023)
ABSTRACT While Vibrio splendidus is best known as an opportunistic pathogen in oysters, Vibrio splendidus strain 1A01 was first identified as an early colonizer of synthetic chitin particles incubated in seawater. To gain a better understanding of it
Externí odkaz:
https://doaj.org/article/91c1a5bf3d5e4c2bbb4514440a08019a
Autor:
Trang T. H. Nguyen, Emily J. Zakem, Ali Ebrahimi, Julia Schwartzman, Tolga Caglar, Kapil Amarnath, Uria Alcolombri, François J. Peaudecerf, Terence Hwa, Roman Stocker, Otto X. Cordero, Naomi M. Levine
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Micro-scale microbial community dynamics can substantially alter the fate of sinking particulates in the ocean thus playing a key role in setting the vertical flux of particulate carbon in the ocean.
Externí odkaz:
https://doaj.org/article/44a4ee9b15e84b4bb16ea918e8bd75dd
Autor:
Matteo Mori, Zhongge Zhang, Amir Banaei‐Esfahani, Jean‐Benoît Lalanne, Hiroyuki Okano, Ben C Collins, Alexander Schmidt, Olga T Schubert, Deok‐Sun Lee, Gene‐Wei Li, Ruedi Aebersold, Terence Hwa, Christina Ludwig
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 5, Pp 1-23 (2021)
Abstract Accurate measurements of cellular protein concentrations are invaluable to quantitative studies of gene expression and physiology in living cells. Here, we developed a versatile mass spectrometric workflow based on data‐independent acquisi
Externí odkaz:
https://doaj.org/article/6aa5a86f417842f5b356db6414fccb62
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 12, Pp n/a-n/a (2021)
Abstract To respond to fluctuating conditions, microbes typically need to synthesize novel proteins. As this synthesis relies on sufficient biosynthetic precursors, microbes must devise effective response strategies to manage depleting precursors. To
Externí odkaz:
https://doaj.org/article/309003d5d30c42b09e3b712abf202acf
Publikováno v:
PLoS Biology, Vol 19, Iss 10 (2021)
Much recent progress has been made to understand the impact of proteome allocation on bacterial growth; much less is known about the relationship between the abundances of the enzymes and their substrates, which jointly determine metabolic fluxes. He
Externí odkaz:
https://doaj.org/article/0e3306f0e85b4afeb0e9973df3446271
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 4, Pp n/a-n/a (2021)
Abstract Microorganisms adjust metabolic activity to cope with diverse environments. While many studies have provided insights into how individual pathways are regulated, the mechanisms that give rise to coordinated metabolic responses are poorly und
Externí odkaz:
https://doaj.org/article/9d87f7ba792142a3a79dabdc70a48189
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Fast-growing bacteria produce many proteins in excess of what seems optimal for exponential growth. Here, the authors present a mathematical model and experimental evidence supporting that this overexpression serves as a strategic reserve to quickly
Externí odkaz:
https://doaj.org/article/3544e922e215469b80235c1a59ad032b