Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Terence E. Nicholas"'
Autor:
Ian R. Doyle, Heather A. Barr, Kate G. Davidson, Terence E. Nicholas, Andrew D. Bersten, Kay D. Dowling
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 279:L1091-L1102
Although acute lung injury (ALI) is associated with inflammation and surfactant dysfunction, the precise sequence of these changes remains poorly described. We used oleic acid to study the pathogenesis of ALI in spontaneously breathing anesthetized r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63079b61e8bf4bd94afbd2f1be92d132
https://doi.org/10.1152/ajplung.2000.279.6.l1091
https://doi.org/10.1152/ajplung.2000.279.6.l1091
Publikováno v:
Journal of Experimental Biology. 202:2543-2550
The Australian lungfish Neoceratodus forsteri is the most primitive member of the lungfish family, with a surfactant lipid composition similar to the actinopterygiian fishes, which evolved 400 million years ago. We have analysed the proteins associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7aff7a0addbd0554d1d713fcc3fb5f6
https://doi.org/10.1242/jeb.202.18.2543
https://doi.org/10.1242/jeb.202.18.2543
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 26:185-197
1. The alveolocapillary membrane faces an extraordinary task in partitioning the plasma and lung hypophase proteins, with a surface area approximately 50-fold that of the body and only 0.1–0.2 μm thick. 2. Lung permeability is compromised under a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b69f843ace898c1ade05fbfa2ae8267
https://doi.org/10.1046/j.1440-1681.1999.03015.x
https://doi.org/10.1046/j.1440-1681.1999.03015.x
Autor:
John H. T. Power, Terence E. Nicholas
Publikováno v:
Experimental Lung Research. 25:379-392
We have purified and partially sequenced a 26-kDa protein isolated from rat lung lavage. Two-dimensional electrophoresis and Western blotting using an antibody we have raised to this protein indicated that CC26 has 3 isoforms with pIs between 4.9 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ebb1a025011d809ef22598b66407782
https://doi.org/10.1080/019021499270141
https://doi.org/10.1080/019021499270141
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 158:1528-1535
Surfactant proteins A and B (SP-A and SP-B) enter the circulation in a manner that acutely reflects changes in pulmonary function in patients with acute respiratory failure (ARF). There is a small but significant gradient in SP-A and SP-B from arteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb1539eff3b22d3618997ef568d4eb3
https://doi.org/10.1164/ajrccm.158.5.9712097
https://doi.org/10.1164/ajrccm.158.5.9712097
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 25:955-963
1. Although abnormalities in pulmonary surfactant were initially implicated in the pathogenesis of the acute respiratory distress syndrome (ARDS) 30 years ago, most subsequent research has focused on mediators of the parenchymal acute lung injury (AL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::496e771f6ccca46607a66f2ddc82ed15
https://doi.org/10.1111/j.1440-1681.1998.tb02352.x
https://doi.org/10.1111/j.1440-1681.1998.tb02352.x
Autor:
Yasmin S. Edwards, John H. T. Power, Terence E. Nicholas, Leanne M. Sutherland, Andrew W. Murray
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 275:L670-L678
The aim of this study was to analyze the effects of osmotic shock and secretagogues such as ATP and 12- O-tetradecanoylphorbol 13-acetate (TPA) on various intracellular signaling pathways in primary cultures of alveolar type II cells and examine thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::201cd03c89170f519ba3a17ba70cc590
https://doi.org/10.1152/ajplung.1998.275.4.l670
https://doi.org/10.1152/ajplung.1998.275.4.l670
Autor:
John J. Finlay-Jones, Jeff Bowden, Sharon Morton, Julie Rowe, Prue H. Hart, Terence E. Nicholas
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 17:218-226
Tumor necrosis factor alpha (TNF-alpha), a major product of alveolar macrophages (AM), has been implicated in many pulmonary diseases. Histamine, a mediator important in pulmonary inflammation, has been demonstrated to regulate the production of TNF-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0b5667840aa45eae7f05cfe740d53a5
https://doi.org/10.1165/ajrcmb.17.2.2722
https://doi.org/10.1165/ajrcmb.17.2.2722
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 272:L106-L114
Treatment of rats with 10 mg.kg body wt-1 day-1 4-aminopyrazolo[3,4-d]pyrimidine (APP) for 2 days markedly reduced serum cholesterol and phospholipids. This was associated with large decreases in the principal component of alveolar surfactant, the di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb2b73bd5e28d4daf86476205e9cf226
https://doi.org/10.1152/ajplung.1997.272.1.l106
https://doi.org/10.1152/ajplung.1997.272.1.l106
Autor:
Terence E. Nicholas
Publikováno v:
Respirology. 1:247-257
The gas-liquid interface within the alveolus is completely lined with a complex mixture of lipids and unique proteins termed pulmonary surfactant, which both reduces surface tension and permits it to vary directly with the radius of curvature. In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff9a98a7d16b30d20556c27144e4385
https://doi.org/10.1111/j.1440-1843.1996.tb00040.x
https://doi.org/10.1111/j.1440-1843.1996.tb00040.x